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7SMR
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BU of 7smr by Molmil
Cryo-EM structure of Torpedo acetylcholine receptor in complex with carbachol, desensitized state
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E.
Deposit date:2021-10-26
Release date:2022-03-09
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
8VQY
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BU of 8vqy by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus methaqualone
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Chojnacka, W, Teng, J, Kim, J.J, Jensen, A.A, Hibbs, R.E.
Deposit date:2024-01-19
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus methaqualone
To be published
8VRN
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BU of 8vrn by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus PPTQ
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(4-methylphenyl)-2-phenylquinazolin-4(3H)-one, ...
Authors:Chojnacka, W, Teng, J, Kim, J.J, Jensen, A.A, Hibbs, R.E.
Deposit date:2024-01-22
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus methaqualone
To be published
8DD3
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BU of 8dd3 by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus DMCM
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Zhu, S, Hibbs, R.E.
Deposit date:2022-06-17
Release date:2022-08-17
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and dynamic mechanisms of GABA A receptor modulators with opposing activities.
Nat Commun, 13, 2022
8DD2
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BU of 8dd2 by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus Zolpidem
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Zhu, S, Hibbs, R.E.
Deposit date:2022-06-17
Release date:2022-08-17
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and dynamic mechanisms of GABA A receptor modulators with opposing activities.
Nat Commun, 13, 2022
6CNK
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BU of 6cnk by Molmil
Structure of the 3alpha2beta stiochiometry of the human Alpha4Beta2 nicotinic receptor
Descriptor: (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
Authors:Walsh Jr, R.M, Roh, S.H, Gharpure, A, Morales-Perez, C.L, Hibbs, R.E.
Deposit date:2018-03-08
Release date:2018-05-02
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural principles of distinct assemblies of the human alpha 4 beta 2 nicotinic receptor.
Nature, 557, 2018
8SID
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BU of 8sid by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus dehydroepiandrosterone sulfate
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Legesse, D.H, Hibbs, R.E.
Deposit date:2023-04-14
Release date:2023-08-30
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:Structural insights into opposing actions of neurosteroids on GABA A receptors.
Nat Commun, 14, 2023
8SI9
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BU of 8si9 by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus allopregnanolone
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Legesse, D.H, Hibbs, R.E.
Deposit date:2023-04-14
Release date:2023-08-30
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Structural insights into opposing actions of neurosteroids on GABA A receptors.
Nat Commun, 14, 2023
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