8W88
Cryo-EM structure of the SEP363856-bound TAAR1-Gs complex
Summary for 8W88
Entry DOI | 10.2210/pdb8w88/pdb |
EMDB information | 37348 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | taar1, sep-363856, gpcr, antipsychotics, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 147278.00 |
Authors | |
Primary citation | Liu, H.,Zheng, Y.,Wang, Y.,Wang, Y.,He, X.,Xu, P.,Huang, S.,Yuan, Q.,Zhang, X.,Wang, L.,Jiang, K.,Chen, H.,Li, Z.,Liu, W.,Wang, S.,Xu, H.E.,Xu, F. Recognition of methamphetamine and other amines by trace amine receptor TAAR1. Nature, 624:663-671, 2023 Cited by PubMed: 37935377DOI: 10.1038/s41586-023-06775-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.6 Å) |
Structure validation
Download full validation report