7UU5
| Crystal structure of APOBEC3G complex with 5'-Overhang dsRNA | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, RNA (5'-R(P*UP*AP*AP*CP*CP*GP*CP*AP*GP*CP*G)-3'), RNA (5'-R(P*UP*AP*AP*CP*GP*CP*UP*GP*CP*GP*G)-3'), ... | Authors: | Yang, H, Li, S, Chen, X.S. | Deposit date: | 2022-04-28 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G. Nat Commun, 13, 2022
|
|
7UU4
| Crystal structure of APOBEC3G complex with ssRNA | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, RNA (5'-R(P*UP*AP*AP*UP*UP*U)-3'), SULFATE ION, ... | Authors: | Yang, H, Li, S, Chen, X.S. | Deposit date: | 2022-04-28 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G. Nat Commun, 13, 2022
|
|
7UU3
| Crystal structure of APOBEC3G complex with 3'overhangs RNA-Complex | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, RNA (5'-R(*CP*CP*CP*AP*CP*GP*GP*GP*AP*AP*U)-3'), RNA (5'-R(*CP*CP*CP*GP*UP*GP*GP*GP*AP*AP*U)-3'), ... | Authors: | Yang, H, Li, S, Chen, X.S. | Deposit date: | 2022-04-28 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.099 Å) | Cite: | Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G. Nat Commun, 13, 2022
|
|
8UD2
| |
8UD3
| SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, consensus form | Descriptor: | Non-structural protein 15, RNA (35-MER) | Authors: | Ito, F, Yang, H, Zhou, Z.H, Chen, X.S. | Deposit date: | 2023-09-28 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.67 Å) | Cite: | Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15. Protein Cell, 2024
|
|
8UD4
| SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, state 1 | Descriptor: | Non-structural protein 15, RNA (35-MER) | Authors: | Ito, F, Yang, H, Zhou, Z.H, Chen, X.S. | Deposit date: | 2023-09-28 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15. Protein Cell, 2024
|
|
8UD5
| SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, state 2 | Descriptor: | Non-structural protein 15, RNA (35-MER) | Authors: | Ito, F, Yang, H, Zhou, Z.H, Chen, X.S. | Deposit date: | 2023-09-28 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15. Protein Cell, 2024
|
|
8FVJ
| Dimeric form of HIV-1 Vif in complex with human CBF-beta, ELOB, ELOC, and CUL5 | Descriptor: | Core-binding factor subunit beta, Cullin-5, Elongin-B, ... | Authors: | Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S. | Deposit date: | 2023-01-19 | Release date: | 2023-09-06 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H. Nat Commun, 14, 2023
|
|
8FY6
| |
8FY7
| SARS-CoV-2 main protease in complex with covalent inhibitor | Descriptor: | 3C-like proteinase nsp5, 4-methoxy-N-[(2S)-4-methyl-1-oxo-1-({(2S)-1-[(3S)-2-oxopyrrolidin-3-yl]but-3-en-2-yl}amino)pentan-2-yl]-1H-indole-2-carboxamide | Authors: | Fried, W, Chen, X.S. | Deposit date: | 2023-01-25 | Release date: | 2023-08-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Alkyne as a Latent Warhead to Covalently Target SARS-CoV-2 Main Protease. J.Med.Chem., 66, 2023
|
|
8FVI
| Human APOBEC3H bound to HIV-1 Vif in complex with CBF-beta, ELOB, ELOC, and CUL5 | Descriptor: | Core-binding factor subunit beta, Cullin 5, DNA dC->dU-editing enzyme APOBEC-3H, ... | Authors: | Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S. | Deposit date: | 2023-01-19 | Release date: | 2023-09-06 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H. Nat Commun, 14, 2023
|
|
8E40
| Full-length APOBEC3G in complex with HIV-1 Vif, CBF-beta, and fork RNA | Descriptor: | Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, RNA, ... | Authors: | Ito, F, Alvarez-Cabrera, A.L, Liu, S, Yang, H, Shiriaeva, A, Zhou, Z.H, Chen, X.S. | Deposit date: | 2022-08-17 | Release date: | 2023-01-11 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Structural basis for HIV-1 antagonism of host APOBEC3G via Cullin E3 ligase. Sci Adv, 9, 2023
|
|
8EDJ
| Crystal structure of rA3G-ssRNA-GA | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, RNA (5'-R(P*UP*GP*AP*UP*UP*U)-3'), SULFATE ION, ... | Authors: | Pacheco, J, Yang, H.J, Li, S.-X, Chen, X.S. | Deposit date: | 2022-09-04 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G. Nat Commun, 13, 2022
|
|
4E2I
| The Complex Structure of the SV40 Helicase Large T Antigen and p68 Subunit of DNA Polymerase Alpha-Primase | Descriptor: | DNA polymerase alpha subunit B, Large T antigen, ZINC ION | Authors: | Zhou, B, Arnett, D.R, Yu, X, Brewster, A, Sowd, G.A, Xie, C.L, Vila, S, Gai, D, Fanning, E, Chen, X.S. | Deposit date: | 2012-03-08 | Release date: | 2012-06-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (5 Å) | Cite: | Structural basis for the interaction of a hexameric replicative helicase with the regulatory subunit of human DNA polymerase alpha-primase. J.Biol.Chem., 287, 2012
|
|
3BGW
| The Structure Of A DnaB-Like Replicative Helicase And Its Interactions With Primase | Descriptor: | DNAB-Like Replicative Helicase | Authors: | Wang, G, Klein, M.G, Tokonzaba, E, Zhang, Y, Holden, L.G, Chen, X.S. | Deposit date: | 2007-11-27 | Release date: | 2007-12-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.91 Å) | Cite: | The structure of a DnaB-family replicative helicase and its interactions with primase. Nat.Struct.Mol.Biol., 15, 2008
|
|
2H1L
| |
3BH0
| ATPase Domain of G40P | Descriptor: | DNAB-LIKE REPLICATIVE HELICASE | Authors: | Wang, G, Klein, M.G, Tokonzaba, E, Zhang, Y, Holden, L.G, Chen, X.S. | Deposit date: | 2007-11-27 | Release date: | 2007-12-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The structure of a DnaB-family replicative helicase and its interactions with primase. Nat.Struct.Mol.Biol., 15, 2008
|
|
2Q9Q
| The crystal structure of full length human GINS complex | Descriptor: | DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, GINS complex subunit 3, ... | Authors: | Chang, Y.P, Wang, G, Chen, X.S. | Deposit date: | 2007-06-13 | Release date: | 2007-08-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Crystal structure of the GINS complex and functional insights into its role in DNA replication. Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
5W1O
| Crystal Structure of HPV16 L1 Pentamer Bound to Heparin Oligosaccharides | Descriptor: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose, 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose, Major capsid protein L1 | Authors: | Dasgupta, J, Chen, X.S. | Deposit date: | 2017-06-04 | Release date: | 2017-10-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of oligosaccharide receptor recognition by human papillomavirus. J. Biol. Chem., 286, 2011
|
|
5W2M
| APOBEC3F Catalytic Domain Complex with a Single-Stranded DNA | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA dC->dU-editing enzyme APOBEC-3F, ZINC ION | Authors: | Fang, Y, Xiao, X, Li, S.-X, Wolfe, A, Chen, X.S. | Deposit date: | 2017-06-06 | Release date: | 2017-12-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Molecular Interactions of a DNA Modifying Enzyme APOBEC3F Catalytic Domain with a Single-Stranded DNA. J. Mol. Biol., 430, 2018
|
|
5W45
| Crystal structure of APOBEC3H | Descriptor: | APOBEC3H, ZINC ION | Authors: | Ito, F, Yang, H.J, Xiao, X, Li, S.X, Wolfe, A, Zirkle, B, Arutiunian, V, Chen, X.S. | Deposit date: | 2017-06-09 | Release date: | 2018-03-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.486 Å) | Cite: | Understanding the Structure, Multimerization, Subcellular Localization and mC Selectivity of a Genomic Mutator and Anti-HIV Factor APOBEC3H. Sci Rep, 8, 2018
|
|
5TKM
| Crystal structure of human APOBEC3B N-terminal Domain | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3B, ZINC ION | Authors: | Xiao, X, Yang, H, Arutiunian, V, Besse, G, Morimoto, C, Zirkle, B, Chen, X.S. | Deposit date: | 2016-10-07 | Release date: | 2017-06-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation. Nucleic Acids Res., 45, 2017
|
|
4ME3
| 1.8 Angstrom Crystal Structure of the N-terminal Domain of an Archaeal MCM | Descriptor: | DNA replication licensing factor MCM related protein, ZINC ION | Authors: | Fu, Y, Slaymaker, I.M, Wang, G, Chen, X.S. | Deposit date: | 2013-08-24 | Release date: | 2014-01-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.794 Å) | Cite: | The 1.8- angstrom Crystal Structure of the N-Terminal Domain of an Archaeal MCM as a Right-Handed Filament. J.Mol.Biol., 426, 2014
|
|
4GDF
| A Crystal Structure of SV40 Large T Antigen | Descriptor: | DNA (32-MER), Large T antigen, ZINC ION | Authors: | Chang, Y.P, Xu, M, Chen, X.S. | Deposit date: | 2012-07-31 | Release date: | 2013-04-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mechanism of Origin DNA Recognition and Assembly of an Initiator-Helicase Complex by SV40 Large Tumor Antigen. Cell Rep, 3, 2013
|
|
4FDG
| Crystal Structure of an Archaeal MCM Filament | Descriptor: | Minichromosome maintenance protein MCM, ZINC ION | Authors: | Slaymaker, I.M, Fu, Y, Brewster, A.B, Chen, X.S. | Deposit date: | 2012-05-28 | Release date: | 2013-03-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology. Nucleic Acids Res., 41, 2013
|
|