4Z2T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4z2t by Molmil](/molmil-images/mine/4z2t) | |
3NQ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nq1 by Molmil](/molmil-images/mine/3nq1) | Crystal Structure of Tyrosinase from Bacillus megaterium in complex with inhibitor kojic acid | Descriptor: | 5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE, COPPER (II) ION, Tyrosinase, ... | Authors: | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2010-06-29 | Release date: | 2010-11-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | First structures of an active bacterial tyrosinase reveal copper plasticity. J.Mol.Biol., 405, 2011
|
|
3NQ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nq5 by Molmil](/molmil-images/mine/3nq5) | Crystal Structure of Tyrosinase from Bacillus megaterium R209H mutant | Descriptor: | COPPER (II) ION, Tyrosinase, ZINC ION | Authors: | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2010-06-29 | Release date: | 2010-11-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | First structures of an active bacterial tyrosinase reveal copper plasticity. J.Mol.Biol., 405, 2011
|
|
3NQ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nq0 by Molmil](/molmil-images/mine/3nq0) | Crystal Structure of Tyrosinase from Bacillus megaterium crystallized in the absence of Zinc | Descriptor: | COPPER (II) ION, Tyrosinase | Authors: | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2010-06-29 | Release date: | 2010-11-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | First structures of an active bacterial tyrosinase reveal copper plasticity. J.Mol.Biol., 405, 2011
|
|
3NPY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3npy by Molmil](/molmil-images/mine/3npy) | Crystal Structure of Tyrosinase from Bacillus megaterium soaked in CuSO4 | Descriptor: | CHLORIDE ION, COPPER (II) ION, Tyrosinase, ... | Authors: | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2010-06-29 | Release date: | 2010-11-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.192 Å) | Cite: | First structures of an active bacterial tyrosinase reveal copper plasticity. J.Mol.Biol., 405, 2011
|
|
3NTM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ntm by Molmil](/molmil-images/mine/3ntm) | Crystal Structure of Tyrosinase from Bacillus megaterium crystallized in the absence of zinc, partial occupancy of CuB | Descriptor: | COPPER (II) ION, Tyrosinase | Authors: | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2010-07-05 | Release date: | 2010-11-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | First structures of an active bacterial tyrosinase reveal copper plasticity J.Mol.Biol., 405, 2011
|
|
3NM8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nm8 by Molmil](/molmil-images/mine/3nm8) | Crystal structure of Tyrosinase from Bacillus megaterium | Descriptor: | CHLORIDE ION, COPPER (II) ION, Tyrosinase, ... | Authors: | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2010-06-22 | Release date: | 2010-11-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | First structures of an active bacterial tyrosinase reveal copper plasticity J.Mol.Biol., 405, 2011
|
|
6S3J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s3j by Molmil](/molmil-images/mine/6s3j) | Crystal Structure of lipase from Geobacillus stearothermophilus T6 variant E134C/F149C | Descriptor: | CALCIUM ION, Lipase, ZINC ION | Authors: | Gihaz, S, Bash, Y, Rush, I, Shahar, A, Pazy, Y, Fishman, A. | Deposit date: | 2019-06-25 | Release date: | 2019-10-09 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Bridges to Stability: Engineering Disulfide Bonds Towards Enhanced Lipase Biodiesel Synthesis Chemcatchem, 2019
|
|
6S3V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s3v by Molmil](/molmil-images/mine/6s3v) | Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant E251C/G332C | Descriptor: | CALCIUM ION, Lipase, ZINC ION | Authors: | Gihaz, S, Bash, Y, Rush, I, Shahar, A, Pazy, Y, Fishman, A. | Deposit date: | 2019-06-26 | Release date: | 2019-10-09 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Bridges to Stability: Engineering Disulfide Bonds Towards Enhanced Lipase Biodiesel Synthesis Chemcatchem, 2019
|
|
6S3G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s3g by Molmil](/molmil-images/mine/6s3g) | Crystal Structure of lipase from Geobacillus stearothermophilus T6 variant A187C/F291C | Descriptor: | CALCIUM ION, Lipase, ZINC ION | Authors: | Gihaz, S, Bash, Y, Rush, I, Shahar, A, Pazy, Y, Fishman, A. | Deposit date: | 2019-06-25 | Release date: | 2019-10-09 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Bridges to Stability: Engineering Disulfide Bonds Towards Enhanced Lipase Biodiesel Synthesis Chemcatchem, 2019
|
|
4J6V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4j6v by Molmil](/molmil-images/mine/4j6v) | Crystal Structure of Tyrosinase from Bacillus megaterium N205D mutant | Descriptor: | COPPER (II) ION, Tyrosinase | Authors: | Kanteev, M, Goldfeder, M, Adir, N, Fishman, A. | Deposit date: | 2013-02-12 | Release date: | 2013-12-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The mechanism of copper uptake by tyrosinase from Bacillus megaterium. J.Biol.Inorg.Chem., 18, 2013
|
|
4HD4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hd4 by Molmil](/molmil-images/mine/4hd4) | Crystal Structure of Tyrosinase from Bacillus megaterium V218F mutant | Descriptor: | COPPER (II) ION, Tyrosinase | Authors: | Goldfeder, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2012-10-02 | Release date: | 2013-01-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Influencing the monophenolase/diphenolase activity ratio in tyrosinase. Biochim.Biophys.Acta, 1834, 2013
|
|
4HD7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hd7 by Molmil](/molmil-images/mine/4hd7) | Crystal Structure of Tyrosinase from Bacillus megaterium V218G mutant soaked in CuSO4 | Descriptor: | COPPER (II) ION, Tyrosinase | Authors: | Goldfeder, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2012-10-02 | Release date: | 2013-01-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Influencing the monophenolase/diphenolase activity ratio in tyrosinase. Biochim.Biophys.Acta, 1834, 2013
|
|
4J6T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4j6t by Molmil](/molmil-images/mine/4j6t) | Crystal Structure of Tyrosinase from Bacillus megaterium F197A mutant | Descriptor: | COPPER (II) ION, Tyrosinase | Authors: | Kanteev, M, Goldfeder, M, Adir, N, Fishman, A. | Deposit date: | 2013-02-12 | Release date: | 2013-12-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | The mechanism of copper uptake by tyrosinase from Bacillus megaterium. J.Biol.Inorg.Chem., 18, 2013
|
|
4J6U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4j6u by Molmil](/molmil-images/mine/4j6u) | |
4HD6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hd6 by Molmil](/molmil-images/mine/4hd6) | Crystal Structure of Tyrosinase from Bacillus megaterium V218F mutant soaked in CuSO4 | Descriptor: | COPPER (II) ION, Tyrosinase | Authors: | Goldfeder, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2012-10-02 | Release date: | 2013-01-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Influencing the monophenolase/diphenolase activity ratio in tyrosinase. Biochim.Biophys.Acta, 1834, 2013
|
|
6EM0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6em0 by Molmil](/molmil-images/mine/6em0) | Crystal Structure of 2-hydroxybiphenyl 3-monooxygenase M321A from Pseudomonas azelaica | Descriptor: | 2-hydroxybiphenyl-3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Deri, B, Bregman-Cohen, A, Pazy Benhar, Y, Fishman, A. | Deposit date: | 2017-10-01 | Release date: | 2018-01-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Altering 2-Hydroxybiphenyl 3-Monooxygenase Regioselectivity by Protein Engineering for the Production of a New Antioxidant. Chembiochem, 19, 2018
|
|
6EI4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ei4 by Molmil](/molmil-images/mine/6ei4) | Crystal Structure of tyrosinase from Bacillus megaterium with B5N inhibitor in the active site | Descriptor: | COPPER (II) ION, Tyrosinase, [4-[(4-fluorophenyl)methyl]piperazin-1-yl]-(2-methylphenyl)methanone | Authors: | Deri, B, Gitto, R, Pazy Benhar, Y, Fishman, A. | Deposit date: | 2017-09-17 | Release date: | 2018-04-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments. J. Med. Chem., 61, 2018
|
|
4P6S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4p6s by Molmil](/molmil-images/mine/4p6s) | Crystal Structure of tyrosinase from Bacillus megaterium with L-DOPA in the active site | Descriptor: | 3,4-DIHYDROXYPHENYLALANINE, Tyrosinase, ZINC ION | Authors: | Goldfeder, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2014-03-25 | Release date: | 2014-07-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Determination of tyrosinase substrate-binding modes reveals mechanistic differences between type-3 copper proteins. Nat Commun, 5, 2014
|
|
4P6R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4p6r by Molmil](/molmil-images/mine/4p6r) | Crystal Structure of tyrosinase from Bacillus megaterium with tyrosine in the active site | Descriptor: | TYROSINE, Tyrosinase, ZINC ION | Authors: | Goldfeder, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2014-03-25 | Release date: | 2014-07-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Determination of tyrosinase substrate-binding modes reveals mechanistic differences between type-3 copper proteins. Nat Commun, 5, 2014
|
|
5OAE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5oae by Molmil](/molmil-images/mine/5oae) | Crystal Structure of tyrosinase from Bacillus megaterium with SVF inhibitor in the active site | Descriptor: | 1-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]ethanone, COPPER (II) ION, Tyrosinase | Authors: | Deri, B, Gitto, R, Pazy Benhar, Y, Fishman, A. | Deposit date: | 2017-06-21 | Release date: | 2018-04-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments. J. Med. Chem., 61, 2018
|
|
4D87
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4d87 by Molmil](/molmil-images/mine/4d87) | |
6FZC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fzc by Molmil](/molmil-images/mine/6fzc) | Crystal Structure of lipase from Geobacillus stearothermophilus T6 variant L184F/L360F | Descriptor: | CALCIUM ION, Lipase, ZINC ION | Authors: | Gihaz, S, Kanteev, M, Pazy, Y, Fishman, A. | Deposit date: | 2018-03-14 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Filling the Void: Introducing Aromatic Interactions into Solvent Tunnels To Enhance Lipase Stability in Methanol. Appl.Environ.Microbiol., 84, 2018
|
|
6FZA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fza by Molmil](/molmil-images/mine/6fza) | Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant A187F | Descriptor: | CALCIUM ION, Lipase, ZINC ION | Authors: | Gihaz, S, Kanteev, M, Pazy, Y, Fishman, A. | Deposit date: | 2018-03-14 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Filling the Void: Introducing Aromatic Interactions into Solvent Tunnels To Enhance Lipase Stability in Methanol. Appl.Environ.Microbiol., 84, 2018
|
|
6FZ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fz8 by Molmil](/molmil-images/mine/6fz8) | Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant L184F/A187F | Descriptor: | CALCIUM ION, Lipase, ZINC ION | Authors: | Gihaz, S, Kanteev, M, Pazy, Y, Fishman, A. | Deposit date: | 2018-03-14 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Filling the Void: Introducing Aromatic Interactions into Solvent Tunnels To Enhance Lipase Stability in Methanol. Appl.Environ.Microbiol., 84, 2018
|
|