2ZGR
| |
2ZGS
| |
6M53
| Crystal structure of 2, 3-dihydroxybenzoic acid decarboxylase from Fusarium oxysporum | Descriptor: | 2,3-dihydroxybenzoate decarboxylase, GLYCEROL, ZINC ION | Authors: | Song, M.K, Feng, J.H, Liu, W.D, Wu, Q.Q, Zhu, D.M. | Deposit date: | 2020-03-09 | Release date: | 2020-07-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | 2,3-Dihydroxybenzoic Acid Decarboxylase from Fusarium oxysporum: Crystal Structures and Substrate Recognition Mechanism. Chembiochem, 21, 2020
|
|
7YJ1
| Cryo-EM structure of SPT-ORMDL3 (ORMDL3-deltaN2) complex | Descriptor: | ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | Authors: | Xie, T, Liu, P, Gong, X. | Deposit date: | 2022-07-19 | Release date: | 2023-07-05 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis. Nat Commun, 14, 2023
|
|
7YJ2
| Cryo-EM structure of SPT-ORMDL3 (ORMDL3-N13A) complex | Descriptor: | ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | Authors: | Xie, T, Liu, P, Gong, X. | Deposit date: | 2022-07-19 | Release date: | 2023-07-05 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis. Nat Commun, 14, 2023
|
|
7YIU
| Cryo-EM structure of the C6-ceramide-bound SPT-ORMDL3 complex | Descriptor: | HEXADECANE, N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)HEXANAMIDE, ORM1-like protein 3, ... | Authors: | Xie, T, Liu, P, Gong, X. | Deposit date: | 2022-07-18 | Release date: | 2023-07-05 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis. Nat Commun, 14, 2023
|
|
7YIY
| Cryo-EM structure of SPT-ORMDL3 complex | Descriptor: | N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Xie, T, Liu, P, Gong, X. | Deposit date: | 2022-07-18 | Release date: | 2023-07-05 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis. Nat Commun, 14, 2023
|
|
5Z9T
| a new PL6 alginate lyase complex with trisaccharide | Descriptor: | GLYCEROL, MALONATE ION, SODIUM ION, ... | Authors: | Liu, W.Z, Lyu, Q.Q, Zhang, K.K, Li, Z.J. | Deposit date: | 2018-02-05 | Release date: | 2019-03-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into a novel Ca2+-independent PL-6 alginate lyase from Vibrio OU02 identify the possible subsites responsible for product distribution. Biochim Biophys Acta Gen Subj, 1863, 2019
|
|
6A40
| complex structure of Alginate lyase AlyF-OU02 with G4 | Descriptor: | alginate lyase AlyF-OU02, alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid | Authors: | Liu, W.Z, Lyu, Q.Q, Zhang, K.K. | Deposit date: | 2018-06-18 | Release date: | 2019-05-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into a novel Ca2+-independent PL-6 alginate lyase from Vibrio OU02 identify the possible subsites responsible for product distribution. Biochim Biophys Acta Gen Subj, 1863, 2019
|
|
6A92
| Crystal structure of a cyclase Filc1 from Fischerella sp. | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, TETRAETHYLENE GLYCOL, ... | Authors: | Hu, X.Y, Liu, W.D, Chen, C.C, Guo, R.T. | Deposit date: | 2018-07-11 | Release date: | 2018-12-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement Angew. Chem. Int. Ed. Engl., 57, 2018
|
|
6ITG
| a new alginate lyase (PL6) from Vibrio splendidus OU02 | Descriptor: | Alginate lyase, GLYCEROL, MALONATE ION | Authors: | Liu, W.Z, Lyu, Q.Q. | Deposit date: | 2018-11-23 | Release date: | 2019-05-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Structural insights into a novel Ca2+-independent PL-6 alginate lyase from Vibrio OU02 identify the possible subsites responsible for product distribution. Biochim Biophys Acta Gen Subj, 1863, 2019
|
|
5ZXA
| Crystal structure of fibronectin-binding protein Apa mutant from Mycobacterium tuberculosis | Descriptor: | Alanine and proline-rich secreted protein Apa, GLYCEROL, MERCURY (II) ION | Authors: | Gao, J, Liu, W.D, Chen, C.C, Guo, R.T. | Deposit date: | 2018-05-18 | Release date: | 2019-05-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Functional and structural investigations of fibronectin-binding protein Apa from Mycobacterium tuberculosis. Biochim Biophys Acta Gen Subj, 1863, 2019
|
|
5ZX9
| Crystal structure of apo form fibronectin-binding protein Apa from Mycobacterium tuberculosis | Descriptor: | Alanine and proline-rich secreted protein Apa, GLYCEROL | Authors: | Gao, J, Liu, W.D, Chen, C.C, Guo, R.T. | Deposit date: | 2018-05-18 | Release date: | 2019-05-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Functional and structural investigations of fibronectin-binding protein Apa from Mycobacterium tuberculosis. Biochim Biophys Acta Gen Subj, 1863, 2019
|
|
6A9F
| Crystal structure of a cyclase from Fischerella sp. TAU in complex with 4-(1H-Indol-3-yl)butan-2-one | Descriptor: | 4-(1~{H}-indol-3-yl)butan-2-one, CALCIUM ION, GLYCEROL, ... | Authors: | Hu, X.Y, Liu, W.D, Chen, C.C, Guo, R.T. | Deposit date: | 2018-07-13 | Release date: | 2018-12-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement Angew. Chem. Int. Ed. Engl., 57, 2018
|
|
6A99
| Crystal structure of a Stig cyclases Fisc from Fischerella sp. TAU in complex with (3Z)-3-(1-methyl-2-pyrrolidinylidene)-3H-indole | Descriptor: | (3~{Z})-3-(1-methylpyrrolidin-2-ylidene)indole, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Hu, X.Y, Liu, W.D, Chen, C.C, Guo, R.T. | Deposit date: | 2018-07-12 | Release date: | 2018-12-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement Angew. Chem. Int. Ed. Engl., 57, 2018
|
|
6ADU
| Crystal structure of an enzyme in complex with ligand C | Descriptor: | (3~{Z})-3-(1-methylpyrrolidin-2-ylidene)indole, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | Authors: | Tan, X.K, Liu, W.D, Chen, C.C, Guo, R.T. | Deposit date: | 2018-08-02 | Release date: | 2019-08-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement. Angew.Chem.Int.Ed.Engl., 57, 2018
|
|
8W88
| Cryo-EM structure of the SEP363856-bound TAAR1-Gs complex | Descriptor: | 1-[(7~{S})-5,7-dihydro-4~{H}-thieno[2,3-c]pyran-7-yl]-~{N}-methyl-methanamine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Liu, H, Zheng, Y, Wang, Y, Wang, Y, He, X, Xu, P, Huang, S, Yuan, Q, Zhang, X, Wang, S, Xu, H.E, Xu, F. | Deposit date: | 2023-09-01 | Release date: | 2023-11-22 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Recognition of methamphetamine and other amines by trace amine receptor TAAR1. Nature, 624, 2023
|
|
8W8B
| Cryo-EM structure of SEP-363856 bounded serotonin 1A (5-HT1A) receptor-Gi protein complex | Descriptor: | 1-[(7~{S})-5,7-dihydro-4~{H}-thieno[2,3-c]pyran-7-yl]-~{N}-methyl-methanamine, Antibody fragment scFv16, CHOLESTEROL, ... | Authors: | Liu, H, Zheng, Y, Wang, Y, Wang, Y, He, X, Xu, P, Huang, S, Yuan, Q, Zhang, X, Wang, S, Xu, H.E, Xu, F. | Deposit date: | 2023-09-01 | Release date: | 2023-11-22 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Recognition of methamphetamine and other amines by trace amine receptor TAAR1. Nature, 624, 2023
|
|
8W87
| Cryo-EM structure of the METH-TAAR1 complex | Descriptor: | (2S)-N-methyl-1-phenylpropan-2-amine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, H, Zheng, Y, Wang, Y, Wang, Y, He, X, Xu, P, Huang, S, Yuan, Q, Zhang, X, Wang, S, Xu, H.E, Xu, F. | Deposit date: | 2023-09-01 | Release date: | 2023-11-22 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Recognition of methamphetamine and other amines by trace amine receptor TAAR1. Nature, 624, 2023
|
|
8W8A
| Cryo-EM structure of the RO5256390-TAAR1 complex | Descriptor: | (4S)-4-[(2S)-2-phenylbutyl]-1,3-oxazolidin-2-imine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, H, Zheng, Y, Wang, Y, Wang, Y, He, X, Xu, P, Huang, S, Yuan, Q, Zhang, X, Wang, S, Xu, H.E, Xu, F. | Deposit date: | 2023-09-01 | Release date: | 2023-11-22 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Recognition of methamphetamine and other amines by trace amine receptor TAAR1. Nature, 624, 2023
|
|
8W89
| Cryo-EM structure of the PEA-bound TAAR1-Gs complex | Descriptor: | 2-PHENYLETHYLAMINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, H, Zheng, Y, Wang, Y, Wang, Y, He, X, Xu, P, Huang, S, Yuan, Q, Zhang, X, Wang, S, Xu, H.E, Xu, F. | Deposit date: | 2023-09-01 | Release date: | 2023-11-22 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Recognition of methamphetamine and other amines by trace amine receptor TAAR1. Nature, 624, 2023
|
|
6KA2
| Crystal structure of a Thebaine synthase from Papaver somniferum in complex with TBN | Descriptor: | (4R,7aR,12bS)-7,9-dimethoxy-3-methyl-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline, Thebaine synthase 2 | Authors: | Xue, J, Yu, X.J, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | Deposit date: | 2019-06-20 | Release date: | 2020-06-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural insights into thebaine synthase 2 catalysis. Biochem.Biophys.Res.Commun., 529, 2020
|
|
6KA3
| Crystal structure of a Thebaine synthase from Papaver somniferum | Descriptor: | PALMITIC ACID, SULFATE ION, Thebaine synthase 2 | Authors: | Xue, J, Yu, X.J, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | Deposit date: | 2019-06-20 | Release date: | 2020-06-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.951 Å) | Cite: | Structural insights into thebaine synthase 2 catalysis. Biochem.Biophys.Res.Commun., 529, 2020
|
|
6IHI
| Crystal structure of RasADH 3B3/I91V from Ralstonia.sp in complex with NADPH and A6O | Descriptor: | (2R,3S)-2-ethyl-2-[(2E)-2-(6-methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)ethyl]-3-oxidanyl-cyclopentan-1-one, Alclohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Zhang, H.L, Chen, X, Liu, W.D, Wu, Q.Q, Zhu, D.M. | Deposit date: | 2018-09-30 | Release date: | 2019-10-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Efficient reductive desymmetrization of bulky 1,3-cyclodiketones enabled by structure-guided directed evolution of a carbonyl reductase. Nat Catal, 2, 2019
|
|
6IHH
| Crystal structure of RasADH F12 from Ralstonia.sp in complex with NADPH and A6O | Descriptor: | (2R,3S)-2-ethyl-2-[(2E)-2-(6-methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)ethyl]-3-oxidanyl-cyclopentan-1-one, Alclohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Zhang, H.L, Chen, X, Liu, W.D, Wu, Q.Q, Zhu, D.M. | Deposit date: | 2018-09-30 | Release date: | 2019-10-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Efficient reductive desymmetrization of bulky 1,3-cyclodiketones enabled by structure-guided directed evolution of a carbonyl reductase. Nat Catal, 2, 2019
|
|