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7P85
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BU of 7p85 by Molmil
Engineered phosphotriesterase BdPTE 10-2-C3(C59V/C227V) in complex with ethyl-4-methylbenzylphosphonate
Descriptor: FORMIC ACID, GLYCEROL, Parathion hydrolase, ...
Authors:Eichinger, A, Skerra, A.
Deposit date:2021-07-21
Release date:2022-08-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structural and Functional Analysis of a Highly Active Designed Phosphotriesterase for the Detoxification of Organophosphate Nerve Agents Reveals an Unpredicted Conformation of the Active Site Loop.
Biochemistry, 62, 2023
6I9Q
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BU of 6i9q by Molmil
Structure of the mouse CD98 heavy chain ectodomain
Descriptor: 1,2-ETHANEDIOL, 4F2 cell-surface antigen heavy chain, CHLORIDE ION
Authors:Schiefner, A, Deuschle, F.-C, Skerra, A.
Deposit date:2018-11-24
Release date:2019-04-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural differences between the ectodomains of murine and human CD98hc.
Proteins, 87, 2019
2VO9
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BU of 2vo9 by Molmil
CRYSTAL STRUCTURE OF THE ENZYMATICALLY ACTIVE DOMAIN OF THE LISTERIA MONOCYTOGENES BACTERIOPHAGE 500 ENDOLYSIN PLY500
Descriptor: L-ALANYL-D-GLUTAMATE PEPTIDASE, SULFATE ION, ZINC ION
Authors:Korndoerfer, I.P, Kanitz, A, Skerra, A.
Deposit date:2008-02-09
Release date:2008-02-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Analysis of the L-Alanoyl-D-Glutamate Endopeptidase Domain of Listeria Bacteriophage Endolysin Ply500 Reveals a New Member of the Las Peptidase Family.
Acta Crystallogr.,Sect.D, 64, 2008
3T1W
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BU of 3t1w by Molmil
Structure of the four-domain fragment Fn7B89 of oncofetal fibronectin
Descriptor: four-domain fibronectin fragment
Authors:Schiefner, A, Skerra, A.
Deposit date:2011-07-22
Release date:2012-03-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Extra-domain B in oncofetal fibronectin structurally promotes fibrillar head-to-tail dimerization of extracellular matrix protein.
J.Biol.Chem., 287, 2012
1KXO
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BU of 1kxo by Molmil
ENGINEERED LIPOCALIN DIGA16 : APO-FORM
Descriptor: DigA16
Authors:Korndoerfer, I.P, Skerra, A.
Deposit date:2002-02-01
Release date:2003-06-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural mechanism of specific ligand recognition by a lipocalin tailored for the complexation of digoxigenin.
J.Mol.Biol., 330, 2003
1LKE
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BU of 1lke by Molmil
ENGINEERED LIPOCALIN DIGA16 IN COMPLEX WITH DIGOXIGENIN
Descriptor: DIGOXIGENIN, DigA16
Authors:Korndoerfer, I.P, Skerra, A.
Deposit date:2002-04-25
Release date:2003-06-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural mechanism of specific ligand recognition by a lipocalin tailored for the complexation of digoxigenin.
J.Mol.Biol., 330, 2003
1LNM
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BU of 1lnm by Molmil
ANTICALIN DIGA16 IN COMPLEX WITH DIGITOXIGENIN
Descriptor: DIGITOXIGENIN, DigA16
Authors:Korndoerfer, I.P, Skerra, A.
Deposit date:2002-05-03
Release date:2003-06-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural mechanism of specific ligand recognition by a lipocalin tailored for the complexation of digoxigenin.
J.Mol.Biol., 330, 2003
1SG2
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BU of 1sg2 by Molmil
Crystal structure of the periplasmic chaperone Skp
Descriptor: Seventeen Kilodalton Protein
Authors:Korndorfer, I.P, Dommel, M.K, Skerra, A.
Deposit date:2004-02-23
Release date:2004-09-14
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of the periplasmic chaperone Skp suggests functional similarity with cytosolic chaperones despite differing architecture.
Nat.Struct.Mol.Biol., 11, 2004
5E9O
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BU of 5e9o by Molmil
Spirochaeta thermophila X module - CBM64 - mutant G504A
Descriptor: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, Cellulase, glycosyl hydrolase family 5, ...
Authors:Schiefner, A, Skerra, A.
Deposit date:2015-10-15
Release date:2016-03-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for cellulose binding by the type A carbohydrate-binding module 64 of Spirochaeta thermophila.
Proteins, 84, 2016
5E9P
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BU of 5e9p by Molmil
Spirochaeta thermophila X module - CBM64 - wildtype
Descriptor: Cellulase, glycosyl hydrolase family 5, TPS linker, ...
Authors:Schiefner, A, Skerra, A.
Deposit date:2015-10-15
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural basis for cellulose binding by the type A carbohydrate-binding module 64 of Spirochaeta thermophila.
Proteins, 84, 2016
6YJW
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BU of 6yjw by Molmil
Structure of Fragaria ananassa O-methyltransferase crystallized with PAS polypeptide
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, O-methyltransferase, ...
Authors:Schiefner, A, Skerra, A.
Deposit date:2020-04-05
Release date:2020-07-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Proline/alanine-rich sequence (PAS) polypeptides as an alternative to PEG precipitants for protein crystallization.
Acta Crystallogr.,Sect.F, 76, 2020
6YJX
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BU of 6yjx by Molmil
Structure of Hen egg-white lysozyme crystallized with PAS polypeptide
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
Authors:Schiefner, A, Skerra, A.
Deposit date:2020-04-05
Release date:2020-07-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Proline/alanine-rich sequence (PAS) polypeptides as an alternative to PEG precipitants for protein crystallization.
Acta Crystallogr.,Sect.F, 76, 2020
5BPK
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BU of 5bpk by Molmil
Varying binding modes of inhibitors and structural differences in the binding pockets of different gamma-glutamyltranspeptidases
Descriptor: (2S)-amino[(5S)-4,5-dihydro-1,2-oxazol-5-yl]acetic acid, 1,2-ETHANEDIOL, Gamma-glutamyltranspeptidase (Ggt)
Authors:Bolz, C, Bach, N.C, Meyer, H, Mueller, G, Dawidowski, M, Popowicz, G, Sieber, S.A, Skerra, A, Gerhard, M.
Deposit date:2015-05-28
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Varying binding modes of inhibitors and structural differences in the binding pockets of different gamma-glutamyltranspeptidases
To Be Published
4RUN
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BU of 4run by Molmil
Crystal structure of human odorant binding protein OBPIIa
Descriptor: CITRATE ANION, Odorant-binding protein 2a
Authors:Schiefner, A, Skerra, A.
Deposit date:2014-11-21
Release date:2015-04-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the human odorant binding protein, OBPIIa.
Proteins, 83, 2015
2HZQ
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BU of 2hzq by Molmil
Crystal structure of human apolipoprotein D (ApoD) in complex with progesterone
Descriptor: Apolipoprotein D, PROGESTERONE
Authors:Eichinger, A, Skerra, A.
Deposit date:2006-08-09
Release date:2007-08-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insight into the dual ligand specificity and mode of high density lipoprotein association of apolipoprotein d.
J.Biol.Chem., 282, 2007
1IVL
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BU of 1ivl by Molmil
THE DE NOVO DESIGN OF AN ANTIBODY COMBINING SITE: CRYSTALLOGRAPHIC ANALYSIS OF THE VL DOMAIN CONFIRMS THE STRUCTURAL MODEL
Descriptor: IGG-KAPPA M29B FV (LIGHT CHAIN), ISOPROPYL ALCOHOL
Authors:Essen, L.-O, Skerra, A.
Deposit date:1994-05-04
Release date:1994-08-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:The de novo design of an antibody combining site. Crystallographic analysis of the VL domain confirms the structural model.
J.Mol.Biol., 238, 1994
2HZR
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BU of 2hzr by Molmil
Crystal structure of human apolipoprotein D (ApoD)
Descriptor: Apolipoprotein D
Authors:Eichinger, A, Skerra, A.
Deposit date:2006-08-09
Release date:2007-08-14
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insight into the dual ligand specificity and mode of high density lipoprotein association of apolipoprotein d.
J.Biol.Chem., 282, 2007
1PKQ
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BU of 1pkq by Molmil
Myelin Oligodendrocyte Glycoprotein-(8-18C5) Fab-complex
Descriptor: (8-18C5) chimeric Fab, heavy chain, light chain, ...
Authors:Breithaupt, C, Schubart, A, Zander, H, Skerra, A, Huber, R, Linington, C, Jacob, U.
Deposit date:2003-06-06
Release date:2003-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein
Proc.Natl.Acad.Sci.USA, 100, 2003
1PKO
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BU of 1pko by Molmil
Myelin Oligodendrocyte Glycoprotein (MOG)
Descriptor: Myelin Oligodendrocyte Glycoprotein
Authors:Breithaupt, C, Schubart, A, Zander, H, Skerra, A, Huber, R, Linington, C, Jacob, U.
Deposit date:2003-06-06
Release date:2003-07-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein
Proc.Natl.Acad.Sci.USA, 100, 2003
7O31
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BU of 7o31 by Molmil
Crystal structure of the anti-PAS Fab 1.2 in complex with its epitope peptide and the anti-Kappa VHH domain
Descriptor: 1,2-ETHANEDIOL, PAS#1 epitope peptide, anti-Kappa VHH domain, ...
Authors:Schilz, J, Schiefner, A, Skerra, A.
Deposit date:2021-04-01
Release date:2021-07-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope.
J.Mol.Biol., 433, 2021
7O2Z
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BU of 7o2z by Molmil
Crystal structure of the anti-PAS Fab 2.2 in complex with its epitope peptide
Descriptor: CHLORIDE ION, P/A#1 epitope peptide, anti-PAS Fab 2.2 chimeric heavy chain, ...
Authors:Schilz, J, Schiefner, A, Skerra, A.
Deposit date:2021-04-01
Release date:2021-07-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope.
J.Mol.Biol., 433, 2021
7O30
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BU of 7o30 by Molmil
Crystal structure of the anti-PAS Fab 1.1 in complex with its epitope peptide
Descriptor: PAS#1 epitope peptide, anti-PAS Fab 1.1 chimeric heavy chain, anti-PAS Fab 1.1 chimeric light chain
Authors:Schilz, J, Schiefner, A, Skerra, A.
Deposit date:2021-04-01
Release date:2021-07-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope.
J.Mol.Biol., 433, 2021
7O33
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BU of 7o33 by Molmil
Crystal structure of the anti-PAS Fab 3.1 in complex with its epitope peptide
Descriptor: APSA epitope peptide, anti-PAS Fab 3.1 chimeric heavy chain, anti-PAS Fab 3.1 chimeric light chain
Authors:Schilz, J, Skerra, A.
Deposit date:2021-04-01
Release date:2021-07-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope.
J.Mol.Biol., 433, 2021
1XOV
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BU of 1xov by Molmil
The crystal structure of the listeria monocytogenes bacteriophage PSA endolysin PlyPSA
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLUTAMIC ACID, ...
Authors:Korndoerfer, I.P, Skerra, A.
Deposit date:2004-10-07
Release date:2005-10-18
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of the bacteriophage PSA endolysin reveals a unique fold responsible for specific recognition of Listeria cell walls
J.Mol.Biol., 364, 2006
4R0B
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BU of 4r0b by Molmil
Structure of dimeric human glycodelin
Descriptor: Glycodelin
Authors:Schiefner, A, Skerra, A.
Deposit date:2014-07-30
Release date:2014-12-10
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The dimeric crystal structure of the human fertility lipocalin glycodelin reveals a protein scaffold for the presentation of complex glycans.
Biochem.J., 466, 2015

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