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8H5E
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BU of 8h5e by Molmil
Crystal structure of the MgtE TM domain in complex with Ca2+ ions at 2.5 angstrom resolution
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, Magnesium transporter MgtE
Authors:Teng, X, Sheng, D, Hattori, M.
Deposit date:2022-10-13
Release date:2022-12-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ion selectivity mechanism of the MgtE channel for Mg 2+ over Ca 2 .
Iscience, 25, 2022
8H70
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BU of 8h70 by Molmil
Crystal structure of the catalytic ATP-binding domain of the PhoR sensor histidine kinase from Vibrio cholera
Descriptor: DI(HYDROXYETHYL)ETHER, Phosphate regulon sensor protein PhoR
Authors:Jia, R, Zhao, W, Hattori, M.
Deposit date:2022-10-18
Release date:2023-02-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structure of the catalytic ATP-binding domain of the PhoR sensor histidine kinase.
Proteins, 91, 2023
4WIB
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BU of 4wib by Molmil
Crystal structure of Magnesium transporter MgtE
Descriptor: CALCIUM ION, Magnesium transporter MgtE
Authors:Takeda, H, Hattori, M, Nishizawa, T, Yamashita, K, Shah, S.T.A, Caffrey, M, Maturana, A.D, Ishitani, R, Nureki, O.
Deposit date:2014-09-25
Release date:2014-12-03
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg(2+) channel MgtE
Nat Commun, 5, 2014
5H35
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BU of 5h35 by Molmil
Crystal structures of the TRIC trimeric intracellular cation channel orthologue from Sulfolobus solfataricus
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Fab Heavy Chain, Fab Light Chain, ...
Authors:Kasuya, G, Hiraizumi, M, Hattori, M, Nureki, O.
Deposit date:2016-10-20
Release date:2017-01-11
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (2.642 Å)
Cite:Crystal structures of the TRIC trimeric intracellular cation channel orthologues
Cell Res., 26, 2016
5H36
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BU of 5h36 by Molmil
Crystal structures of the TRIC trimeric intracellular cation channel orthologue from Rhodobacter sphaeroides
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Uncharacterized protein TRIC
Authors:Kasuya, G, Hiraizumi, M, Hattori, M, Nureki, O.
Deposit date:2016-10-20
Release date:2017-01-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.409 Å)
Cite:Crystal structures of the TRIC trimeric intracellular cation channel orthologues
Cell Res., 26, 2016
5F1C
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BU of 5f1c by Molmil
Crystal structure of an invertebrate P2X receptor from the Gulf Coast tick in the presence of ATP and Zn2+ ion at 2.9 Angstroms
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Putative uncharacterized protein, ...
Authors:Kasuya, G, Hattori, M, Ishitani, R, Nureki, O.
Deposit date:2015-11-30
Release date:2016-03-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Insights into Divalent Cation Modulations of ATP-Gated P2X Receptor Channels
Cell Rep, 14, 2016
1WAB
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BU of 1wab by Molmil
PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Descriptor: ACETATE ION, PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Authors:Ho, Y.S, Swenson, L, Derewenda, U, Serre, L, Wei, Y, Dauter, Z, Hattori, M, Aoki, J, Arai, H, Adachi, T, Inoue, K, Derewenda, Z.S.
Deposit date:1996-10-30
Release date:1997-11-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer.
Nature, 385, 1997
4U9L
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BU of 4u9l by Molmil
Structure of a membrane protein
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, MAGNESIUM ION, Magnesium transporter MgtE
Authors:Takeda, H, Hattori, M, Nishizawa, T, Yamashita, K, Shah, S.T.A, Caffrey, M, Maturana, A.D, Ishitani, R, Nureki, O.
Deposit date:2014-08-06
Release date:2014-12-03
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg(2+) channel MgtE
Nat Commun, 5, 2014
4U9N
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BU of 4u9n by Molmil
Structure of a membrane protein
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, MANGANESE (II) ION, Magnesium transporter MgtE, ...
Authors:Takeda, H, Hattori, M, Nishizawa, T, Yamashita, K, Shah, S.T.A, Caffrey, M, Maturana, A.D, Ishitani, R, Nureki, O.
Deposit date:2014-08-06
Release date:2014-12-03
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg(2+) channel MgtE
Nat Commun, 5, 2014
8WGE
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BU of 8wge by Molmil
Cryo-EM structure of the ZAC zinc-activated channel in the Cys-loop receptor superfamily
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ZAC
Authors:Jin, F, Hattori, M.
Deposit date:2023-09-21
Release date:2024-09-25
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of the ZAC zinc-activated channel in the Cys-loop receptor superfamily
Proc.Natl.Acad.Sci.USA, 2024
3FOM
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BU of 3fom by Molmil
Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide IQQSIERL
Descriptor: 8 residue synthetic peptide, Beta-2-microglobulin, CHLORIDE ION, ...
Authors:Brims, D.R, Qian, J, Jarchum, I, Yamada, T, Mikesh, L, Palmieri, E, Lund, T, Hattori, M, Shabanowitz, J, Hunt, D.F, Ramagopal, U.A, Malashkevich, V.N, Almo, S.C, Nathenson, S.G, DiLorenzo, T.P.
Deposit date:2008-12-30
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect.
Int.Immunol., 22, 2010
3FON
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BU of 3fon by Molmil
Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide VNDIFEAI
Descriptor: Beta-2-microglobulin, MHC, Peptide
Authors:Malashkevich, V.N, Qian, J, Jarchum, I, Yamada, T, Mikesh, L, Palmieri, E, Lund, T, Hattori, M, Shabanowitz, J, Hunt, D.F, Ramagopal, U.A, Brims, D.R, Almo, S.C, Nathenson, S.G, DiLorenzo, T.P.
Deposit date:2008-12-30
Release date:2010-01-12
Last modified:2020-02-05
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect.
Int.Immunol., 22, 2010
3FOL
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BU of 3fol by Molmil
Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide VNDIFERI
Descriptor: 8 residue synthetic peptide, Beta-2-microglobulin, MHC
Authors:Brims, D.R, Qian, J, Jarchum, I, Yamada, T, Mikesh, L, Palmieri, E, Lund, T, Hattori, M, Shabanowitz, J, Hunt, D.F, Ramagopal, U.A, Malashkevich, V.N, Almo, S.C, Nathenson, S.G, DiLorenzo, T.P.
Deposit date:2008-12-30
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect
Int.Immunol., 22, 2010
7CFG
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BU of 7cfg by Molmil
Structure of the transmembrane domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with Mg2+
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Hemolysin, MAGNESIUM ION, ...
Authors:Huang, Y, Jin, F, Hattori, M.
Deposit date:2020-06-25
Release date:2021-02-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for the Mg 2+ recognition and regulation of the CorC Mg 2+ transporter.
Sci Adv, 7, 2021
7CFI
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BU of 7cfi by Molmil
Structure of the CBS domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Hemolysin, MAGNESIUM ION
Authors:Huang, Y, Jin, F, Hattori, M.
Deposit date:2020-06-25
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural basis for the Mg 2+ recognition and regulation of the CorC Mg 2+ transporter.
Sci Adv, 7, 2021
7CFF
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BU of 7cff by Molmil
Structure of the thermostabilized transmembrane domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with Mg2+
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hemolysin, ...
Authors:Huang, Y, Jin, F, Hattori, M.
Deposit date:2020-06-25
Release date:2021-02-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the Mg 2+ recognition and regulation of the CorC Mg 2+ transporter.
Sci Adv, 7, 2021
7CFH
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BU of 7cfh by Molmil
Structure of the CBS domain of the bacterial CNNM/CorC family Mg2+ transporter
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Hemolysin
Authors:Huang, Y, Jin, F, Hattori, M.
Deposit date:2020-06-25
Release date:2021-02-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the Mg 2+ recognition and regulation of the CorC Mg 2+ transporter.
Sci Adv, 7, 2021
5X9H
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BU of 5x9h by Molmil
Crystal structure of the Mg2+ channel MgtE in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Magnesium transporter MgtE
Authors:Tomita, A, Hattori, M, Nureki, O.
Deposit date:2017-03-07
Release date:2017-08-16
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.598 Å)
Cite:ATP-dependent modulation of MgtE in Mg(2+) homeostasis
Nat Commun, 8, 2017
5X9G
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BU of 5x9g by Molmil
Crystal structure of the cytosolic domain of the Mg2+ channel MgtE in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Magnesium transporter MgtE
Authors:Tomita, A, Hattori, M, Nureki, O.
Deposit date:2017-03-07
Release date:2017-08-16
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:ATP-dependent modulation of MgtE in Mg(2+) homeostasis
Nat Commun, 8, 2017
5XW6
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BU of 5xw6 by Molmil
Crystal structure of the chicken ATP-gated P2X7 receptor channel in the presence of competitive antagonist TNP-ATP at 3.1 Angstroms
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, P2X purinoceptor, SPIRO(2,4,6-TRINITROBENZENE[1,2A]-2O',3O'-METHYLENE-ADENINE-TRIPHOSPHATE
Authors:Kasuya, G, Hattori, M, Nureki, O.
Deposit date:2017-06-29
Release date:2017-10-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural insights into the competitive inhibition of the ATP-gated P2X receptor channel
Nat Commun, 8, 2017
7CFK
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BU of 7cfk by Molmil
Structure of the CBS domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with the novel inhibitor IGN95a
Descriptor: (2S)-2-[(6-azanyl-9H-purin-8-yl)sulfanyl]butanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Hemolysin
Authors:Huang, Y, Jin, F, Hattori, M.
Deposit date:2020-06-25
Release date:2021-04-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Identification and mechanistic analysis of an inhibitor of the CorC Mg 2+ transporter.
Iscience, 24, 2021
5YVE
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BU of 5yve by Molmil
Crystal structure of human P2X3 receptor in complex with the AF-219 negative allosteric modulator
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[2,4-bis(azanyl)pyrimidin-5-yl]oxy-2-methoxy-4-propan-2-yl-benzenesulfonamide, MAGNESIUM ION, ...
Authors:Wang, Y, Hattori, M.
Deposit date:2017-11-25
Release date:2018-04-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Druggable negative allosteric site of P2X3 receptors.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5WZY
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BU of 5wzy by Molmil
Crystal structure of the P2X4 receptor from zebrafish in the presence of CTP at 2.8 Angstroms
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYTIDINE-5'-TRIPHOSPHATE, GLYCEROL, ...
Authors:Kasuya, G, Hattori, M, Nureki, O.
Deposit date:2017-01-19
Release date:2017-04-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:Structural insights into the nucleotide base specificity of P2X receptors
Sci Rep, 7, 2017
2ZZT
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BU of 2zzt by Molmil
Crystal structure of the cytosolic domain of the cation diffusion facilitator family protein
Descriptor: Putative uncharacterized protein, SULFATE ION
Authors:Higuchi, T, Hattori, M, Tanaka, Y, Ishitani, R, Nureki, O.
Deposit date:2009-02-25
Release date:2009-08-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.842 Å)
Cite:Crystal structure of the cytosolic domain of the cation diffusion facilitator family protein
Proteins, 76, 2009
4IKX
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BU of 4ikx by Molmil
Crystal structure of peptide transporter POT (E310Q mutant)
Descriptor: Di-tripeptide ABC transporter (Permease), OLEIC ACID, SULFATE ION
Authors:Doki, S, Kato, H.E, Ishitani, R, Nureki, O.
Deposit date:2012-12-28
Release date:2013-07-10
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT.
Proc.Natl.Acad.Sci.USA, 110, 2013

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