2Q85

Crystal Structure of E. Coli Mur B bound to a Naphthyl Tetronic Acid inihibitor

Summary for 2Q85

DescriptorUDP-N-acetylenolpyruvoylglucosamine reductase, (5Z)-3-(4-CHLOROPHENYL)-4-HYDROXY-5-(1-NAPHTHYLMETHYLENE)FURAN-2(5H)-ONE, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
Functional Keywordsoxidoreductase
Biological sourceEscherichia coli
Cellular locationCytoplasm (Probable) P08373
Total number of polymer chains1
Total molecular weight39026.24
Authors
Chopra, R.,Bard, J.,Svenson, K.,Mansour, T. (deposition date: 2007-06-08, release date: 2007-06-26, Last modification date: 2011-07-13)
Primary citation
Mansour, T.,Caulfield, C.E.,Rasmussen, B.,Chopra, R.,Krishnamurthy, G.,Morris, K.M.,Svenson, K.,Bard, J.,Smeltzer, C.,Naughton, S.,Antane, S.,Yang, Y.,Severin, A.,Quagliato, D.,Petersen, P.J.,Singh, G.
Crystal Structure of E. Coli Mur B bound to a napthyl tetronic acid inhibitor
TO BE PUBLISHED,
Experimental method
X-RAY DIFFRACTION (2.51 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers0.163401.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2q85
no rotation
Molmil generated image of 2q85
rotated about x axis by 90°
Molmil generated image of 2q85
rotated about y axis by 90°