3FNM

Crystal structure of acivicin-inhibited gamma-glutamyltranspeptidase reveals critical roles for its C-terminus in autoprocessing and catalysis

Summary for 3FNM

Entry DOI	10.2210/pdb3fnm/pdb
Related	2NQO 2QMG
Descriptor	Gamma-glutamyltranspeptidase (Ggt) Large subunit, Gamma-glutamyltranspeptidase (Ggt) Small subunit, (2S)-AMINO[(5S)-3-CHLORO-4,5-DIHYDROISOXAZOL-5-YL]ACETIC ACID, ... (4 entities in total)
Functional Keywords	ntn-hydrolase, glutamyltranspeptidase, transferase
Biological source	Helicobacter pylori (Campylobacter pylori) More
Total number of polymer chains	4
Total formula weight	122332.28
Authors	Williams, K.,Cullati, S.,Sand, A.,Biterova, E.I.,Barycki, J.J. (deposition date: 2008-12-25, release date: 2009-05-19, Last modification date: 2017-11-01)
Primary citation	Williams, K.,Cullati, S.,Sand, A.,Biterova, E.I.,Barycki, J.J. Crystal Structure of Acivicin-Inhibited gamma-Glutamyltranspeptidase Reveals Critical Roles for Its C-Terminus in Autoprocessing and Catalysis. Biochemistry, 48:2459-2467, 2009 Cited by PubMed: 19256527 DOI: 10.1021/bi8014955 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation