470D
| CRYSTAL STRUCTURE AND IMPROVED ANTISENSE PROPERTIES OF 2'-O-(2-METHOXYETHYL)-RNA | Descriptor: | MAGNESIUM ION, RNA (5'-R(*(C43)P*(G48)P*(C43)P*(G48)P*(A44)P*(A44)P*(U36)P*(U36)P*(C43)P*(G48)P*(C43)P*(G48))-3') | Authors: | Teplova, M, Minasov, G, Tereshko, V, Inamati, G, Cook, P.D, Egli, M. | Deposit date: | 1999-04-29 | Release date: | 1999-05-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA. Nat.Struct.Biol., 6, 1999
|
|
7VQF
| Phenol binding protein, MopR | Descriptor: | ACETATE ION, PHENOL, Phenol sensing regulator, ... | Authors: | Singh, J, Ray, S, Anand, R. | Deposit date: | 2021-10-19 | Release date: | 2022-09-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Phenol sensing in nature is modulated via a conformational switch governed by dynamic allostery. J.Biol.Chem., 298, 2022
|
|
2Q85
| |
1DJ8
| |
2R7B
| Crystal Structure of the Phosphoinositide-dependent Kinase-1 (PDK-1)Catalytic Domain bound to a dibenzonaphthyridine inhibitor | Descriptor: | 10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine, 3-phosphoinositide-dependent protein kinase 1, SULFATE ION | Authors: | Olland, A.M. | Deposit date: | 2007-09-07 | Release date: | 2008-09-09 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Discovery of Dibenzo[c,f][2,7]naphthyridines as Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 Inhibitors. J.Med.Chem., 50, 2007
|
|
2ZM3
| Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor | Descriptor: | (4Z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]amino}methylidene)isoquinoline-1,3(2H,4H)-dione, Insulin-like growth factor 1 receptor | Authors: | Xu, W, Mayer, S.C, Boschelli, F, Johnson, M, Dwyer, B. | Deposit date: | 2008-04-10 | Release date: | 2008-06-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment Bioorg.Med.Chem.Lett., 18, 2008
|
|
2HH0
| |