5BPK
Varying binding modes of inhibitors and structural differences in the binding pockets of different gamma-glutamyltranspeptidases
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Gamma-glutamyltranspeptidase (Ggt) | polymer | 379 | 40832.0 | 2 | UniProt (O25743) Pfam (PF01019) | Helicobacter pylori 26695 | |
| 2 | B, D (C, D) | Gamma-glutamyltranspeptidase (Ggt) | polymer | 225 | 24557.6 | 2 | UniProt (O25743) Pfam (PF01019) | Helicobacter pylori 26695 | |
| 3 | AA, BA, CA, DA, E... (B, A, D, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 43 | Chemie (EDO) | |||
| 4 | MA, O (D, C) | (2S)-amino[(5S)-4,5-dihydro-1,2-oxazol-5-yl]acetic acid | non-polymer | 144.1 | 2 | Chemie (4UD) | Helicobacter pylori | ||
| 5 | AB, XA, YA, ZA (D, A, C, B) | water | water | 18.0 | 958 | Chemie (HOH) |
Sequence modifications
C, D: 380 - 567 (UniProt: O25743)
| PDB | External Database | Details |
|---|---|---|
| Gly 568 | - | expression tag |
| Thr 569 | - | expression tag |
| Gly 570 | - | expression tag |
| Ser 571 | - | expression tag |
| Lys 572 | - | expression tag |
| Leu 573 | - | expression tag |
| Ala 574 | - | expression tag |
| Ala 575 | - | expression tag |
| Ala 576 | - | expression tag |
| Gln 577 | - | expression tag |
| Leu 578 | - | expression tag |
| Tyr 579 | - | expression tag |
| Thr 580 | - | expression tag |
| Arg 581 | - | expression tag |
| Ala 582 | - | expression tag |
| Ser 583 | - | expression tag |
| Gln 584 | - | expression tag |
| Pro 585 | - | expression tag |
| Glu 586 | - | expression tag |
| Leu 587 | - | expression tag |
| Ala 588 | - | expression tag |
| Pro 589 | - | expression tag |
| Glu 590 | - | expression tag |
| Asp 591 | - | expression tag |
| Pro 592 | - | expression tag |
| Glu 593 | - | expression tag |
| Asp 594 | - | expression tag |
| Leu 595 | - | expression tag |
| Glu 596 | - | expression tag |
| His 597 | - | expression tag |
| His 598 | - | expression tag |
| His 599 | - | expression tag |
| His 600 | - | expression tag |
| His 601 | - | expression tag |
| His 602 | - | expression tag |
| His 603 | - | expression tag |
| His 604 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 130779.4 | |
| Non-Polymers* | Number of molecules | 45 |
| Total formula weight | 2957.2 | |
| All* | Total formula weight | 133736.5 |
