8VQN
| Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule 6R | Descriptor: | (S~1~S,3R)-N-{3-chloro-4-[(2S)-2-phenylmorpholine-4-carbonyl]phenyl}-3-(dimethylamino)pyrrolidine-1-sulfonimidoyl fluoride, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... | Authors: | Lin, T.H, Zhu, Y, Wilson, I.A. | Deposit date: | 2024-01-18 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VQL
| Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule 6S prime | Descriptor: | (S~1~S,3S)-N-{3,5-dichloro-4-[(2S)-2-phenylmorpholine-4-carbonyl]phenyl}-3-(dimethylamino)pyrrolidine-1-sulfonimidoyl fluoride, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, T.H, Zhu, Y, Wilson, I.A. | Deposit date: | 2024-01-18 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc.Natl.Acad.Sci.USA, 121, 2024
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8V2E
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5JOR
| Crystal structure of unbound anti-glycan antibody Fab14.22 at 2.2 A | Descriptor: | Fab 14.22 light chain, Fab14.22 heavy chain, GLYCEROL, ... | Authors: | Sarkar, A, Irimia, A, Teyton, L, Wilson, I.A. | Deposit date: | 2016-05-02 | Release date: | 2017-03-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.206 Å) | Cite: | T cells control the generation of nanomolar-affinity anti-glycan antibodies. J. Clin. Invest., 127, 2017
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8VBK
| Structure of bovine anti-HIV Fab ElsE5 | Descriptor: | Bovine Fab ElsE5 heavy chain, Bovine Fab ElsE5 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire To Be Published
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8VBM
| Structure of bovine anti-HIV Fab ElsE7 | Descriptor: | Bovine Fab ElsE7 heavy chain, Bovine Fab ElsE7 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire To Be Published
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8VBP
| Structure of bovine anti-HIV Fab Bess4 | Descriptor: | Bovine Fab Bess4 heavy chain, Bovine Fab Bess4 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire To Be Published
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8VBR
| Structure of bovine anti-HIV Fab ElsE11 | Descriptor: | Bovine Fab ElsE11 light chain, Bovine Fab Else11 heavy chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire To Be Published
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8V4I
| Structure of bovine anti-HIV Fab ElsE1 | Descriptor: | ElsE1 Fab heavy chain, ElsE1 Fab light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-11-29 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire To Be Published
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8VBJ
| Structure of bovine anti-HIV Fab ElsE2 | Descriptor: | Bovine Fab ElsE2 heavy chain, Bovine Fab ElsE2 light chain, POTASSIUM ION, ... | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire To Be Published
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8VBN
| Structure of bovine anti-HIV Fab ElsE8 | Descriptor: | Bovine Fab ElsE8 heavy chain, Bovine Fab ElsE8 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire To Be Published
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8VBO
| Structure of bovine anti-HIV Fab ElsE9 | Descriptor: | Bovine Fab ElsE9 heavy chain, Bovine Fab ElsE9 light chain, GLYCEROL, ... | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire To Be Published
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8VBQ
| Structure of bovine anti-HIV Fab Bess7 | Descriptor: | Bovine Fab Bess7 heavy chain, Bovine Fab Bess7 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire To Be Published
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8VBL
| Structure of bovine anti-HIV Fab ElsE6 | Descriptor: | Bovine Fab ElsE6 heavy chain, Bovine Fab ElsE6 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire To Be Published
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6W05
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6WG1
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6W00
| Crystal structure of Fab239 in complex with NPNA2 peptide from circumsporozoite protein | Descriptor: | Fab239 heavy chain, Fab239 light chain, Immunoglobulin G-binding protein G, ... | Authors: | Pholcharee, T, Oyen, D, Wilson, I.A. | Deposit date: | 2020-02-28 | Release date: | 2020-07-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.853 Å) | Cite: | Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum. Nat Commun, 12, 2021
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6WFX
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6WG0
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6WFW
| Crystal structure of Fab364 in complex with NPNA2 peptide from circumsporozoite protein | Descriptor: | Fab364 heavy chain, Fab364 light chain, Immunoglobulin G-binding protein G, ... | Authors: | Pholcharee, T, Oyen, D, Wilson, I.A. | Deposit date: | 2020-04-04 | Release date: | 2020-07-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.093 Å) | Cite: | Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum. Nat Commun, 12, 2021
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6WG2
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6WFZ
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6WFY
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4ZCJ
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5AWN
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