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6W4C
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BU of 6w4c by Molmil
Crystal structure of HAO1 in complex with indazole acid inhibitor - compound 5
Descriptor: 5-[[3-[3-(dimethylamino)-1,2,4-oxadiazol-5-yl]-2-oxidanyl-phenyl]methylamino]-2~{H}-indazole-3-carboxylic acid, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 1
Authors:Ferguson, A.D.
Deposit date:2020-03-10
Release date:2021-05-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening.
J.Med.Chem., 64, 2021
2YKG
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BU of 2ykg by Molmil
Structural insights into RNA recognition by RIG-I
Descriptor: 5'-R(*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP)-3', PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, SULFATE ION, ...
Authors:Luo, D, Pyle, A.M.
Deposit date:2011-05-27
Release date:2011-10-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights Into RNA Recognition by Rig-I.
Cell(Cambridge,Mass.), 147, 2011
6HJS
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BU of 6hjs by Molmil
Crystal structure of glutathione transferase Omega 1C from Trametes versicolor
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLUTATHIONE, Uncharacterized protein
Authors:Schwartz, M, Favier, F, Didierjean, C.
Deposit date:2018-09-04
Release date:2019-09-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.612 Å)
Cite:Diversity of Omega Glutathione Transferases in mushroom-forming fungi revealed by phylogenetic, transcriptomic, biochemical and structural approaches.
Fungal Genet Biol., 2021
3KJL
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BU of 3kjl by Molmil
Sgf11:Sus1 complex
Descriptor: Protein SUS1, SAGA-associated factor 11
Authors:Stewart, M, Ellisdon, A.M.
Deposit date:2009-11-03
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1.
J.Biol.Chem., 285, 2010
3KIK
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BU of 3kik by Molmil
Sgf11:Sus1 complex
Descriptor: Protein SUS1, SAGA-associated factor 11
Authors:Stewart, M, Ellisdon, A.M.
Deposit date:2009-11-02
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1
J.Biol.Chem., 285, 2010
4AY2
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BU of 4ay2 by Molmil
Capturing 5' tri-phosphorylated RNA duplex by RIG-I
Descriptor: 5'-R-PPP(GP*GP*CP*GP*CP*GP*GP*CP*UP*UP*CP*GP*GP*CP *CP*GP*CP*GP*CP*C)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Luo, D, Pyle, A.M.
Deposit date:2012-06-17
Release date:2012-10-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor Rig-I.
Structure, 20, 2012
6HG7
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BU of 6hg7 by Molmil
Crystal structure of a collagen II fragment containing the binding site of PEDF and COMP, (POG)4-LKG HRG FTG LQG-POG(4)
Descriptor: Collagen alpha-1(II) chain, SULFATE ION
Authors:Gebauer, J.M, Koehler, A, Dietmar, H, Gompert, M, Neundorf, I, Zaucke, F, Koch, M, Baumann, U.
Deposit date:2018-08-22
Release date:2018-12-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1 Å)
Cite:COMP and TSP-4 interact specifically with the novel GXKGHR motif only found in fibrillar collagens.
Sci Rep, 8, 2018
6SR9
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BU of 6sr9 by Molmil
Crystal structure of glutathione transferase Omega 2C from Trametes versicolor in complex with oxyresveratrol
Descriptor: GLUTATHIONE, Uncharacterized protein, trans-oxyresveratrol
Authors:Schwartz, M, Favier, F, Didierjean, C.
Deposit date:2019-09-05
Release date:2020-09-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.845 Å)
Cite:Diversity of Omega Glutathione Transferases in mushroom-forming fungi revealed by phylogenetic, transcriptomic, biochemical and structural approaches.
Fungal Genet Biol., 148, 2021
6SR8
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BU of 6sr8 by Molmil
Crystal structure of glutathione transferase Omega 2C from Trametes versicolor
Descriptor: GLUTATHIONE, Uncharacterized protein
Authors:Schwartz, M, Favier, F, Didierjean, C.
Deposit date:2019-09-05
Release date:2020-09-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Diversity of Omega Glutathione Transferases in mushroom-forming fungi revealed by phylogenetic, transcriptomic, biochemical and structural approaches.
Fungal Genet Biol., 148, 2021
6SRB
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BU of 6srb by Molmil
Crystal structure of glutathione transferase Omega 3C from Trametes versicolor
Descriptor: GLUTATHIONE, Uncharacterized protein
Authors:Schwartz, M, Favier, F, Didierjean, C.
Deposit date:2019-09-05
Release date:2020-09-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Diversity of Omega Glutathione Transferases in mushroom-forming fungi revealed by phylogenetic, transcriptomic, biochemical and structural approaches.
Fungal Genet Biol., 148, 2021
6SRA
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BU of 6sra by Molmil
Crystal structure of glutathione transferase Omega 2C from Trametes versicolor in complex with naringenin
Descriptor: GLUTATHIONE, R-naringenin, glutathione transferase
Authors:Schwartz, M, Favier, F, Didierjean, C.
Deposit date:2019-09-05
Release date:2020-09-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:Diversity of Omega Glutathione Transferases in mushroom-forming fungi revealed by phylogenetic, transcriptomic, biochemical and structural approaches.
Fungal Genet Biol., 148, 2021
6W35
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BU of 6w35 by Molmil
A new Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-fluoranyl-~{N}-[(2~{R})-1-[1-(2~{H}-indazol-5-yl)-3-methyl-2,4-bis(oxidanylidene)-1,3,8-triazaspiro[4.5]decan-8-yl]-3-methyl-1-oxidanylidene-butan-2-yl]-5-(trifluoromethyl)benzamide, CALCIUM ION, ...
Authors:Cuozzo, J.W.
Deposit date:2020-03-09
Release date:2020-07-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry.
J.Med.Chem., 63, 2020
4BPB
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BU of 4bpb by Molmil
STRUCTURAL INSIGHTS INTO RNA RECOGNITION BY RIG-I
Descriptor: 5'-R(*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP)-3', PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, SULFATE ION, ...
Authors:Luo, D, Pyle, A.M.
Deposit date:2013-05-23
Release date:2013-06-19
Method:X-RAY DIFFRACTION (2.584 Å)
Cite:Structural Insights Into RNA Recognition by Rig-I.
Cell(Cambridge,Mass.), 147, 2011
5EQE
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BU of 5eqe by Molmil
Crystal structure of choline kinase alpha-1 bound by [4-[(4-methyl-1,4-diazepan-1-yl)methyl]phenyl]methanamine (compound 11)
Descriptor: Choline kinase alpha, [4-[(4-methyl-1,4-diazepan-1-yl)methyl]phenyl]methanamine
Authors:Zhou, T, Zhu, X, Dalgarno, D.C.
Deposit date:2015-11-12
Release date:2016-01-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Novel Small Molecule Inhibitors of Choline Kinase Identified by Fragment-Based Drug Discovery.
J.Med.Chem., 59, 2016
5EQY
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BU of 5eqy by Molmil
Crystal structure of choline kinase alpha-1 bound by 5-[(4-methyl-1,4-diazepan-1-yl)methyl]-2-[4-[(4-methyl-1,4-diazepan-1-yl)methyl]phenyl]benzenecarbonitrile (compound 65)
Descriptor: 5-[(4-methyl-1,4-diazepan-1-yl)methyl]-2-[4-[(4-methyl-1,4-diazepan-1-yl)methyl]phenyl]benzenecarbonitrile, Choline kinase alpha
Authors:Zhou, T, Zhu, X, Dalgarno, D.C.
Deposit date:2015-11-13
Release date:2016-01-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Novel Small Molecule Inhibitors of Choline Kinase Identified by Fragment-Based Drug Discovery.
J.Med.Chem., 59, 2016
5EQP
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BU of 5eqp by Molmil
Crystal structure of choline kinase alpha-1 bound by 6-[(4-methyl-1,4-diazepan-1-yl)methyl]quinoline (compound 37)
Descriptor: 6-[(4-methyl-1,4-diazepan-1-yl)methyl]quinoline, Choline kinase alpha
Authors:Zhou, T, Zhu, X, Dalgarno, D.C.
Deposit date:2015-11-13
Release date:2016-01-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Novel Small Molecule Inhibitors of Choline Kinase Identified by Fragment-Based Drug Discovery.
J.Med.Chem., 59, 2016
5A10
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BU of 5a10 by Molmil
The crystal structure of Ta-TFP, a thiocyanate-forming protein involved in glucosinolate breakdown (space group C2)
Descriptor: ACETATE ION, SODIUM ION, THIOCYANATE FORMING PROTEIN
Authors:Krausze, J, Gumz, F, Wittstock, U.
Deposit date:2015-04-27
Release date:2015-08-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.423 Å)
Cite:The Crystal Structure of the Thiocyanate-Forming Protein from Thlaspi Arvense, a Kelch Protein Involved in Glucosinolate Breakdown.
Plant Mol.Biol., 89, 2015
5A11
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BU of 5a11 by Molmil
The crystal structure of Ta-TFP, a thiocyanate-forming protein involved in glucosinolate breakdown (space group P21)
Descriptor: IODIDE ION, THIOCYANATE FORMING PROTEIN
Authors:Krausze, J, Gumz, F, Wittstock, U.
Deposit date:2015-04-27
Release date:2015-08-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:The Crystal Structure of the Thiocyanate-Forming Protein from Thlaspi Arvense, a Kelch Protein Involved in Glucosinolate Breakdown.
Plant Mol.Biol., 89, 2015
3FWB
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BU of 3fwb by Molmil
Sac3:Sus1:Cdc31 complex
Descriptor: Cell division control protein 31, Nuclear mRNA export protein SAC3, Protein SUS1
Authors:Stewart, M, Jani, D.
Deposit date:2009-01-17
Release date:2009-04-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export.
Mol.Cell, 33, 2009
3FWC
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BU of 3fwc by Molmil
Sac3:Sus1:Cdc31 complex
Descriptor: Cell division control protein 31, Nuclear mRNA export protein SAC3, Protein SUS1, ...
Authors:Stewart, M, Jani, D.
Deposit date:2009-01-17
Release date:2009-04-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export.
Mol.Cell, 33, 2009
3G8Q
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BU of 3g8q by Molmil
A cytidine deaminase edits C-to-U in transfer RNAs in archaea
Descriptor: Predicted RNA-binding protein, contains THUMP domain, SODIUM ION, ...
Authors:Xiong, Y, Stanley, B.J.
Deposit date:2009-02-12
Release date:2009-05-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A cytidine deaminase edits C to U in transfer RNAs in Archaea
Science, 324, 2009
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