8JLF
 
 | | Cryo-EM structure of SV2A in complex with BoNT/A2 Hc | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin, ... | | Authors: | Yamagata, A. | | Deposit date: | 2023-06-02 | | Release date: | 2024-05-01 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
Nat Commun, 15, 2024
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8JLE
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8JS8
 | | Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and levetiracetam | | Descriptor: | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Yamagata, A. | | Deposit date: | 2023-06-19 | | Release date: | 2024-05-01 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (2.88 Å) | | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
Nat Commun, 15, 2024
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8JLG
 | | Cryo-EM structure of SV2A in complex with BoNT/A2 Hc | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin, ... | | Authors: | Yamagata, A. | | Deposit date: | 2023-06-02 | | Release date: | 2024-05-01 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (2.87 Å) | | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
Nat Commun, 15, 2024
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8JLC
 | | Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and levetiracetam | | Descriptor: | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Yamagata, A. | | Deposit date: | 2023-06-02 | | Release date: | 2024-05-01 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (2.88 Å) | | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
Nat Commun, 15, 2024
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8JLH
 | | Cryo-EM structure of SV2A dimer in complex with BoNT/A2 Hc and levetiracetam | | Descriptor: | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Yamagata, A. | | Deposit date: | 2023-06-02 | | Release date: | 2024-05-01 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
Nat Commun, 15, 2024
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8JLI
 | | Cryo-EM structure of SV2A dimer in complex levetiracetam | | Descriptor: | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, Synaptic vesicle glycoprotein 2A | | Authors: | Yamagata, A. | | Deposit date: | 2023-06-02 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
Nat Commun, 15, 2024
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6LCE
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6LCF
 | | Crystal Structure of beta-L-arabinobiose binding protein - native | | Descriptor: | ABC transporter substrate binding component, beta-L-arabinofuranose-(1-2)-beta-L-arabinofuranose | | Authors: | Miyake, M, Arakawa, T, Fushinobu, S. | | Deposit date: | 2019-11-18 | | Release date: | 2020-04-22 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Structural analysis of beta-L-arabinobiose-binding protein in the metabolic pathway of hydroxyproline-rich glycoproteins in Bifidobacterium longum.
Febs J., 287, 2020
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8K77
 | | Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and brivaracetam | | Descriptor: | (2S)-2-[(4R)-2-oxidanylidene-4-propyl-pyrrolidin-1-yl]butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Yamagata, A. | | Deposit date: | 2023-07-26 | | Release date: | 2024-05-01 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.11 Å) | | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
Nat Commun, 15, 2024
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3VJO
 | | Crystal structure of the wild-type EGFR kinase domain in complex with AMPPNP. | | Descriptor: | Epidermal growth factor receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Semba, K, Yamamoto, T, Yokoyama, S. | | Deposit date: | 2011-10-27 | | Release date: | 2012-03-07 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.64 Å) | | Cite: | Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor.
Oncogene, 32, 2013
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3VJN
 | | Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in complex with AMPPNP. | | Descriptor: | Epidermal growth factor receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Semba, K, Yamamoto, T, Yokoyama, S. | | Deposit date: | 2011-10-27 | | Release date: | 2012-03-07 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor.
Oncogene, 32, 2013
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2RPD
 | | Mhr1p-bound ssDNA | | Descriptor: | DNA (5'-D(*DTP*DAP*DCP*DG)-3') | | Authors: | Masuda, T, Ito, Y, Shibata, T, Mikawa, T. | | Deposit date: | 2008-05-15 | | Release date: | 2009-05-26 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | A non-canonical DNA structure enables homologous recombination in various genetic systems
J.Biol.Chem., 284, 2009
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5B52
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2RPF
 | | RecO-bound ssDNA | | Descriptor: | DNA (5'-D(*DTP*DAP*DCP*DG)-3') | | Authors: | Masuda, T, Ito, Y, Shibata, T, Mikawa, T. | | Deposit date: | 2008-05-15 | | Release date: | 2009-05-26 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | A non-canonical DNA structure enables homologous recombination in various genetic systems
J.Biol.Chem., 284, 2009
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2RPH
 | | RecT-bound ssDNA | | Descriptor: | DNA (5'-D(*DTP*DAP*DCP*DG)-3') | | Authors: | Masuda, T, Ito, Y, Shibata, T, Mikawa, T. | | Deposit date: | 2008-05-15 | | Release date: | 2009-05-26 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | A non-canonical DNA structure enables homologous recombination in various genetic systems
J.Biol.Chem., 284, 2009
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2RPE
 | | hsRad51-bound ssDNA | | Descriptor: | DNA (5'-D(*DTP*DAP*DCP*DG)-3') | | Authors: | Masuda, T, Ito, Y, Shibata, T, Mikawa, T. | | Deposit date: | 2008-05-15 | | Release date: | 2009-05-26 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | A non-canonical DNA structure enables homologous recombination in various genetic systems
J.Biol.Chem., 284, 2009
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5AYQ
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3UG1
 | | Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in the apo form | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor | | Authors: | Parker, L.J, Handa, N, Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. | | Deposit date: | 2011-11-02 | | Release date: | 2012-03-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor
Oncogene, 32, 2013
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3UG2
 | | Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in complex with gefitinib | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor, Gefitinib | | Authors: | Parker, L.J, Handa, N, Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. | | Deposit date: | 2011-11-02 | | Release date: | 2012-03-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor
Oncogene, 32, 2013
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1WJ0
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3WEX
 | | Crystal structure of HLA-DP5 in complex with Cry j 1-derived peptide (residues 214-222) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II antigen | | Authors: | Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. | | Deposit date: | 2013-07-16 | | Release date: | 2014-07-23 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for the specific recognition of the major antigenic peptide from the Japanese cedar pollen allergen Cry j 1 by HLA-DP5
J. Mol. Biol., 426, 2014
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1WIJ
 | | Solution Structure of the DNA-Binding Domain of Ethylene-Insensitive3-Like3 | | Descriptor: | ETHYLENE-INSENSITIVE3-like 3 protein | | Authors: | Yamasaki, K, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-28 | | Release date: | 2004-11-28 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the major DNA-binding domain of Arabidopsis thaliana ethylene-insensitive3-like3.
J.Mol.Biol., 348, 2005
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1IXD
 | | Solution structure of the CAP-GLY domain from human cylindromatosis tomour-suppressor CYLD | | Descriptor: | Cylindromatosis tumour-suppressor CYLD | | Authors: | Saito, K, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2002-06-19 | | Release date: | 2002-12-19 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | The CAP-Gly domain of CYLD associates with the proline-rich sequence in NEMO/IKKgamma
STRUCTURE, 12, 2004
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1IVZ
 | | Solution structure of the SEA domain from murine hypothetical protein homologous to human mucin 16 | | Descriptor: | hypothetical protein 1110008I14RIK | | Authors: | Maeda, T, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2002-04-02 | | Release date: | 2002-10-02 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the SEA domain from the murine homologue of ovarian cancer antigen CA125 (MUC16)
J.Biol.Chem., 279, 2004
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