8JN2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jn2 by Molmil](/molmil-images/mine/8jn2) | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-115 Fab at 4 deg C (subparticle LLR-LRR) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody DENV-115 heavy chain, ... | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | Deposit date: | 2023-06-06 | Release date: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants To Be Published
|
|
8JN1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jn1 by Molmil](/molmil-images/mine/8jn1) | Cryo-EM structure of dengue virus serotype 3 strain EHIE46200Y19 in complex with human antibody DENV-115 IgG at 4 deg C (subparticle LLR-LRR) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein (Fragment), Human antibody DENV-115 heavy chain, ... | Authors: | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | Deposit date: | 2023-06-06 | Release date: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants To Be Published
|
|
6IDI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6idi by Molmil](/molmil-images/mine/6idi) | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 8.0. | Descriptor: | Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... | Authors: | Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. | Deposit date: | 2018-09-10 | Release date: | 2018-12-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody. Structure, 27, 2019
|
|
6IDK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6idk by Molmil](/molmil-images/mine/6idk) | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 5.0 (Class I particle) | Descriptor: | Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... | Authors: | Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. | Deposit date: | 2018-09-10 | Release date: | 2018-12-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (25 Å) | Cite: | Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody. Structure, 27, 2019
|
|
6IDL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6idl by Molmil](/molmil-images/mine/6idl) | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 5.0 (Class II particle) | Descriptor: | Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... | Authors: | Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. | Deposit date: | 2018-09-10 | Release date: | 2018-12-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (25 Å) | Cite: | Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody. Structure, 27, 2019
|
|
7BUA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bua by Molmil](/molmil-images/mine/7bua) | Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 8.0 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, SIgN-3C Fab heavy chain, ... | Authors: | Zhang, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Lok, S.M. | Deposit date: | 2020-04-06 | Release date: | 2020-05-13 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | A Human Antibody Neutralizes Different Flaviviruses by Using Different Mechanisms. Cell Rep, 31, 2020
|
|
7BUD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bud by Molmil](/molmil-images/mine/7bud) | Cryo-EM structure of Dengue virus serotype 2 complexed with Fab SIgN-3C at pH 8.0 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dengue virus serotype 2 E protein, ... | Authors: | Zhang, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Lok, S.M. | Deposit date: | 2020-04-06 | Release date: | 2020-05-13 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | A Human Antibody Neutralizes Different Flaviviruses by Using Different Mechanisms. Cell Rep, 31, 2020
|
|
7BUE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bue by Molmil](/molmil-images/mine/7bue) | Cryo-EM structure of Dengue virus serotype 2 complexed with Fab SIgN-3C at pH 5.0 | Descriptor: | Dengue serotype 2 E protein ectodomain, SIgN-3C Fab heavy chain, SIgN-3C Fab light chain | Authors: | Zhang, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Lok, S.M. | Deposit date: | 2020-04-06 | Release date: | 2020-05-13 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | A Human Antibody Neutralizes Different Flaviviruses by Using Different Mechanisms. Cell Rep, 31, 2020
|
|
7BU8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bu8 by Molmil](/molmil-images/mine/7bu8) | Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 6.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, SIgN-3C Fab heavy chain, ... | Authors: | Zhang, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Lok, S.M. | Deposit date: | 2020-04-05 | Release date: | 2020-05-13 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | A Human Antibody Neutralizes Different Flaviviruses by Using Different Mechanisms. Cell Rep, 31, 2020
|
|
7BUB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bub by Molmil](/molmil-images/mine/7bub) | Cryo-EM structure of Dengue virus serotype 2 complexed with Fab SIgN-3C at pH 6.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dengue virus serotype 2 M protein, ... | Authors: | Zhang, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Lok, S.M. | Deposit date: | 2020-04-06 | Release date: | 2020-05-13 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | A Human Antibody Neutralizes Different Flaviviruses by Using Different Mechanisms. Cell Rep, 31, 2020
|
|
7BUF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7buf by Molmil](/molmil-images/mine/7buf) | Cryo-EM structure of Dengue virus serotype 2 complexed with SIgN-3C IgG | Descriptor: | Dengue virus serotype 2 E protein, Dengue virus serotype 2 M protein, SIgN-3C IgG heavy chain, ... | Authors: | Zhang, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Lok, S.M. | Deposit date: | 2020-04-06 | Release date: | 2020-05-13 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (6.1 Å) | Cite: | A Human Antibody Neutralizes Different Flaviviruses by Using Different Mechanisms. Cell Rep, 31, 2020
|
|
7CW3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cw3 by Molmil](/molmil-images/mine/7cw3) | Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG (subregion around icosahedral 2-fold vertex) | Descriptor: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | Authors: | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | Deposit date: | 2020-08-27 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (9.4 Å) | Cite: | Structural basis of Chikungunya virus inhibition by monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
5IZ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5iz7 by Molmil](/molmil-images/mine/5iz7) | Cryo-EM structure of thermally stable Zika virus strain H/PF/2013 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, structural protein E, structural protein M | Authors: | Kostyuchenko, V.A, Zhang, S, Fibriansah, G, Lok, S.M. | Deposit date: | 2016-03-25 | Release date: | 2016-05-25 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of the thermally stable Zika virus Nature, 533, 2016
|
|
6LNU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lnu by Molmil](/molmil-images/mine/6lnu) | Cryo-EM structure of immature Zika virus | Descriptor: | Genome polyprotein | Authors: | Tan, T.Y, Fibriansah, G, Kostyuchenko, V.A, Ng, T.S, Lim, X.X, Lim, X.N, Shi, J, Morais, M.C, Corti, D, Lok, S.M. | Deposit date: | 2020-01-02 | Release date: | 2020-02-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Capsid protein structure in Zika virus reveals the flavivirus assembly process. Nat Commun, 11, 2020
|
|
6LNT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lnt by Molmil](/molmil-images/mine/6lnt) | Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab | Descriptor: | Envelope protein, Fab DV62.5 heavy-chain variable region, Fab DV62.5 light-chain variable region, ... | Authors: | Tan, T.Y, Fibriansah, G, Kostyuchenko, V.A, Ng, T.S, Lim, X.X, Lim, X.N, Shi, J, Morais, M.C, Corti, D, Lok, S.M. | Deposit date: | 2020-01-02 | Release date: | 2020-02-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Capsid protein structure in Zika virus reveals the flavivirus assembly process. Nat Commun, 11, 2020
|
|
3ZKO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zko by Molmil](/molmil-images/mine/3zko) | The structure of ''breathing'' dengue virus. | Descriptor: | ENVELOPE GLYCOPROTEIN | Authors: | Fibriansah, G, Ng, T.S, Kostyuchenko, V.A, Lee, S, Wang, J, Lok, S.M. | Deposit date: | 2013-01-24 | Release date: | 2013-05-15 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (13.7 Å) | Cite: | Structural Changes of Dengue Virus When Exposed to 37 Degrees C. J.Virol., 87, 2013
|
|
5A1Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5a1z by Molmil](/molmil-images/mine/5a1z) | Cryo-EM structure of Dengue virus serotype 2 strain PVP94-07 complexed with human antibody 2D22 Fab at 37 degrees C | Descriptor: | ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - LIGHT CHAIN, ENVELOPE PROTEIN, ... | Authors: | Fibriansah, G, Ibarra, K.D, Ng, T.S, Smith, S.A, Tan, J.L, Lim, X.N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe Jr, J.E, Lok, S.M. | Deposit date: | 2015-05-06 | Release date: | 2015-07-15 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Science, 349, 2015
|
|
4B03
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4b03 by Molmil](/molmil-images/mine/4b03) | 6A Electron cryomicroscopy structure of immature Dengue virus serotype 1 | Descriptor: | DENGUE VIRUS 1 E PROTEIN, DENGUE VIRUS 1 PRM PROTEIN | Authors: | Kostyuchenko, V.A, Zhang, Q, Tan, L.C, Ng, T.S, Lok, S.M. | Deposit date: | 2012-06-28 | Release date: | 2013-06-05 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Immature and Mature Dengue Serotype 1 Virus Structures Provide Insight Into the Maturation Process. J.Virol., 87, 2013
|
|
7V3F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v3f by Molmil](/molmil-images/mine/7v3f) | DENV2_NGC_Fab_C10 28degree (1Fab:3E) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | Deposit date: | 2021-08-10 | Release date: | 2021-12-29 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics. Cell, 184, 2021
|
|
7V3G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v3g by Molmil](/molmil-images/mine/7v3g) | DENV2_NGC_Fab_C10 28degrees (2Fab:3E) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | Deposit date: | 2021-08-10 | Release date: | 2021-12-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics. Cell, 184, 2021
|
|
7V3H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v3h by Molmil](/molmil-images/mine/7v3h) | DENV2_NGC_Fab_C10 28degrees (3Fab:3E) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C10 IgG heavy chain variable region, ... | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | Deposit date: | 2021-08-10 | Release date: | 2021-12-29 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics. Cell, 184, 2021
|
|
7V3I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v3i by Molmil](/molmil-images/mine/7v3i) | DENV2_NGC_Fab_C10 4degrees (3Fab:3E) | Descriptor: | Envelope protein E, Fab_C10_heavy_chain, Fab_C10_light_chain, ... | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | Deposit date: | 2021-08-10 | Release date: | 2021-12-29 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics. Cell, 184, 2021
|
|
7V3J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v3j by Molmil](/molmil-images/mine/7v3j) | DENV2:F(ab')2-local | Descriptor: | Envelope protein E, Fab_C10_heavy_chain, Fab_C10_light_chain, ... | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | Deposit date: | 2021-08-10 | Release date: | 2021-12-29 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics. Cell, 184, 2021
|
|
3IXY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ixy by Molmil](/molmil-images/mine/3ixy) | The pseudo-atomic structure of dengue immature virus in complex with Fab fragments of the anti-fusion loop antibody E53 | Descriptor: | E53 Fab Fragment (chain H), E53 Fab Fragment (chain L), Envelope protein E, ... | Authors: | Cherrier, M.V, Kaufmann, B, Nybakken, G.E, Lok, S.M, Warren, J.T, Nelson, C.A, Kostyuchenko, V.A, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Diamond, M.S, Rossmann, M.G, Fremont, D.H. | Deposit date: | 2009-02-26 | Release date: | 2009-10-27 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (23 Å) | Cite: | Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody Embo J., 28, 2009
|
|
3J31
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3j31 by Molmil](/molmil-images/mine/3j31) | Life in the extremes: atomic structure of Sulfolobus Turreted Icosahedral Virus | Descriptor: | A223 penton base, A55 membrane protein, C381 turret protein, ... | Authors: | Veesler, D, Ng, T.S, Sendamarai, A.K, Eilers, B.J, Lawrence, C.M, Lok, S.M, Young, M.J, Johnson, J.E, Fu, C.-Y. | Deposit date: | 2013-02-18 | Release date: | 2013-05-01 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Atomic structure of the 75 MDa extremophile Sulfolobus turreted icosahedral virus determined by CryoEM and X-ray crystallography. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|