1RH6
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![BU of 1rh6 by Molmil](/molmil-images/mine/1rh6) | Bacteriophage Lambda Excisionase (Xis)-DNA Complex | Descriptor: | 5'-D(*CP*TP*AP*TP*GP*TP*AP*GP*TP*CP*TP*GP*TP*TP*G)-3', 5'-D(P*CP*AP*AP*CP*AP*GP*AP*CP*TP*AP*CP*AP*TP*AP*G)-3', Excisionase | Authors: | Sam, M.D, Cascio, D, Johnson, R.C, Clubb, R.T. | Deposit date: | 2003-11-13 | Release date: | 2004-06-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of the excisionase-DNA complex from bacteriophage lambda. J.Mol.Biol., 338, 2004
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7PQ5
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![BU of 7pq5 by Molmil](/molmil-images/mine/7pq5) | Photorhabdus laumondii T6SS-associated Rhs protein carrying the Tre23 toxin domain | Descriptor: | Tre23 | Authors: | Jurenas, D, Talachia Rosa, L, Rey, M, Chamot-Rooke, J, Fronzes, R, Cascales, E. | Deposit date: | 2021-09-16 | Release date: | 2021-12-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Mounting, structure and autocleavage of a type VI secretion-associated Rhs polymorphic toxin. Nat Commun, 12, 2021
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5L82
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1RTK
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![BU of 1rtk by Molmil](/molmil-images/mine/1rtk) | Crystal Structure Analysis of the Bb segment of Factor B complexed with 4-guanidinobenzoic acid | Descriptor: | 4-carbamimidamidobenzoic acid, Complement factor B Bb fragment, IODIDE ION, ... | Authors: | Ponnuraj, K, Xu, Y, Macon, K, Moore, D, Volanakis, J.E, Narayana, S.V. | Deposit date: | 2003-12-10 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase. Mol.Cell, 14, 2004
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1RDF
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![BU of 1rdf by Molmil](/molmil-images/mine/1rdf) | G50P mutant of phosphonoacetaldehyde hydrolase in complex with substrate analogue vinyl sulfonate | Descriptor: | ETHANESULFONIC ACID, MAGNESIUM ION, phosphonoacetaldehyde hydrolase | Authors: | Lahiri, S.D, Zhang, G, Dunaway-Mariano, D, Allen, K.N. | Deposit date: | 2003-11-05 | Release date: | 2004-08-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Analysis of the substrate specificity loop of the HAD superfamily cap domain Biochemistry, 43, 2004
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1RUC
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![BU of 1ruc by Molmil](/molmil-images/mine/1ruc) | RHINOVIRUS 14 MUTANT N1105S COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52035 | Descriptor: | 5-(5-(4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, RHINOVIRUS 14 | Authors: | Hadfield, A, Oliveira, M.A, Kim, K.H, Minor, I, Kremer, M.J, Heinz, B.A, Shepard, D, Pevear, D.C, Rueckert, R.R, Rossmann, M.G. | Deposit date: | 1995-06-09 | Release date: | 1995-11-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural studies on human rhinovirus 14 drug-resistant compensation mutants. J.Mol.Biol., 253, 1995
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1R3Z
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![BU of 1r3z by Molmil](/molmil-images/mine/1r3z) | Crystal structures of d(Gm5CGm5CGCGC) and d(GCGCGm5CGm5C): Effects of methylation on alternating DNA octamers | Descriptor: | 5'-D(*GP*(5CM)P*GP*(5CM)P*GP*CP*GP*C)-3' | Authors: | Shi, K, Pan, B, Tippin, D, Sundaralingam, M. | Deposit date: | 2003-10-03 | Release date: | 2003-12-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structures of d(Gm5)CGm5CGCGC) and d(GCGCGm5CGm5C): effects of methylation on alternating DNA octamers. Acta Crystallogr.,Sect.D, 60, 2004
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1RIU
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![BU of 1riu by Molmil](/molmil-images/mine/1riu) | Anti-Cocaine Antibody M82G2 Complexed With Norbenzoylecgonine | Descriptor: | 3-(BENZOYLOXY)-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID, Fab M82G2, Heavy Chain, ... | Authors: | Pozharski, E, Hewagama, A, Shanafelt, A, Petsko, G, Ringe, D. | Deposit date: | 2003-11-18 | Release date: | 2003-12-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Carving a Binding Site: Structural Study of an Anti-Cocaine Antibody in Complex with Three Cocaine Analogs To be Published
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1R71
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![BU of 1r71 by Molmil](/molmil-images/mine/1r71) | Crystal Structure of the DNA binding domain of KorB in complex with the operator DNA | Descriptor: | 5'-D(*AP*(BRU)P*TP*TP*TP*AP*GP*CP*GP*GP*CP*TP*AP*AP*AP*AP*G)-3', 5'-D(*CP*(BRU)P*TP*TP*TP*AP*GP*CP*CP*GP*CP*TP*AP*AP*AP*AP*(BRU))-3', Transcriptional repressor protein korB | Authors: | Khare, D, Ziegelin, G, Lanka, E, Heinemann, U. | Deposit date: | 2003-10-17 | Release date: | 2004-06-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Sequence-specific DNA binding determined by contacts outside the helix-turn-helix motif of the ParB homolog KorB. Nat.Struct.Mol.Biol., 11, 2004
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1R84
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![BU of 1r84 by Molmil](/molmil-images/mine/1r84) | NMR structure of the 13-cis-15-syn retinal in dark_adapted bacteriorhodopsin | Descriptor: | Bacteriorhodopsin, RETINAL | Authors: | Patzelt, H, Simon, B, Ter Laak, A, Kessler, B, Kuhne, R, Schmieder, P, Oesterhaelt, D, Oschkinat, H. | Deposit date: | 2003-10-23 | Release date: | 2003-11-11 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | The structures of the active center in dark-adapted bacteriorhodopsin by solution-state NMR spectroscopy Proc.Natl.Acad.Sci.USA, 99, 2002
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1RQN
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![BU of 1rqn by Molmil](/molmil-images/mine/1rqn) | Phosphonoacetaldehyde hydrolase complexed with magnesium | Descriptor: | MAGNESIUM ION, Phosphonoacetaldehyde Hydrolase | Authors: | Morais, M.C, Zhang, G, Zhang, W, Olsen, D.B, Dunaway-Mariano, D, Allen, K.N. | Deposit date: | 2003-12-05 | Release date: | 2004-04-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | X-ray crystallographic and site-directed mutagenesis
analysis of the mechanism of Schiff-base formation in
phosphonoacetaldehyde hydrolase catalysis J.Biol.Chem., 279, 2004
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1RII
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![BU of 1rii by Molmil](/molmil-images/mine/1rii) | Crystal structure of phosphoglycerate mutase from M. Tuberculosis | Descriptor: | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, GLYCEROL | Authors: | Mueller, P, Sawaya, M.R, Chan, S, Wu, Y, Pashkova, I, Perry, J, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-11-17 | Release date: | 2004-10-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The 1.70 angstroms X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase. Acta Crystallogr.,Sect.D, 61, 2005
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1RTF
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5LO0
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![BU of 5lo0 by Molmil](/molmil-images/mine/5lo0) | HSP90 WITH indazole derivative | Descriptor: | Heat shock protein HSP 90-alpha, [2-azanyl-6-[4,5-bis(fluoranyl)-2-(4-methylpiperazin-1-yl)sulfonyl-phenyl]quinazolin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone | Authors: | Graedler, U, Amaral, M, Schuetz, D. | Deposit date: | 2016-08-08 | Release date: | 2017-11-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Ligand Desolvation Steers On-Rate and Impacts Drug Residence Time of Heat Shock Protein 90 (Hsp90) Inhibitors. J. Med. Chem., 61, 2018
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5LPY
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1R29
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![BU of 1r29 by Molmil](/molmil-images/mine/1r29) | Crystal Structure of the B-Cell Lymphoma 6 (BCL6) BTB Domain to 1.3 Angstrom | Descriptor: | B-cell lymphoma 6 protein | Authors: | Ahmad, K.F, Melnick, A, Lax, S.A, Bouchard, D, Liu, J, Kiang, C.L, Mayer, S, Licht, J.D, Prive, G.G. | Deposit date: | 2003-09-26 | Release date: | 2003-12-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain. Mol.Cell, 12, 2003
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1R5M
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5LNZ
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![BU of 5lnz by Molmil](/molmil-images/mine/5lnz) | HSP90 WITH indazole derivative | Descriptor: | Heat shock protein HSP 90-alpha, ~{N}3-butyl-~{N}3,~{N}5-dimethyl-~{N}5-(4-morpholin-4-ylphenyl)-6-oxidanyl-2~{H}-indazole-3,5-dicarboxamide | Authors: | Graedler, U, Amaral, M, Schuetz, D. | Deposit date: | 2016-08-08 | Release date: | 2017-11-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Ligand Desolvation Steers On-Rate and Impacts Drug Residence Time of Heat Shock Protein 90 (Hsp90) Inhibitors. J. Med. Chem., 61, 2018
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1RUG
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![BU of 1rug by Molmil](/molmil-images/mine/1rug) | RHINOVIRUS 14 MUTANT N1219S COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52035 | Descriptor: | 5-(5-(4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, RHINOVIRUS 14 | Authors: | Hadfield, A, Oliveira, M.A, Kim, K.H, Minor, I, Kremer, M.J, Heinz, B.A, Shepard, D, Pevear, D.C, Rueckert, R.R, Rossmann, M.G. | Deposit date: | 1995-06-09 | Release date: | 1995-11-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural studies on human rhinovirus 14 drug-resistant compensation mutants. J.Mol.Biol., 253, 1995
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1R41
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![BU of 1r41 by Molmil](/molmil-images/mine/1r41) | Crystal structures of d(Gm5CGm5CGCGC) and d(GCGCGm5CGm5C): Effects of methylation on alternating DNA octamers | Descriptor: | 5'-D(*GP*CP*GP*CP*GP*(5CM)P*GP*(5CM))-3' | Authors: | Shi, K, Pan, B, Tippin, D, Sundaralingam, M. | Deposit date: | 2003-10-03 | Release date: | 2003-12-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of d(Gm5)CGm5CGCGC) and d(GCGCGm5CGm5C): effects of methylation on alternating DNA octamers. Acta Crystallogr.,Sect.D, 60, 2004
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1R6Q
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![BU of 1r6q by Molmil](/molmil-images/mine/1r6q) | ClpNS with fragments | Descriptor: | ATP-dependent Clp protease ATP-binding subunit clpA, ATP-dependent Clp protease adaptor protein clpS, BIS-(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE YTTRIUM, ... | Authors: | Xia, D, Maurizi, M.R, Guo, F, Singh, S.K, Esser, L. | Deposit date: | 2003-10-16 | Release date: | 2005-02-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone. J.Struct.Biol., 146, 2004
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4K12
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![BU of 4k12 by Molmil](/molmil-images/mine/4k12) | Structural Basis for Host Specificity of Factor H Binding by Streptococcus pneumoniae | Descriptor: | Choline binding protein A, Complement factor H | Authors: | Liu, A, Achila, D, Banerjee, R, Martinez-Hackert, E, Li, Y, Yan, H. | Deposit date: | 2013-04-04 | Release date: | 2014-04-09 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.079 Å) | Cite: | Structural determinants of host specificity of complement Factor H recruitment by Streptococcus pneumoniae. Biochem.J., 465, 2015
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8BJT
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![BU of 8bjt by Molmil](/molmil-images/mine/8bjt) | Structure of human PLK1 in complex with 2-Allyl-1-[6-(1-hydroxy-1-methyl-ethyl)-pyridin-2-yl]-6-[4-(4-methyl-piperazin-1-yl)-phenylamino]-1,2-dihydro-pyrazolo[3,4-d]pyrimidin-3-one | Descriptor: | 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, ACETATE ION, Serine/threonine-protein kinase PLK1, ... | Authors: | Musil, D, Liu-Bujalski, L. | Deposit date: | 2022-11-06 | Release date: | 2023-04-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.188 Å) | Cite: | Selective Wee1 Inhibitors Led to Antitumor Activity In Vitro and Correlated with Myelosuppression. Acs Med.Chem.Lett., 14, 2023
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8BSE
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![BU of 8bse by Molmil](/molmil-images/mine/8bse) | CRYSTAL STRUCTURE OF SARS-COV-2 RECEPTOR BINDING DOMAIN (RBD) in complex with 1D1 Fab | Descriptor: | 1D1 FAB HEAVY CHAIN, 1D1 FAB LIGHT CHAIN, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | Authors: | Welin, M, Kimbung, Y.R, Focht, D, Pisitkun, T. | Deposit date: | 2022-11-25 | Release date: | 2023-05-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Efficacy of the combination of monoclonal antibodies against the SARS-CoV-2 Beta and Delta variants. Plos One, 18, 2023
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8BSC
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![BU of 8bsc by Molmil](/molmil-images/mine/8bsc) | |