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1ZSO
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BU of 1zso by Molmil
Hypothetical protein from plasmodium falciparum
Descriptor: hypothetical protein
Authors:Holmes, M.A, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-05-24
Release date:2005-06-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum.
Acta Crystallogr.,Sect.F, 62, 2006
2A0M
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BU of 2a0m by Molmil
Arginase superfamily protein from Trypanosoma cruzi
Descriptor: ARGINASE SUPERFAMILY PROTEIN, CHLORIDE ION
Authors:Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-06-16
Release date:2005-07-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Structural genomics of pathogenic protozoa: an overview.
Methods Mol.Biol., 426, 2008
2QVN
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BU of 2qvn by Molmil
Crystal structure of adenosine deaminase from Plasmodium vivax in complex with guanosine
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Adenosine deaminase, GUANOSINE
Authors:Larson, E.T, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2007-08-08
Release date:2007-09-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity.
J.Mol.Biol., 381, 2008
2PGF
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BU of 2pgf by Molmil
Crystal structure of adenosine deaminase from Plasmodium vivax in complex with adenosine
Descriptor: ACETONITRILE, ADENOSINE, ZINC ION, ...
Authors:Larson, E.T, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2007-04-09
Release date:2007-04-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity.
J.Mol.Biol., 381, 2008
2PGR
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BU of 2pgr by Molmil
Crystal structure of adenosine deaminase from Plasmodium vivax in complex with pentostatin
Descriptor: 2'-DEOXYCOFORMYCIN, ACETONITRILE, ZINC ION, ...
Authors:Larson, E.T, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2007-04-10
Release date:2007-04-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity.
J.Mol.Biol., 381, 2008
1MDA
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BU of 1mda by Molmil
CRYSTAL STRUCTURE OF AN ELECTRON-TRANSFER COMPLEX BETWEEN METHYLAMINE DEHYDROGENASE AND AMICYANIN
Descriptor: AMICYANIN, COPPER (II) ION, METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT), ...
Authors:Chen, L, Durley, R, Mathews, F.S.
Deposit date:1992-03-02
Release date:1993-10-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of an electron-transfer complex between methylamine dehydrogenase and amicyanin.
Biochemistry, 31, 1992
1YZV
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BU of 1yzv by Molmil
HYPOTHETICAL PROTEIN FROM TRYPANOSOMA CRUZI
Descriptor: HYPOTHETICAL PROTEIN, SULFATE ION
Authors:Caruthers, J, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-02-28
Release date:2005-03-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Crystal structures and proposed structural/functional classification of three protozoan proteins from the isochorismatase superfamily.
Protein Sci., 14, 2005
3P2P
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BU of 3p2p by Molmil
ENHANCED ACTIVITY AND ALTERED SPECIFICITY OF PHOSPHOLIPASE A2 BY DELETION OF A SURFACE LOOP
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Dijkstra, B.W, Thunnissen, M.M.G.M, Kalk, K.H, Drenth, J.
Deposit date:1989-11-29
Release date:1990-01-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Enhanced activity and altered specificity of phospholipase A2 by deletion of a surface loop.
Science, 244, 1989
1SKZ
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BU of 1skz by Molmil
PROTEASE INHIBITOR
Descriptor: ANTISTASIN, CHLORIDE ION
Authors:Krengel, U, Dijkstra, B.W.
Deposit date:1997-04-16
Release date:1997-10-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structure of antistasin at 1.9 A resolution and its modelled complex with blood coagulation factor Xa.
EMBO J., 16, 1997
2B4G
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BU of 2b4g by Molmil
dihydroorotate dehydrogenase
Descriptor: BROMIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
Authors:Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-09-23
Release date:2005-10-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies
Mol.Microbiol., 68, 2008
2AR1
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BU of 2ar1 by Molmil
Structure of Hypothetical protein from Leishmania major
Descriptor: GLYCEROL, hypothetical protein
Authors:Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-08-18
Release date:2005-08-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Structure of Lmaj006129AAA, a hypothetical protein from Leishmania major.
Acta Crystallogr.,Sect.F, 62, 2006
2TDX
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BU of 2tdx by Molmil
DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL
Descriptor: DIPHTHERIA TOX REPRESSOR, NICKEL (II) ION
Authors:White, A, Ding, X, Zheng, H, Schiering, N, Ringe, D, Murphy, J.R.
Deposit date:1998-06-22
Release date:1998-10-14
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex.
Nature, 394, 1998
5DFR
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BU of 5dfr by Molmil
CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
Descriptor: CHLORIDE ION, DIHYDROFOLATE REDUCTASE
Authors:Bystroff, C, Kraut, J.
Deposit date:1988-10-21
Release date:1990-07-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding.
Biochemistry, 30, 1991
1BF3
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BU of 1bf3 by Molmil
P-HYDROXYBENZOATE HYDROXYLASE (PHBH) MUTANT WITH CYS 116 REPLACED BY SER (C116S) AND ARG 42 REPLACED BY LYS (R42K), IN COMPLEX WITH FAD AND 4-HYDROXYBENZOIC ACID
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID
Authors:Eppink, M.H.M, Schreuder, H.A, Van Berkel, W.J.H.
Deposit date:1998-05-26
Release date:1998-08-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Lys42 and Ser42 variants of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens reveal that Arg42 is essential for NADPH binding.
Eur.J.Biochem., 253, 1998
1BGJ
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BU of 1bgj by Molmil
P-HYDROXYBENZOATE HYDROXYLASE (PHBH) MUTANT WITH CYS 116 REPLACED BY SER (C116S) AND HIS 162 REPLACED BY ARG (H162R), IN COMPLEX WITH FAD AND 4-HYDROXYBENZOIC ACID
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID
Authors:Eppink, M.H.M, Schreuder, H.A, Van Berkel, W.J.H.
Deposit date:1998-05-29
Release date:1998-08-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Interdomain binding of NADPH in p-hydroxybenzoate hydroxylase as suggested by kinetic, crystallographic and modeling studies of histidine 162 and arginine 269 variants.
J.Biol.Chem., 273, 1998
1BGN
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BU of 1bgn by Molmil
P-HYDROXYBENZOATE HYDROXYLASE (PHBH) MUTANT WITH CYS 116 REPLACED BY SER (C116S) AND ARG 269 REPLACED BY THR (R269T), IN COMPLEX WITH FAD AND 4-HYDROXYBENZOIC ACID
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID
Authors:Eppink, M.H.M, Schreuder, H.A, Van Berkel, W.J.H.
Deposit date:1998-05-29
Release date:1998-08-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interdomain binding of NADPH in p-hydroxybenzoate hydroxylase as suggested by kinetic, crystallographic and modeling studies of histidine 162 and arginine 269 variants.
J.Biol.Chem., 273, 1998
1OJT
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BU of 1ojt by Molmil
STRUCTURE OF DIHYDROLIPOAMIDE DEHYDROGENASE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, SURFACE PROTEIN
Authors:Li De La Sierra, I, Prange, T, Pernot, L.
Deposit date:1996-09-06
Release date:1997-10-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Molecular structure of the lipoamide dehydrogenase domain of a surface antigen from Neisseria meningitidis.
J.Mol.Biol., 269, 1997
1MC0
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BU of 1mc0 by Molmil
Regulatory Segment of Mouse 3',5'-Cyclic Nucleotide Phosphodiesterase 2A, Containing the GAF A and GAF B Domains
Descriptor: 3',5'-cyclic nucleotide phosphodiesterase 2A, CYCLIC GUANOSINE MONOPHOSPHATE
Authors:Martinez, S, Wu, A, Glavas, N, Tang, X, Turley, S, Hol, W, Beavo, J.
Deposit date:2002-08-04
Release date:2002-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding.
Proc.Natl.Acad.Sci.USA, 99, 2002
1G8Z
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BU of 1g8z by Molmil
HIS57ALA MUTANT OF CHOLERA TOXIN B-PENATMER
Descriptor: CHOLERA TOXIN B PROTEIN, beta-D-galactopyranose
Authors:Aman, A.T, Fraser, S, Merritt, E.A, Rodigherio, C, Kenny, M.
Deposit date:2000-11-21
Release date:2001-07-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:A mutant cholera toxin B subunit that binds GM1- ganglioside but lacks immunomodulatory or toxic activity.
Proc.Natl.Acad.Sci.USA, 98, 2001
2MTA
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BU of 2mta by Molmil
CRYSTAL STRUCTURE OF A TERNARY ELECTRON TRANSFER COMPLEX BETWEEN METHYLAMINE DEHYDROGENASE, AMICYANIN AND A C-TYPE CYTOCHROME
Descriptor: AMICYANIN, COPPER (II) ION, CYTOCHROME C551I, ...
Authors:Chen, L, Mathews, F.S.
Deposit date:1993-10-26
Release date:1994-01-31
Last modified:2021-03-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of an electron transfer complex: methylamine dehydrogenase, amicyanin, and cytochrome c551i.
Science, 264, 1994
4DK6
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BU of 4dk6 by Molmil
Structure of Editosome protein
Descriptor: RNA-editing complex protein MP81, single domain antibody VHH
Authors:Park, Y.-J, Hol, W.
Deposit date:2012-02-03
Release date:2012-07-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.
Nucleic Acids Res., 40, 2012
4DNI
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BU of 4dni by Molmil
Structure of Editosome protein
Descriptor: Fusion protein of RNA-editing complex proteins MP42 and MP18
Authors:Park, Y.-J, Hol, W.
Deposit date:2012-02-08
Release date:2012-12-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Explorations of linked editosome domains leading to the discovery of motifs defining conserved pockets in editosome OB-folds.
J.Struct.Biol., 180, 2012
6DFR
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BU of 6dfr by Molmil
CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. THE NADP+ HOLOENZYME AND THE FOLATE(DOT)NADP+ TERNARY COMPLEX. SUBSTRATE BINDING AND A MODEL FOR THE TRANSITION STATE
Descriptor: CALCIUM ION, DIHYDROFOLATE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Bystroff, C, Oatley, S.J, Kraut, J.
Deposit date:1988-10-21
Release date:1990-07-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of Escherichia coli dihydrofolate reductase: the NADP+ holoenzyme and the folate.NADP+ ternary complex. Substrate binding and a model for the transition state.
Biochemistry, 29, 1990
1KEH
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BU of 1keh by Molmil
Precursor structure of cephalosporin acylase
Descriptor: precursor of cephalosporin acylase
Authors:Kim, Y, Kim, S.
Deposit date:2001-11-16
Release date:2002-05-16
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Precursor structure of cephalosporin acylase. Insights into autoproteolytic activation in a new N-terminal hydrolase family
J.Biol.Chem., 277, 2002
1THM
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BU of 1thm by Molmil
CRYSTAL STRUCTURE OF THERMITASE AT 1.4 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, SODIUM ION, SULFATE ION, ...
Authors:Teplyakov, A.V, Kuranova, I.P, Harutyunyan, E.H.
Deposit date:1992-02-24
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Crystal structure of thermitase at 1.4 A resolution.
J.Mol.Biol., 214, 1990

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