4TNE
| Crystal Structure of Human Transthyretin Thr119Tyr Mutant | Descriptor: | GLYCEROL, Transthyretin | Authors: | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | Deposit date: | 2014-06-03 | Release date: | 2015-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Uncovering the Mechanism of Aggregation of Human Transthyretin. J.Biol.Chem., 290, 2015
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4TLS
| Crystal Structure of Human Transthyretin Glu92Pro Mutant | Descriptor: | GLYCEROL, PHOSPHATE ION, SODIUM ION, ... | Authors: | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | Deposit date: | 2014-05-30 | Release date: | 2015-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Uncovering the Mechanism of Aggregation of Human Transthyretin. J.Biol.Chem., 290, 2015
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4TLT
| Crystal structure of human transthyretin | Descriptor: | MAGNESIUM ION, Transthyretin | Authors: | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | Deposit date: | 2014-05-30 | Release date: | 2015-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Uncovering the Mechanism of Aggregation of Human Transthyretin. J.Biol.Chem., 290, 2015
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4TLK
| Crystal Structure of Human Transthyretin Ser85Pro/Glu92Pro Mutant | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, SODIUM ION, ... | Authors: | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | Deposit date: | 2014-05-30 | Release date: | 2015-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Uncovering the Mechanism of Aggregation of Human Transthyretin. J.Biol.Chem., 290, 2015
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4TM9
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4UNV
| Covalent dimer of lambda variable domains | Descriptor: | IG LAMBDA CHAIN V-II REGION MGC, SULFATE ION | Authors: | Brumshtein, B, Esswein, S, Landau, M, Ryan, C, Whitelegge, J, Sawaya, M, Eisenberg, D.S. | Deposit date: | 2014-05-30 | Release date: | 2014-08-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains. J.Biol.Chem., 289, 2014
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1ZYT
| Crystal structure of spin labeled T4 Lysozyme (A82R1) | Descriptor: | 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ... | Authors: | Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L. | Deposit date: | 2005-06-10 | Release date: | 2006-08-15 | Last modified: | 2023-10-25 | Method: | EPR (1.7 Å), X-RAY DIFFRACTION | Cite: | Structural origin of weakly ordered nitroxide motion in spin-labeled proteins Protein Sci., 18, 2009
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5WMJ
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5IM5
| Crystal structure of designed two-component self-assembling icosahedral cage I53-40 | Descriptor: | Designed Keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase, Designed Riboflavin synthase | Authors: | Liu, Y.A, Cascio, D, Sawaya, M.R, Bale, J.B, Collazo, M.J, Thomas, C, Sheffler, W, King, N.P, Baker, D, Yeates, T.O. | Deposit date: | 2016-03-05 | Release date: | 2016-07-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.699 Å) | Cite: | Accurate design of megadalton-scale two-component icosahedral protein complexes. Science, 353, 2016
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5IM6
| Crystal structure of designed two-component self-assembling icosahedral cage I32-28 | Descriptor: | Designed self-assembling icosahedral cage I32-28 dimeric subunit, Designed self-assembling icosahedral cage I32-28 trimeric subunit | Authors: | Liu, Y.A, Cascio, D, Sawaya, M.R, Bale, J.B, Collazo, M.J, Thomas, C, Sheffler, W, King, N.P, Baker, D, Yeates, T.O. | Deposit date: | 2016-03-05 | Release date: | 2016-07-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (5.588 Å) | Cite: | Accurate design of megadalton-scale two-component icosahedral protein complexes. Science, 353, 2016
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5IM4
| Crystal structure of designed two-component self-assembling icosahedral cage I52-32 | Descriptor: | 6,7-dimethyl-8-ribityllumazine synthase, Phosphotransferase system, mannose/fructose-specific component IIA | Authors: | Liu, Y.A, Cascio, D, Sawaya, M.R, Bale, J.B, Collazo, M.J, Thomas, C, Sheffler, W, King, N.P, Baker, D, Yeates, T.O. | Deposit date: | 2016-03-05 | Release date: | 2016-07-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Accurate design of megadalton-scale two-component icosahedral protein complexes. Science, 353, 2016
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4I0X
| Crystal structure of the Mycobacterum abscessus EsxEF (Mab_3112-Mab_3113) complex | Descriptor: | BETA-MERCAPTOETHANOL, ESAT-6-like protein MAB_3112, ESAT-6-like protein MAB_3113, ... | Authors: | Arbing, M.A, Chan, S, Lu, J, Kuo, E, Harris, L, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2012-11-19 | Release date: | 2013-01-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.956 Å) | Cite: | Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions. Plos One, 8, 2013
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2F44
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4L4W
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1JOL
| THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX BETWEEN FOLINIC ACID (LEUCOVORIN) AND E. COLI DIHYDROFOLATE REDUCTASE | Descriptor: | CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ... | Authors: | Lee, H, Reyes, V.M, Kraut, J. | Deposit date: | 1996-02-25 | Release date: | 1996-11-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal structures of Escherichia coli dihydrofolate reductase complexed with 5-formyltetrahydrofolate (folinic acid) in two space groups: evidence for enolization of pteridine O4. Biochemistry, 35, 1996
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1JOM
| THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX BETWEEN FOLINIC ACID (LEUCOVORIN) AND E. COLI DIHYDROFOLATE REDUCTASE | Descriptor: | CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ... | Authors: | Reyes, V.M, Lee, H, Kraut, J. | Deposit date: | 1996-02-25 | Release date: | 1996-11-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of Escherichia coli dihydrofolate reductase complexed with 5-formyltetrahydrofolate (folinic acid) in two space groups: evidence for enolization of pteridine O4. Biochemistry, 35, 1996
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2F3N
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1S3Q
| Crystal structures of a novel open pore ferritin from the hyperthermophilic Archaeon Archaeoglobus fulgidus | Descriptor: | ZINC ION, ferritin | Authors: | Johnson, E, Cascio, D, Sawaya, M, Schroeder, I. | Deposit date: | 2004-01-13 | Release date: | 2005-04-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of a tetrahedral open pore ferritin from the hyperthermophilic archaeon Archaeoglobus fulgidus. Structure, 13, 2005
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5DFN
| Structure of Tetrahymena Telomerase P45 C-terminal domain | Descriptor: | Telomerase associated protein p45 | Authors: | Chan, H, Cascio, D, Sawaya, M.R, Feigon, J. | Deposit date: | 2015-08-27 | Release date: | 2015-10-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.382 Å) | Cite: | Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions. Science, 350, 2015
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5DFM
| Structure of Tetrahymena telomerase p19 fused to MBP | Descriptor: | GLYCEROL, Maltose-binding periplasmic protein,Telomerase-associated protein 19, SULFATE ION, ... | Authors: | Chan, H, Cascio, D, Sawaya, M.R, Feigon, J. | Deposit date: | 2015-08-27 | Release date: | 2015-10-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions. Science, 350, 2015
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1JB8
| The Crystal Structure of an RNA/DNA Hybrid Reveals Novel Intermolecular Intercalation | Descriptor: | 5'-D(*CP*TP*TP*TP*TP*CP*TP*TP*TP*G)-3', 5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3' | Authors: | Han, G.W, Kopka, M.L, Langs, D, Dickerson, R.E. | Deposit date: | 2001-06-02 | Release date: | 2003-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Crystal structure of an RNADNA hybrid reveals intermolecular
intercalation: Dimer formation by base-pair swapping Proc.Natl.Acad.Sci.USA, 100, 2003
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1DYJ
| ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS | Descriptor: | 5,10-DIDEAZATETRAHYDROFOLIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Reyes, V.M, Kraut, J. | Deposit date: | 1994-10-26 | Release date: | 1995-06-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications. Biochemistry, 34, 1995
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1DYH
| ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS | Descriptor: | 5-DEAZAFOLIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Reyes, V.M, Kraut, J. | Deposit date: | 1994-10-26 | Release date: | 1995-06-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications. Biochemistry, 34, 1995
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1DYI
| ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS | Descriptor: | CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ... | Authors: | Reyes, V.M, Kraut, J. | Deposit date: | 1994-10-26 | Release date: | 1995-06-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications. Biochemistry, 34, 1995
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5SXL
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