5BPK

Varying binding modes of inhibitors and structural differences in the binding pockets of different gamma-glutamyltranspeptidases

Summary for 5BPK

Related3FNM
DescriptorGamma-glutamyltranspeptidase (Ggt), 1,2-ETHANEDIOL, (2S)-amino[(5S)-4,5-dihydro-1,2-oxazol-5-yl]acetic acid, ... (5 entities in total)
Functional Keywordsgamma-glutamyltranspeptidase, ntn-hydrolase, acivicin, proteros biostructures gmbh, hydrolase
Biological sourceHelicobacter pylori 26695
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Total number of polymer chains4
Total molecular weight133736.54
Authors
Primary citation
Bolz, C.,Bach, N.C.,Meyer, H.,Mueller, G.,Dawidowski, M.,Popowicz, G.,Sieber, S.A.,Skerra, A.,Gerhard, M.
Varying binding modes of inhibitors and structural differences in the binding pockets of different gamma-glutamyltranspeptidases
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.49 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.19130.2%1.3%1.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5bpk
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Molmil generated image of 5bpk
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Molmil generated image of 5bpk
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More Biological unit images

Molmil generated image of 5bpk
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Molmil generated image of 5bpk
rotated about x axis by 90°
Molmil generated image of 5bpk
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (5bpk.pdb1.gz [191.58 KB])
Coordinate files for Biological unit (5bpk.pdb2.gz [192.38 KB])