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5LDY
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BU of 5ldy by Molmil
Structure of Yersinia pseudotuberculosis InvD
Descriptor: Ig domain protein group 1 domain protein, PHOSPHATE ION
Authors:Sadana, P, Scrima, A.
Deposit date:2016-06-28
Release date:2017-06-14
Last modified:2020-06-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The invasin D protein from Yersinia pseudotuberculosis selectively binds the Fab region of host antibodies and affects colonization of the intestine
J.Biol.Chem., 2018
2HF9
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BU of 2hf9 by Molmil
Crystal structure of HypB from Methanocaldococcus jannaschii in the triphosphate form
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Probable hydrogenase nickel incorporation protein hypB, ...
Authors:Gasper, R, Scrima, A, Wittinghofer, A.
Deposit date:2006-06-23
Release date:2006-07-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into HypB, a GTP-binding protein that regulates metal binding.
J.Biol.Chem., 281, 2006
2HF8
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BU of 2hf8 by Molmil
Crystal structure of HypB from Methanocaldococcus jannaschii in the triphosphate form, in complex with zinc
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Probable hydrogenase nickel incorporation protein hypB, ...
Authors:Gasper, R, Scrima, A, Wittinghofer, A.
Deposit date:2006-06-23
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into HypB, a GTP-binding protein that regulates metal binding.
J.Biol.Chem., 281, 2006
2NTY
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BU of 2nty by Molmil
Rop4-GDP-PRONE8
Descriptor: Emb|CAB41934.1, GUANOSINE-5'-DIPHOSPHATE, Rac-like GTP-binding protein ARAC5
Authors:Thomas, C, Fricke, I, Scrima, A, Berken, A, Wittinghofer, A.
Deposit date:2006-11-08
Release date:2007-01-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Evidence for a Common Intermediate in Small G Protein-GEF Reactions
Mol.Cell, 25, 2007
2NTX
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BU of 2ntx by Molmil
Prone8
Descriptor: Emb|CAB41934.1
Authors:Thomas, C, Fricke, I, Scrima, A, Berken, A, Wittinghofer, A.
Deposit date:2006-11-08
Release date:2007-01-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Evidence for a Common Intermediate in Small G Protein-GEF Reactions
Mol.Cell, 25, 2007
5NPV
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BU of 5npv by Molmil
Structure of human ATG5-ATG16L1(ATG5BD) complex (I4)
Descriptor: Autophagy protein 5, Autophagy-related protein 16-1
Authors:Archna, A, Scrima, A.
Deposit date:2017-04-19
Release date:2017-10-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Identification, biochemical characterization and crystallization of the central region of human ATG16L1.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5NPW
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BU of 5npw by Molmil
Structure of human ATG5-ATG16L1(ATG5BD) complex (C2)
Descriptor: Autophagy protein 5, Autophagy-related protein 16-1
Authors:Archna, A, Scrima, A.
Deposit date:2017-04-19
Release date:2017-10-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Identification, biochemical characterization and crystallization of the central region of human ATG16L1.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5OJY
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BU of 5ojy by Molmil
Co-complex structure of regulator protein 2 (PamR2) with pamamycin 607 from Streptomyces alboniger
Descriptor: CITRIC ACID, GLYCEROL, Pamamycin 607, ...
Authors:Schmelz, S, Rebets, Y, Luzhetskyy, A, Scrima, A.
Deposit date:2017-07-24
Release date:2018-04-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Design, development and application of whole-cell based antibiotic-specific biosensor.
Metab. Eng., 47, 2018
5OJX
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BU of 5ojx by Molmil
Crystal structure of regulator protein 2 (PamR2) from the pamamycin biosynthetic gene cluster of Streptomyces alboniger
Descriptor: TetR family transcription regulator
Authors:Schmelz, S, Rebets, Y, Luzhetskyy, A, Scrima, A.
Deposit date:2017-07-24
Release date:2018-04-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design, development and application of whole-cell based antibiotic-specific biosensor.
Metab. Eng., 47, 2018
3CP8
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BU of 3cp8 by Molmil
Crystal structure of GidA from Chlorobium tepidum
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, tRNA uridine 5-carboxymethylaminomethyl modification enzyme gidA
Authors:Meyer, S, Scrima, A, Versees, W, Wittinghofer, A.
Deposit date:2008-03-31
Release date:2008-06-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate
J.Mol.Biol., 380, 2008
5NUV
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BU of 5nuv by Molmil
Structure of the WD40-domain of human ATG16L1
Descriptor: (R,R)-2,3-BUTANEDIOL, Autophagy-related protein 16-1
Authors:Bajagic, M, Scrima, A.
Deposit date:2017-05-02
Release date:2017-07-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of the WD40-domain of human ATG16L1.
Protein Sci., 26, 2017
5NTB
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BU of 5ntb by Molmil
Streptomyces papain inhibitor (SPI)
Descriptor: Papain inhibitor, SULFATE ION
Authors:Schmelz, S, Juettner, N.E, Fuchsbauer, H.L, Scrima, A.
Deposit date:2017-04-27
Release date:2018-03-07
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Illuminating structure and acyl donor sites of a physiological transglutaminase substrate from Streptomyces mobaraensis.
Protein Sci., 27, 2018
5N40
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BU of 5n40 by Molmil
Structure of Yersinia pseudotuberculosis adhesin InvE
Descriptor: DI(HYDROXYETHYL)ETHER, Putative invasin
Authors:Sadana, P, Scrima, A.
Deposit date:2017-02-09
Release date:2017-04-12
Last modified:2017-06-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the Y. pseudotuberculosis adhesin InvasinE.
Protein Sci., 26, 2017
4A11
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BU of 4a11 by Molmil
Structure of the hsDDB1-hsCSA complex
Descriptor: DNA DAMAGE-BINDING PROTEIN 1, DNA EXCISION REPAIR PROTEIN ERCC-8
Authors:Bohm, K, Scrima, A, Fischer, E.S, Gut, H, Thomae, N.H.
Deposit date:2011-09-13
Release date:2011-12-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011
4BJ6
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BU of 4bj6 by Molmil
Crystal structure Rif2 in complex with the C-terminal domain of Rap1 (Rap1-RCT)
Descriptor: DNA-BINDING PROTEIN RAP1, RAP1-INTERACTING FACTOR 2, SULFATE ION
Authors:Shi, T, Bunker, R.D, Gut, H, Scrima, A, Thoma, N.H.
Deposit date:2013-04-16
Release date:2013-06-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions
Cell(Cambridge,Mass.), 153, 2013
4BJ5
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BU of 4bj5 by Molmil
Crystal structure of Rif2 in complex with the C-terminal domain of Rap1 (Rap1-RCT)
Descriptor: DNA-BINDING PROTEIN RAP1, PROTEIN RIF2, SULFATE ION
Authors:Shi, T, Bunker, R.D, Gut, H, Scrima, A, Thoma, N.H.
Deposit date:2013-04-16
Release date:2013-06-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions
Cell(Cambridge,Mass.), 153, 2013
4BJT
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BU of 4bjt by Molmil
Crystal structure of the Rap1 C-terminal domain (Rap1-RCT) in complex with the Rap1 binding module of Rif1 (Rif1-RBM)
Descriptor: 1,2-ETHANEDIOL, DNA-BINDING PROTEIN RAP1, TELOMERE LENGTH REGULATOR PROTEIN RIF1
Authors:Shi, T, Bunker, R.D, Gut, H, Scrima, A, Thoma, N.H.
Deposit date:2013-04-19
Release date:2013-06-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions
Cell(Cambridge,Mass.), 153, 2013
4BJS
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BU of 4bjs by Molmil
Crystal structure of the Rif1 C-terminal domain (Rif1-CTD) from Saccharomyces cerevisiae
Descriptor: TELOMERE LENGTH REGULATOR PROTEIN RIF1
Authors:Bunker, R.D, Shi, T, Gut, H, Scrima, A, Thoma, N.H.
Deposit date:2013-04-19
Release date:2013-06-19
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions
Cell(Cambridge,Mass.), 153, 2013
4BJ1
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BU of 4bj1 by Molmil
Crystal structure of Saccharomyces cerevisiae RIF2
Descriptor: CHLORIDE ION, PROTEIN RIF2
Authors:Shi, T, Bunker, R.D, Gut, H, Scrima, A, Thoma, N.H.
Deposit date:2013-04-15
Release date:2013-06-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions
Cell(Cambridge,Mass.), 153, 2013
4A0K
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BU of 4a0k by Molmil
STRUCTURE OF DDB1-DDB2-CUL4A-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX
Descriptor: 12 BP DNA, 12 BP THF CONTAINING DNA, CULLIN-4A, ...
Authors:Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H.
Deposit date:2011-09-09
Release date:2011-12-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (5.93 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011
4A0L
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BU of 4a0l by Molmil
Structure of DDB1-DDB2-CUL4B-RBX1 bound to a 12 bp abasic site containing DNA-duplex
Descriptor: 12 BP DNA DUPLEX, 12 BP THF CONTAINING DNA DUPLEX, CULLIN-4B, ...
Authors:Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H.
Deposit date:2011-09-09
Release date:2011-12-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (7.4 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011
7NBW
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BU of 7nbw by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with a pyridin agonist
Descriptor: Transcriptional regulator MvfR, ~{N}-[3-(4-fluorophenyl)prop-2-ynyl]-2-(trifluoromethyl)pyridin-4-amine
Authors:Schmelz, S, Blankenfeldt, W.
Deposit date:2021-01-28
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Divergent synthesis and biological evaluation of 2-(trifluoromethyl)pyridines as virulence-attenuating inverse agonists targeting PqsR.
Eur.J.Med.Chem., 226, 2021
6YIZ
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BU of 6yiz by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with triazolo-pyridine inverse agonist A
Descriptor: 7-oxidanylidene-8-[2-(4-sulfonaphthalen-1-yl)hydrazinyl]-8~{H}-naphthalene-1,3-disulfonic acid, MAGNESIUM ION, Transcriptional regulator MvfR, ...
Authors:Schmelz, S, Blankenfeldt, W.
Deposit date:2020-04-01
Release date:2021-04-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.163 Å)
Cite:A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms.
Adv Sci, 8, 2021
8QPY
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BU of 8qpy by Molmil
Solution NMR structure of the peptidyl carrier domain TomAPCP from the Tomaymycin non-ribosomal peptide synthetase
Descriptor: Carrier protein TomAPCP
Authors:Karanth, M.N, Kirkpatrick, J.P, Carlomagno, T.
Deposit date:2023-10-03
Release date:2024-06-26
Last modified:2024-07-03
Method:SOLUTION NMR
Cite:The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain.
Sci Adv, 10, 2024
8QRX
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BU of 8qrx by Molmil
Solution NMR structure of the peptidyl carrier domain TomAPCP from the Tomaymycin non-ribosomal peptide synthetase in its substrate-loaded state
Descriptor: TomAPCP substrate-loaded from the Tomaymycin non-ribosomal peptide synthetase
Authors:Karanth, M.N, Kirkpatrick, J.P, Carlomagno, T.
Deposit date:2023-10-09
Release date:2024-06-26
Last modified:2024-07-03
Method:SOLUTION NMR
Cite:The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain.
Sci Adv, 10, 2024

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