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6BUW
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BU of 6buw by Molmil
Thermus thermophilus 70S complex containing 16S G299A ram mutation and empty A site.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2017-12-11
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.
Nucleic Acids Res., 47, 2019
4YY3
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BU of 4yy3 by Molmil
30S ribosomal subunit- HigB complex
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Schureck, M.A, Maehigashi, T, Dunham, C.M.
Deposit date:2015-03-23
Release date:2016-07-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:mRNA bound to the 30S subunit is a HigB toxin substrate.
Rna, 22, 2016
6BZ6
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BU of 6bz6 by Molmil
Thermus thermophilus 70S complex containing 16S G347U ram mutation and empty A site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2017-12-22
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.
Nucleic Acids Res., 47, 2019
6BZ8
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BU of 6bz8 by Molmil
Thermus thermophilus 70S containing 16S G347U point mutation and near-cognate ASL Leucine in A site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2017-12-22
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.74 Å)
Cite:Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.
Nucleic Acids Res., 47, 2019
6BZ7
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BU of 6bz7 by Molmil
Thermus thermophilus 70S containing 16S G299A point mutation and near-cognate ASL Leucine in A site.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2017-12-22
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.68 Å)
Cite:Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.
Nucleic Acids Res., 47, 2019
4YZV
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BU of 4yzv by Molmil
Precleavage 70S structure of the P. vulgaris HigB deltaH92 toxin bound to the ACA codon
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Schureck, M.A, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
Deposit date:2015-03-25
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YPB
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BU of 4ypb by Molmil
Precleavage 70S structure of the P. vulgaris HigB DeltaH92 toxin bound to the AAA codon
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Schureck, M.A, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
Deposit date:2015-03-12
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
6OSI
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BU of 6osi by Molmil
Unmodified tRNA(Pro) bound to Thermus thermophilus 70S (near cognate)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
Deposit date:2019-05-01
Release date:2020-10-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (4.14 Å)
Cite:Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6OXI
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BU of 6oxi by Molmil
Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (UAA)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.495 Å)
Cite:Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
6OTR
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BU of 6otr by Molmil
Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (AAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Pavelich, I.P, Hoffer, E.D, Maehigashi, T, Dunham, C.M.
Deposit date:2019-05-03
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
6OXA
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BU of 6oxa by Molmil
Dimeric E.coli YoeB bound to Thermus thermophilus 70S pre-cleavage (AAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
6NY6
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BU of 6ny6 by Molmil
Structure of dimeric Escherichia coli toxin YoeB bound to the Thermus thermophilus 30S ribosome
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M.
Deposit date:2019-02-11
Release date:2019-08-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.74 Å)
Cite:Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
6NUO
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BU of 6nuo by Molmil
Modified tRNA(Pro) bound to Thermus thermophilus 70S (cognate)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
Deposit date:2019-02-01
Release date:2020-10-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6NWY
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BU of 6nwy by Molmil
Modified tRNA(Pro) bound to Thermus thermophilus 70S (near-cognate)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
Deposit date:2019-02-07
Release date:2020-10-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6NSH
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BU of 6nsh by Molmil
Modified ASL proline bound to Thermus thermophilus 70S (near-cognate)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M.
Deposit date:2019-01-24
Release date:2020-10-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.397 Å)
Cite:Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6NTA
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BU of 6nta by Molmil
Modified ASL proline bound to Thermus thermophilus 70S (cognate)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M.
Deposit date:2019-01-28
Release date:2020-10-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6O3M
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BU of 6o3m by Molmil
Unmodified tRNA(Pro) bound to Thermus thermophilus 70S (cognate)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
Deposit date:2019-02-26
Release date:2020-10-14
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.97 Å)
Cite:Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
4MCT
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BU of 4mct by Molmil
P. vulgaris HIGBA structure, crystal form 1
Descriptor: Antidote protein, Killer protein
Authors:Schureck, M.A, Maehigashi, T, Dunham, C.M.
Deposit date:2013-08-21
Release date:2013-12-11
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the Proteus vulgaris HigB-(HigA)2-HigB Toxin-Antitoxin Complex.
J.Biol.Chem., 289, 2014
4MCX
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BU of 4mcx by Molmil
P. vulgaris HIGBA structure, crystal form 2
Descriptor: Antidote protein, Killer protein
Authors:Schureck, M.A, Maehigashi, T, Dunham, C.M.
Deposit date:2013-08-21
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the Proteus vulgaris HigB-(HigA)2-HigB Toxin-Antitoxin Complex.
J.Biol.Chem., 289, 2014
4PX8
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BU of 4px8 by Molmil
Structure of P. vulgaris HigB toxin
Descriptor: CHLORIDE ION, Killer protein
Authors:Schureck, M.A, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
Deposit date:2014-03-22
Release date:2015-10-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
7KE0
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BU of 7ke0 by Molmil
HIV-1 Integrase catalytic core domain complexed with allosteric inhibitor STP03-0404
Descriptor: (2S)-tert-butoxy{4-(4-chlorophenyl)-2,3,6-trimethyl-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}acetic acid, Integrase
Authors:Lindenberger, J.J, Kvaratskhelia, M.
Deposit date:2020-10-09
Release date:2021-09-22
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site.
Plos Pathog., 17, 2021
4TUE
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BU of 4tue by Molmil
Crystal structure of ASL-SufJ bound to Codon ACC-U on the Ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fagan, C.E, Dunham, C.M.
Deposit date:2014-06-24
Release date:2015-05-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural insights into translational recoding by frameshift suppressor tRNASufJ.
Rna, 20, 2014
4TUD
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BU of 4tud by Molmil
Crystal structure of ASL-SufJ bound to Codon ACC-C on the Ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fagan, C.E, Dunham, C.M.
Deposit date:2014-06-24
Release date:2015-05-13
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural insights into translational recoding by frameshift suppressor tRNASufJ.
Rna, 20, 2014
4TUB
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BU of 4tub by Molmil
Crystal structure of tRNA-Thr bound to Codon ACC-C on the Ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fagan, C.E, Dunham, C.M.
Deposit date:2014-06-24
Release date:2015-05-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural insights into translational recoding by frameshift suppressor tRNASufJ.
Rna, 20, 2014
4TUA
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BU of 4tua by Molmil
Crystal structure of ASL-Thr bound to Codon ACC-A on the Ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fagan, C.E, Dunham, C.M.
Deposit date:2014-06-24
Release date:2015-05-13
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural insights into translational recoding by frameshift suppressor tRNASufJ.
Rna, 20, 2014

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