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6O4I
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BU of 6o4i by Molmil
Structure of ALDH7A1 mutant E399D complexed with alpha-aminoadipate
Descriptor: 1,2-ETHANEDIOL, 2-AMINOHEXANEDIOIC ACID, Alpha-aminoadipic semialdehyde dehydrogenase
Authors:Tanner, J.J, Korasick, D.A, Laciak, A.R.
Deposit date:2019-02-28
Release date:2019-11-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural analysis of pathogenic mutations targeting Glu427 of ALDH7A1, the hot spot residue of pyridoxine-dependent epilepsy.
J. Inherit. Metab. Dis., 43, 2020
3ITG
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BU of 3itg by Molmil
Structure the proline utilization A proline dehydrogenase domain (PutA86-630) inactivated with N-propargylglycine
Descriptor: Bifunctional protein putA, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE
Authors:Tanner, J.J.
Deposit date:2009-08-28
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structure of the proline utilization a proline dehydrogenase domain inactivated by N-propargylglycine provides insight into conformational changes induced by substrate binding and flavin reduction.
Biochemistry, 49, 2010
3HAZ
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BU of 3haz by Molmil
Crystal structure of bifunctional proline utilization A (PutA) protein
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Tanner, J.J.
Deposit date:2009-05-03
Release date:2010-02-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the bifunctional proline utilization A flavoenzyme from Bradyrhizobium japonicum
Proc.Natl.Acad.Sci.USA, 107, 2010
7SQN
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BU of 7sqn by Molmil
Structure of the E. coli PutA proline dehydrogenase domain (residues 86-630) complexed with (2S)-oxetane-2-carboxylic acid
Descriptor: (2S)-oxetane-2-carboxylic acid, Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Bogner, A.N.
Deposit date:2021-11-05
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure-affinity relationships of reversible proline analog inhibitors targeting proline dehydrogenase.
Org.Biomol.Chem., 20, 2022
7US3
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BU of 7us3 by Molmil
Structure of Putrescine N-hydroxylase Involved Complexed with NADP+
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putrescine N-hydroxylase, ...
Authors:Tanner, J.J, Bogner, A.N.
Deposit date:2022-04-22
Release date:2022-11-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Kinetic and Structural Characterization of a Flavin-Dependent Putrescine N -Hydroxylase from Acinetobacter baumannii.
Biochemistry, 61, 2022
1TJ1
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BU of 1tj1 by Molmil
Crystal structure of E. coli PutA proline dehydrogenase domain (residues 86-669) complexed with L-lactate
Descriptor: (2S)-2-HYDROXYPROPANOIC ACID, Bifunctional putA protein, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Tanner, J.J, Zhang, M, White, T.A, Schuermann, J.P, Baban, B.A, Becker, D.F.
Deposit date:2004-06-03
Release date:2004-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the Escherichia coli PutA proline dehydrogenase domain in complex with competitive inhibitors
Biochemistry, 43, 2004
1TJ2
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BU of 1tj2 by Molmil
Crystal structure of E. coli PutA proline dehydrogenase domain (residues 86-669) complexed with acetate
Descriptor: ACETATE ION, Bifunctional putA protein, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Tanner, J.J, Zhang, M, White, T.A, Schuermann, J.P, Baban, B.A, Becker, D.F.
Deposit date:2004-06-03
Release date:2004-10-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structures of the Escherichia coli PutA proline dehydrogenase domain in complex with competitive inhibitors
Biochemistry, 43, 2004
4O8A
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BU of 4o8a by Molmil
First structure of a proline utilization A proline dehydrogenase domain
Descriptor: (2S)-2-HYDROXYPROPANOIC ACID, Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J.
Deposit date:2013-12-26
Release date:2014-01-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the proline dehydrogenase domain of the multifunctional PutA flavoprotein.
Nat.Struct.Biol., 10, 2003
7JVK
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BU of 7jvk by Molmil
Structure of the M101A variant of the SidA ornithine hydroxylase with the FAD in the "out" conformation
Descriptor: ACETATE ION, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-08-21
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants of Flavin Dynamics in a Class B Monooxygenase.
Biochemistry, 59, 2020
7JVL
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BU of 7jvl by Molmil
Structure of the M101A variant of the SidA ornithine hydroxylase complexed with NADP and the FAD in the "out" conformation
Descriptor: ACETATE ION, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-08-21
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Determinants of Flavin Dynamics in a Class B Monooxygenase.
Biochemistry, 59, 2020
7LRN
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BU of 7lrn by Molmil
Structure of the Siderophore Interacting Protein from Acinetbacter baumannii
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADPH-dependent ferric siderophore reductase
Authors:Tanner, J.J, Korasick, D.A.
Deposit date:2021-02-16
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural and Biochemical Characterization of the Flavin-Dependent Siderophore-Interacting Protein from Acinetobacter baumannii .
Acs Omega, 6, 2021
5HHF
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BU of 5hhf by Molmil
Crystal structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant H63A with covalent FAD-Galactopyranose and bound UDP
Descriptor: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, MESO-ERYTHRITOL, SULFATE ION, ...
Authors:Tanner, J.J.
Deposit date:2016-01-10
Release date:2016-02-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:In Crystallo Capture of a Covalent Intermediate in the UDP-Galactopyranose Mutase Reaction.
Biochemistry, 55, 2016
7MYA
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BU of 7mya by Molmil
Structure of proline utilization A with the FAD covalently-modified by 1,3-dithiolane
Descriptor: Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2021-05-20
Release date:2021-09-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles.
Acs Chem.Biol., 16, 2021
7MYC
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BU of 7myc by Molmil
Structure of proline utilization A with the FAD covalently modified by tetrahydrothiophene
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2021-05-20
Release date:2021-09-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles.
Acs Chem.Biol., 16, 2021
4ZVW
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BU of 4zvw by Molmil
Structure of apo human ALDH7A1 in space group C2
Descriptor: Alpha-aminoadipic semialdehyde dehydrogenase
Authors:Tanner, J.J.
Deposit date:2015-05-18
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1.
Biochemistry, 54, 2015
6D97
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BU of 6d97 by Molmil
Structure of aldehyde dehydrogenase 12 (ALDH12) from Zea mays
Descriptor: Aldehyde dehydrogenase 12, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Tanner, J.J, Korasick, D.A, Kopecny, D.
Deposit date:2018-04-27
Release date:2019-01-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Biochemical Characterization of Aldehyde Dehydrogenase 12, the Last Enzyme of Proline Catabolism in Plants.
J. Mol. Biol., 431, 2019
4ZVY
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BU of 4zvy by Molmil
Structure of human ALDH7A1 complexed with NAD+ in space group P4212
Descriptor: Alpha-aminoadipic semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Tanner, J.J.
Deposit date:2015-05-18
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1.
Biochemistry, 54, 2015
6BSN
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BU of 6bsn by Molmil
Structure of proline utilization A (PutA) with proline bound in remote sites
Descriptor: Bifunctional protein PutA, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, PROLINE, ...
Authors:Tanner, J.J, Korasick, D.A.
Deposit date:2017-12-04
Release date:2018-01-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural Basis for the Substrate Inhibition of Proline Utilization A by Proline.
Molecules, 23, 2017
4ZVX
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BU of 4zvx by Molmil
Structure of apo human ALDH7A1 in space group P4212
Descriptor: Alpha-aminoadipic semialdehyde dehydrogenase
Authors:Tanner, J.J.
Deposit date:2015-05-18
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1.
Biochemistry, 54, 2015
2RBF
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BU of 2rbf by Molmil
Structure of the ribbon-helix-helix domain of Escherichia coli PutA (PutA52) complexed with operator DNA (O2)
Descriptor: Bifunctional protein putA, DNA (5'-D(*DTP*DT*DTP*DGP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DAP*DCP*DCP*DTP*DTP*DTP*DCP*DAP*DAP*DA)-3'), DNA (5'-D(*DTP*DTP*DTP*DGP*DAP*DAP*DAP*DGP*DGP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DAP*DAP*DA)-3')
Authors:Tanner, J.J.
Deposit date:2007-09-18
Release date:2008-07-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of the transcriptional regulation of the proline utilization regulon by multifunctional PutA.
J.Mol.Biol., 381, 2008
3E2Q
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BU of 3e2q by Molmil
Crystal Structure Reduced PutA86-630 Mutant Y540S Complexed with trans-4-hydroxy-L-proline
Descriptor: 4-HYDROXYPROLINE, FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, ...
Authors:Tanner, J.J.
Deposit date:2008-08-06
Release date:2009-02-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A conserved active site tyrosine residue of proline dehydrogenase helps enforce the preference for proline over hydroxyproline as the substrate.
Biochemistry, 48, 2009
3E2S
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BU of 3e2s by Molmil
Crystal Structure Reduced PutA86-630 Mutant Y540S Complexed with L-proline
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, PROLINE, ...
Authors:Tanner, J.J.
Deposit date:2008-08-06
Release date:2009-02-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:A conserved active site tyrosine residue of proline dehydrogenase helps enforce the preference for proline over hydroxyproline as the substrate.
Biochemistry, 48, 2009
3E2R
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BU of 3e2r by Molmil
Crystal Structure PutA86-630 Mutant Y540S Complexed with L-tetrahydro-2-furoic acid
Descriptor: CITRIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, ...
Authors:Tanner, J.J.
Deposit date:2008-08-06
Release date:2009-02-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A conserved active site tyrosine residue of proline dehydrogenase helps enforce the preference for proline over hydroxyproline as the substrate.
Biochemistry, 48, 2009
3ET4
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BU of 3et4 by Molmil
Structure of Recombinant Haemophilus Influenzae E(P4) Acid Phosphatase
Descriptor: MAGNESIUM ION, Outer membrane protein P4, NADP phosphatase, ...
Authors:Tanner, J.J.
Deposit date:2008-10-06
Release date:2008-10-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of Recombinant Haemophilus Influenzae E (P4) Acid Phosphatase Reveals a New Member of the Haloacid Dehalogenase Superfamily.
Biochemistry, 46, 2007
3ET5
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BU of 3et5 by Molmil
Structure of Recombinant Haemophilus Influenzae E(P4) Acid Phosphatase Complexed with tungstate
Descriptor: MAGNESIUM ION, Outer membrane protein P4, NADP phosphatase, ...
Authors:Tanner, J.J.
Deposit date:2008-10-06
Release date:2008-10-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Recombinant Haemophilus Influenzae E (P4) Acid Phosphatase Reveals a New Member of the Haloacid Dehalogenase Superfamily.
Biochemistry, 46, 2007

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