6M6Q
| Crystal structure of Caenorhabditis elegans Dicer-related helicase 3 (DRH-3) N-terminal domain | Descriptor: | Dicer Related Helicase | Authors: | Li, K, Zheng, J, Wirawan, M, Xiong, Z, Fedorova, O, Griffin, P, Plyle, A, Luo, D. | Deposit date: | 2020-03-16 | Release date: | 2021-03-17 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Insights into the structure and RNA-binding specificity of Caenorhabditis elegans Dicer-related helicase 3 (DRH-3). Nucleic Acids Res., 49, 2021
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6M6S
| Crystal structure of Caenorhabditis elegans Dicer-related helicase 3 (DRH-3) C-terminal domain with 5'-ppp 12-mer dsRNA | Descriptor: | Dicer Related Helicase, RNA (5'-R(*(GTP)P*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ZINC ION | Authors: | Li, K, Zheng, J, Wirawan, M, Xiong, Z, Fedorova, O, Griffin, P, Plyle, A, Luo, D. | Deposit date: | 2020-03-16 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Insights into the structure and RNA-binding specificity of Caenorhabditis elegans Dicer-related helicase 3 (DRH-3). Nucleic Acids Res., 49, 2021
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7WIX
| Cryo-EM structure of Mycobacterium tuberculosis irtAB in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mycobactin import ATP-binding/permease protein IrtA, ... | Authors: | Zhang, B, Sun, S, Yang, H, Rao, Z. | Deposit date: | 2022-01-05 | Release date: | 2023-01-25 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB. Protein Cell, 14, 2023
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7WIV
| Cryo-EM structure of Mycobacterium tuberculosis irtAB in complex with an AMP-PNP | Descriptor: | Mycobactin import ATP-binding/permease protein IrtA, Mycobactin import ATP-binding/permease protein IrtB, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Zhang, B, Sun, S, Yang, H, Rao, Z. | Deposit date: | 2022-01-05 | Release date: | 2023-01-25 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB. Protein Cell, 14, 2023
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7WIU
| Cryo-EM structure of Mycobacterium tuberculosis irtAB in inward-facing state | Descriptor: | Mycobactin import ATP-binding/permease protein IrtA, Mycobactin import ATP-binding/permease protein IrtB | Authors: | Zhang, B, Sun, S, Yang, H, Rao, Z. | Deposit date: | 2022-01-05 | Release date: | 2023-01-25 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB. Protein Cell, 14, 2023
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7WIW
| Cryo-EM structure of Mycobacterium tuberculosis irtAB complexed with ATP in an occluded conformation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mycobactin import ATP-binding/permease protein IrtA, ... | Authors: | Zhang, B, Sun, S, Yang, H, Rao, Z. | Deposit date: | 2022-01-05 | Release date: | 2023-01-25 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB. Protein Cell, 14, 2023
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7WNX
| Cryo-EM structure of Mycobacterium smegmatis MmpL3 complexed with ST004 in lipid nanodiscs | Descriptor: | N-[2-(2-adamantylamino)ethyl]-1-[2,4-bis(fluoranyl)phenyl]-5-(4-chlorophenyl)-4-methyl-pyrazole-3-carboxamide, Trehalose monomycolate exporter MmpL3 | Authors: | Zhang, B, Hu, T, Yang, X, Liu, F, Rao, Z. | Deposit date: | 2022-01-20 | Release date: | 2022-08-03 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Structure-based design of anti-mycobacterial drug leads that target the mycolic acid transporter MmpL3. Structure, 30, 2022
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7UAD
| Crystal structure of human PTPN2 with inhibitor ABBV-CLS-484 | Descriptor: | 5-{(7R)-1-fluoro-3-hydroxy-7-[(3-methylbutyl)amino]-5,6,7,8-tetrahydronaphthalen-2-yl}-1lambda~6~,2,5-thiadiazolidine-1,1,3-trione, Tyrosine-protein phosphatase non-receptor type 2 | Authors: | Longenecker, K.L, Qiu, W, Sun, Q, Frost, J.M. | Deposit date: | 2022-03-12 | Release date: | 2023-07-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.044 Å) | Cite: | The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity. Nature, 622, 2023
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