1NDF
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![BU of 1ndf by Molmil](/molmil-images/mine/1ndf) | Carnitine Acetyltransferase in Complex with Carnitine | Descriptor: | CARNITINE, Carnitine Acetyltransferase | Authors: | Jogl, G, Tong, L. | Deposit date: | 2002-12-09 | Release date: | 2003-01-28 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of Carnitine Acetyltransferase and Implications for the Catalytic Mechanism and Fatty Acid Transport Cell(Cambridge,Mass.), 112, 2003
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1NXU
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![BU of 1nxu by Molmil](/molmil-images/mine/1nxu) | CRYSTAL STRUCTURE OF E. COLI HYPOTHETICAL OXIDOREDUCTASE YIAK NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER82. | Descriptor: | Hypothetical oxidoreductase yiaK, SULFATE ION | Authors: | Forouhar, F, Lee, I, Benach, J, Kulkarni, K, Xiao, R, Acton, T.B, Shastry, R, Rost, B, Montelione, G.T, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-02-11 | Release date: | 2003-03-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Novel NAD-binding Protein Revealed by the Crystal Structure of 2,3-Diketo-L-gulonate Reductase (YiaK). J.Biol.Chem., 279, 2004
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1QR6
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![BU of 1qr6 by Molmil](/molmil-images/mine/1qr6) | HUMAN MITOCHONDRIAL NAD(P)-DEPENDENT MALIC ENZYME | Descriptor: | MALIC ENZYME 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Xu, Y, Bhargava, G, Wu, H, Loeber, G, Tong, L. | Deposit date: | 1999-06-18 | Release date: | 1999-07-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of human mitochondrial NAD(P)(+)-dependent malic enzyme: a new class of oxidative decarboxylases. Structure, 7, 1999
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1OYZ
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![BU of 1oyz by Molmil](/molmil-images/mine/1oyz) | X-RAY STRUCTURE OF YIBA_ECOLI NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ET31. | Descriptor: | Hypothetical protein yibA | Authors: | Kuzin, A, Semesi, A, Skarina, T, Savchenko, A, Arrowsmith, C, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-04-07 | Release date: | 2003-08-12 | Last modified: | 2018-04-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | X-RAY STRUCTURE OF YIBA_ECOLI NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ET31. To be Published
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1PJL
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![BU of 1pjl by Molmil](/molmil-images/mine/1pjl) | Crystal structure of human m-NAD-ME in ternary complex with NAD and Lu3+ | Descriptor: | LUTETIUM (III) ION, NAD-dependent malic enzyme, mitochondrial, ... | Authors: | Yang, Z, Batra, R, Floyd, D.L, Hung, H.-C, Chang, G.-G, Tong, L. | Deposit date: | 2003-06-03 | Release date: | 2003-06-17 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Potent and competitive inhibition of malic enzymes by lanthanide ions Biochem.Biophys.Res.Commun., 274, 2000
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1OD2
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![BU of 1od2 by Molmil](/molmil-images/mine/1od2) | Acetyl-CoA Carboxylase Carboxyltransferase Domain | Descriptor: | ACETYL COENZYME *A, ACETYL-COENZYME A CARBOXYLASE, ADENINE | Authors: | Zhang, H, Yang, Z, Shen, Y, Tong, L. | Deposit date: | 2003-02-12 | Release date: | 2003-04-03 | Last modified: | 2018-06-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase. Science, 299, 2003
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1NXH
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![BU of 1nxh by Molmil](/molmil-images/mine/1nxh) | X-RAY STRUCTURE: NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT87 | Descriptor: | MTH396 protein | Authors: | Khayat, R, Savchenko, A, Edwards, A, Arowsmith, C, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-02-10 | Release date: | 2004-02-24 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | X-RAY STRUCTURE OF MTH396 To be Published
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1CA9
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![BU of 1ca9 by Molmil](/molmil-images/mine/1ca9) | STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A PEPTIDE FROM TNF-R2 | Descriptor: | PROTEIN (TNF RECEPTOR ASSOCIATED FACTOR 2), PROTEIN (TNF-R2) | Authors: | Park, Y.C, Burkitt, V, Villa, A.R, Tong, L, Wu, H. | Deposit date: | 1999-02-25 | Release date: | 1999-04-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for self-association and receptor recognition of human TRAF2. Nature, 398, 1999
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1CA4
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![BU of 1ca4 by Molmil](/molmil-images/mine/1ca4) | STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 (TRAF2) | Descriptor: | PROTEIN (TNF RECEPTOR ASSOCIATED FACTOR 2) | Authors: | Park, Y.C, Burkitt, V, Villa, A.R, Tong, L, Wu, H. | Deposit date: | 1999-02-23 | Release date: | 1999-04-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for self-association and receptor recognition of human TRAF2. Nature, 398, 1999
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3TJU
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![BU of 3tju by Molmil](/molmil-images/mine/3tju) | Crystal structure of human granzyme H with an inhibitor | Descriptor: | Ac-PTSY-CMK inhibitor, Granzyme H, SULFATE ION | Authors: | Wang, L, Zhang, K, Wu, L, Tong, L, Sun, F, Fan, Z. | Deposit date: | 2011-08-25 | Release date: | 2011-12-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif J.Immunol., 188, 2012
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1AFV
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![BU of 1afv by Molmil](/molmil-images/mine/1afv) | HIV-1 CAPSID PROTEIN (P24) COMPLEX WITH FAB25.3 | Descriptor: | ANTIBODY FAB25.3 FRAGMENT (HEAVY CHAIN), ANTIBODY FAB25.3 FRAGMENT (LIGHT CHAIN), HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 CAPSID PROTEIN, ... | Authors: | Momany, C, Kovari, L.C, Prongay, A.J, Keller, W, Gitti, R.K, Lee, B.M, Gorbalenya, A.E, Tong, L, Mcclure, J, Ehrlich, L.S, Summers, M.F, Carter, C, Rossmann, M.G. | Deposit date: | 1997-03-14 | Release date: | 1997-08-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Crystal structure of dimeric HIV-1 capsid protein. Nat.Struct.Biol., 3, 1996
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4F67
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![BU of 4f67 by Molmil](/molmil-images/mine/4f67) | Three dimensional structure of the double mutant of UPF0176 protein lpg2838 from Legionella pneumophila at the resolution 1.8A, Northeast Structural Genomics Consortium (NESG) Target LgR82 | Descriptor: | UPF0176 protein lpg2838 | Authors: | Kuzin, A, Neely, H, Street, L, Odukwe, N, Seetharaman, J, Mao, M, Xiao, R, Kohan, E, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-05-14 | Release date: | 2012-05-30 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Three dimensional structure of the double mutant of UPF0176 protein lpg2838 from Legionella pneumophila at the resolution 1.8A, Northeast
Structural Genomics Consortium (NESG) Target LgR82 To be Published
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4DLH
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![BU of 4dlh by Molmil](/molmil-images/mine/4dlh) | Crystal Structure of the protein Q9HRE7 from Halobacterium salinarium at the resolution 1.9A, Northeast Structural Genomics Consortium (NESG) Target HsR50 | Descriptor: | uncharacterized protein | Authors: | Kuzin, A, Chen, Y, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-02-06 | Release date: | 2012-02-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Northeast Structural Genomics Consortium Target HsR50 To be Published
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1DO8
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![BU of 1do8 by Molmil](/molmil-images/mine/1do8) | CRYSTAL STRUCTURE OF A CLOSED FORM OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME | Descriptor: | MALIC ENZYME, MANGANESE (II) ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Yang, Z, Floyd, D.L, Loeber, G, Tong, L. | Deposit date: | 1999-12-19 | Release date: | 2000-03-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of a closed form of human malic enzyme and implications for catalytic mechanism. Nat.Struct.Biol., 7, 2000
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4FIB
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![BU of 4fib by Molmil](/molmil-images/mine/4fib) | Crystal structure of the ydhK protein from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR518A. | Descriptor: | Uncharacterized protein ydhK | Authors: | Vorobiev, S, Abashidze, M, Seetharaman, J, Mao, M, Xiao, R, Maglaqui, M, Owens, L.A, Cunningham, K, Zhao, L, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-06-08 | Release date: | 2012-06-20 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Crystal structure of the ydhK protein from Bacillus subtilis. To be Published
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4FLE
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![BU of 4fle by Molmil](/molmil-images/mine/4fle) | Crystal structure of the esterase YqiA (YE3661) from Yersinia enterocolitica, Northeast Structural Genomics Consortium Target YeR85 | Descriptor: | esterase | Authors: | Forouhar, F, Lew, S, Seetharaman, J, Shastry, R, Kohan, E, Maglaqui, M, Mao, L, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-06-14 | Release date: | 2012-08-08 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the esterase YqiA (YE3661) from Yersinia enterocolitica, Northeast Structural Genomics Consortium Target YeR85 (CASP Target) To be Published
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3TK9
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![BU of 3tk9 by Molmil](/molmil-images/mine/3tk9) | Crystal structure of human granzyme H | Descriptor: | Granzyme H, SULFATE ION | Authors: | Wang, L, Zhang, K, Wu, L, Tong, L, Sun, F, Fan, Z. | Deposit date: | 2011-08-25 | Release date: | 2011-12-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif J.Immunol., 188, 2012
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3TJV
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![BU of 3tjv by Molmil](/molmil-images/mine/3tjv) | Crystal structure of human granzyme H with a peptidyl substrate | Descriptor: | Granzyme H, PTSYAGDDSG, SULFATE ION | Authors: | Wang, L, Zhang, K, Wu, L, Tong, L, Sun, F, Fan, Z. | Deposit date: | 2011-08-25 | Release date: | 2011-12-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif J.Immunol., 188, 2012
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1BI7
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![BU of 1bi7 by Molmil](/molmil-images/mine/1bi7) | MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURE OF THE CDK6-P16INK4A TUMOR SUPPRESSOR COMPLEX | Descriptor: | CYCLIN-DEPENDENT KINASE 6, MULTIPLE TUMOR SUPPRESSOR | Authors: | Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P. | Deposit date: | 1998-06-22 | Release date: | 1999-01-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a. Nature, 395, 1998
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1BI8
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![BU of 1bi8 by Molmil](/molmil-images/mine/1bi8) | MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEX | Descriptor: | CYCLIN-DEPENDENT KINASE 6, CYCLIN-DEPENDENT KINASE INHIBITOR | Authors: | Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P. | Deposit date: | 1998-06-22 | Release date: | 1999-01-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a. Nature, 395, 1998
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4FFD
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![BU of 4ffd by Molmil](/molmil-images/mine/4ffd) | Crystal structure of engineered protein. northeast structural genomics consortium target or48 | Descriptor: | MAGNESIUM ION, PF00702 DOMAIN PROTEIN | Authors: | Seetharaman, J, Lew, S, Nivon, L, Baker, D, Bjelic, S, Ciccosanti, C, Sahdev, S, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-05-31 | Release date: | 2013-02-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Crystal structure of engineered protein. northeast structural genomics consortium target or48 To be Published
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4G63
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![BU of 4g63 by Molmil](/molmil-images/mine/4g63) | Crystal structure of cytosolic IMP-GMP specific 5'-nucleotidase (lpg0095) in complex with phosphate ions from Legionella pneumophila, Northeast Structural Genomics Consortium Target LgR1 | Descriptor: | Cytosolic IMP-GMP specific 5'-nucleotidase, PHOSPHATE ION | Authors: | Forouhar, F, Abashidze, M, Seetharaman, J, Ho, C.K, Ciccosanti, C, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-07-18 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila. Febs J., 281, 2014
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1EFL
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![BU of 1efl by Molmil](/molmil-images/mine/1efl) | HUMAN MALIC ENZYME IN A QUATERNARY COMPLEX WITH NAD, MG, AND TARTRONATE | Descriptor: | MAGNESIUM ION, MALIC ENZYME, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Yang, Z, Floyd, D.L, Loeber, G, Tong, L. | Deposit date: | 2000-02-09 | Release date: | 2000-03-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of a closed form of human malic enzyme and implications for catalytic mechanism. Nat.Struct.Biol., 7, 2000
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1EFK
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![BU of 1efk by Molmil](/molmil-images/mine/1efk) | STRUCTURE OF HUMAN MALIC ENZYME IN COMPLEX WITH KETOMALONATE | Descriptor: | ALPHA-KETOMALONIC ACID, MAGNESIUM ION, MALIC ENZYME, ... | Authors: | Yang, Z, Floyd, D.L, Loeber, G, Tong, L. | Deposit date: | 2000-02-09 | Release date: | 2000-03-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of a closed form of human malic enzyme and implications for catalytic mechanism. Nat.Struct.Biol., 7, 2000
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5TJA
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![BU of 5tja by Molmil](/molmil-images/mine/5tja) | I-II linker of TRPML1 channel at pH 6 | Descriptor: | Mucolipin-1 | Authors: | Li, M, Zhang, W.K, Benvin, N.M, Zhou, X, Su, D, Li, H, Wang, S, Michailidis, I.E, Tong, L, Li, X, Yang, J. | Deposit date: | 2016-10-04 | Release date: | 2017-01-25 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel. Nat. Struct. Mol. Biol., 24, 2017
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