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7LA6
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BU of 7la6 by Molmil
THE STRUCTURE OF A SENSOR DOMAIN OF A HISTIDINE KINASE (VxrA) FROM VIBRIO CHOLERAE O1 BIOVAR ELTOR STR. N16961, N239 deletion mutant
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, SULFATE ION, ...
Authors:Tan, K, Wu, R, Jedrzejczak, R, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-01-05
Release date:2021-01-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Sensor Domain of Histidine Kinase VxrA of Vibrio cholerae - A Hairpin-swapped Dimer and its Conformational Change.
J.Bacteriol., 203, 2021
8DLB
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BU of 8dlb by Molmil
Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound Z2799209083
Descriptor: 1-[(5S)-5-(3,4-dimethoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one, 3C-like proteinase
Authors:Kovalevsky, A.Y, Coates, L, Kneller, D.W.
Deposit date:2022-07-07
Release date:2023-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2.
J.Chem.Inf.Model., 63, 2023
8DMD
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BU of 8dmd by Molmil
Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound ZZ4461624291
Descriptor: 1-[(3R)-4-[(3-chlorophenyl)methyl]-3-(2-methylpropyl)piperazin-1-yl]ethan-1-one, 3C-like proteinase
Authors:Kovalevsky, A, Coates, L, Kneller, D.W.
Deposit date:2022-07-08
Release date:2023-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2.
J.Chem.Inf.Model., 63, 2023
8DL9
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BU of 8dl9 by Molmil
Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound Z199538122
Descriptor: 1-{4-[(naphthalen-1-yl)methyl]piperazin-1-yl}ethan-1-one, 3C-like proteinase
Authors:Kovalevsky, A.Y, Coates, L, Kneller, D.W.
Deposit date:2022-07-07
Release date:2023-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2.
J.Chem.Inf.Model., 63, 2023
7MWH
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BU of 7mwh by Molmil
Crystal structure of BAZ2A with DNA
Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, DNA (5'-D(*CP*GP*GP*AP*AP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*TP*TP*CP*CP*G)-3'), ...
Authors:Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2021-05-17
Release date:2022-08-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of the BAZ2B TAM domain.
Heliyon, 8, 2022
4QIL
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BU of 4qil by Molmil
Crystal structure of the ROQ domain of human Roquin in complex with the Hmg19 stem-loop RNA
Descriptor: 5'-R(*CP*UP*CP*CP*CP*UP*UP*CP*UP*GP*UP*GP*AP*AP*GP*GP*GP*GP*A)-3', CALCIUM ION, Roquin-1
Authors:Tan, D, Tong, L.
Deposit date:2014-05-31
Release date:2014-07-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The ROQ domain of Roquin recognizes mRNA constitutive-decay element and double-stranded RNA.
Nat.Struct.Mol.Biol., 21, 2014
4QIK
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BU of 4qik by Molmil
Crystal structure of the ROQ domain of human Roquin in complex with the TNF23 RNA duplex
Descriptor: 5'-R(*AP*C*AP*UP*GP*UP*UP*UP*UP*CP*UP*GP*UP*GP*AP*AP*AP*AP*CP*GP*GP*AP*G)-3', CHLORIDE ION, GLYCEROL, ...
Authors:Tan, D, Tong, L.
Deposit date:2014-05-31
Release date:2014-07-16
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The ROQ domain of Roquin recognizes mRNA constitutive-decay element and double-stranded RNA.
Nat.Struct.Mol.Biol., 21, 2014
7WP6
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BU of 7wp6 by Molmil
Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK in complex with three neutralizing antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 36H6 heavy chain, ...
Authors:Zheng, Q, Sun, H, Yuan, Q, Li, S, Xia, N.
Deposit date:2022-01-23
Release date:2023-03-01
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine.
Cell Host Microbe, 30, 2022
7WP8
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BU of 7wp8 by Molmil
Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK1628x in complex with three neutralizing antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 heavy chain, ...
Authors:Zheng, Q, Sun, H, Yuan, Q, Li, S, Xia, N.
Deposit date:2022-01-23
Release date:2023-03-08
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.88 Å)
Cite:Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine.
Cell Host Microbe, 30, 2022
2KFT
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BU of 2kft by Molmil
NMR Solution structure of the first PHD finger domain of human Autoimmune Regulator (AIRE) in complex with Histone H3(1-20Cys) Peptide
Descriptor: Autoimmune regulator, Histone H3, ZINC ION
Authors:Chakravarty, S, Zeng, L, Zhou, M.
Deposit date:2009-02-27
Release date:2009-04-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and Site-Specific Recognition of Histone H3 by the PHD Finger of Human Autoimmune Regulator.
Structure, 17, 2009
2KWJ
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BU of 2kwj by Molmil
Solution structures of the double PHD fingers of human transcriptional protein DPF3 bound to a histone peptide containing acetylation at lysine 14
Descriptor: Histone peptide, ZINC ION, Zinc finger protein DPF3
Authors:Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M.
Deposit date:2010-04-12
Release date:2010-07-14
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b.
Nature, 466, 2010
2KVM
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BU of 2kvm by Molmil
Solution structure of the CBX7 chromodomain in complex with a H3K27me2 peptide
Descriptor: Chromobox protein homolog 7, histone H3 peptide (residues 15-30) with dimethylated lysine 27
Authors:Yap, K.L, Zeng, L, Zhou, M.
Deposit date:2010-03-17
Release date:2010-06-30
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a.
Mol.Cell, 38, 2010
2KWO
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BU of 2kwo by Molmil
Solution structure of the double PHD (plant homeodomain) fingers of human transcriptional protein DPF3b bound to a histone H4 peptide containing N-terminal acetylation at Serine 1
Descriptor: Histone peptide, ZINC ION, Zinc finger protein DPF3
Authors:Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M.
Deposit date:2010-04-14
Release date:2010-07-14
Last modified:2013-06-19
Method:SOLUTION NMR
Cite:Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b.
Nature, 466, 2010
2KWN
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BU of 2kwn by Molmil
Solution structure of the double PHD (plant homeodomain) fingers of human transcriptional protein DPF3b bound to a histone H4 peptide containing acetylation at Lysine 16
Descriptor: Histone peptide, ZINC ION, Zinc finger protein DPF3
Authors:Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M.
Deposit date:2010-04-13
Release date:2010-07-14
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b.
Nature, 466, 2010
2KWK
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BU of 2kwk by Molmil
Solution structures of the double PHD fingers of human transcriptional protein DPF3b bound to a H3 peptide wild type
Descriptor: Histone peptide, ZINC ION, Zinc finger protein DPF3
Authors:Zeng, L, Zhang, Q, Li, S, Plotnikov, A.N, Walsh, M.J, Zhou, M.
Deposit date:2010-04-12
Release date:2010-07-14
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b.
Nature, 466, 2010
2L5D
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BU of 2l5d by Molmil
Solution Structures of human PIWI-like 1 PAZ domain with ssRNA (5'-pUGACA)
Descriptor: 5'-R(*UP*GP*AP*CP*A)-3', Piwi-like protein 1
Authors:Zeng, L, Zhang, Q, Yan, K, Zhou, M.
Deposit date:2010-10-29
Release date:2011-04-20
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural insights into piRNA recognition by the human PIWI-like 1 PAZ domain.
Proteins, 79, 2011
2L5C
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BU of 2l5c by Molmil
Solution structures of human PIWI-like 1 PAZ domain
Descriptor: Piwi-like protein 1
Authors:Zeng, L, Zhang, Q, Yan, K, Zhou, M.
Deposit date:2010-10-29
Release date:2011-04-20
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural insights into piRNA recognition by the human PIWI-like 1 PAZ domain.
Proteins, 79, 2011
2NDF
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BU of 2ndf by Molmil
Solution NMR structures of AF9 yeats domain in complex with histon H3 acetylation at K18
Descriptor: Histone H3 peptide, Protein AF-9
Authors:Zeng, L, Zhou, M.
Deposit date:2016-05-19
Release date:2016-09-07
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain.
Structure, 24, 2016
2NDG
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BU of 2ndg by Molmil
Solution NMR structures of AF9 yeats domain in complex with histone H3 crotonylation at K18
Descriptor: Histone H3 peptide, Protein AF-9
Authors:Zeng, L, Zhou, M.
Deposit date:2016-05-19
Release date:2016-09-07
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain.
Structure, 24, 2016
2ND0
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BU of 2nd0 by Molmil
Solution NMR structures of BRD4 ET domain with LANA peptide
Descriptor: Bromodomain-containing protein 4, LANA
Authors:Zeng, L, Zhou, M.
Deposit date:2016-04-18
Release date:2016-06-29
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Mechanism of Transcriptional Regulator NSD3 Recognition by the ET Domain of BRD4.
Structure, 24, 2016
2NCZ
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BU of 2ncz by Molmil
Solution NMR structures of BRD4 ET domain in complex with NSD3_1 peptide
Descriptor: Bromodomain-containing protein 4, Histone-lysine N-methyltransferase NSD3
Authors:Zeng, L, Zhou, M.
Deposit date:2016-04-18
Release date:2016-06-29
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Mechanism of Transcriptional Regulator NSD3 Recognition by the ET Domain of BRD4.
Structure, 24, 2016
2ND1
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BU of 2nd1 by Molmil
Solution NMR structures of BRD4 ET domain in complex with NSD3_3 peptide
Descriptor: Bromodomain-containing protein 4, Histone-lysine N-methyltransferase NSD3
Authors:Zeng, L, Zhou, M.
Deposit date:2016-04-19
Release date:2016-06-29
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Mechanism of Transcriptional Regulator NSD3 Recognition by the ET Domain of BRD4.
Structure, 24, 2016
1YB4
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BU of 1yb4 by Molmil
Crystal Structure of the Tartronic Semialdehyde Reductase from Salmonella typhimurium LT2
Descriptor: tartronic semialdehyde reductase
Authors:Kim, Y, Wu, R, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2004-12-20
Release date:2005-02-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray crystal structure of GarR-tartronate semialdehyde reductase from Salmonella typhimurium.
J Struct Funct Genomics, 10, 2009
1YQH
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BU of 1yqh by Molmil
Structure of domain of unknown function DUF77 from Bacillus cereus
Descriptor: IG hypothetical 16092
Authors:Midwest Center for Structural Genomics (MCSG)
Deposit date:2005-02-01
Release date:2005-03-15
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of domain of unknown function DUF77 from Bacillus cereus
To be Published
7X7U
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BU of 7x7u by Molmil
Cryo-EM structure of SARS-CoV-2 Delta variant spike protein in complex with three nAbs X01, X10 and X17
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, X01 heavy chain, ...
Authors:Sun, H, Liu, L, Zhang, T, Zheng, Q, Li, S, Xia, N.
Deposit date:2022-03-10
Release date:2022-08-17
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 119, 2022

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