3NMU
| Crystal Structure of substrate-bound halfmer box C/D RNP | Descriptor: | 50S ribosomal protein L7Ae, Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, NOP5/NOP56 related protein, ... | Authors: | Li, H, Xue, S, Wang, R. | Deposit date: | 2010-06-22 | Release date: | 2011-05-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.729 Å) | Cite: | Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle. Mol.Cell, 39, 2010
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7CKG
| Crystal structure of TMSiPheRS complexed with TMSiPhe | Descriptor: | 4-(trimethylsilyl)-L-phenylalanine, Tyrosine--tRNA ligase | Authors: | Sun, J.P, Wang, J.Y, Zhu, Z.L, He, Q.T, Xiao, P. | Deposit date: | 2020-07-17 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.053 Å) | Cite: | DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1 H-NMR probe. Nat Commun, 11, 2020
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7CKH
| Crystal structure of TMSiPheRS | Descriptor: | Tyrosine--tRNA ligase | Authors: | Sun, J.P, Wang, J.Y, Zhu, Z.L, He, Q.T, Xiao, P. | Deposit date: | 2020-07-17 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.79492676 Å) | Cite: | DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1 H-NMR probe. Nat Commun, 11, 2020
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3NVK
| Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle | Descriptor: | 50S ribosomal protein L7Ae, Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, NOP5/NOP56 related protein, ... | Authors: | Xue, S, Wang, R, Li, H. | Deposit date: | 2010-07-08 | Release date: | 2011-07-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.209 Å) | Cite: | Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle. Mol.Cell, 39, 2010
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3NVM
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3NVI
| Structure of N-terminal truncated Nop56/58 bound with L7Ae and box C/D RNA | Descriptor: | 50S ribosomal protein L7Ae, NOP5/NOP56 related protein, RNA (5'-R(*CP*UP*CP*UP*GP*AP*CP*CP*GP*AP*AP*AP*GP*GP*CP*GP*UP*GP*AP*UP*GP*AP*GP*C)-3') | Authors: | Li, H, Xue, S, Wang, R. | Deposit date: | 2010-07-08 | Release date: | 2011-07-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.709 Å) | Cite: | Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle. Mol.Cell, 39, 2010
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5B7J
| Structure model of Sap1-DNA complex | Descriptor: | DNA (5'-D(*AP*AP*TP*AP*TP*TP*GP*TP*TP*TP*TP*G)-3'), DNA (5'-D(*CP*AP*AP*AP*AP*CP*AP*AP*TP*AP*TP*T)-3'), Switch-activating protein 1 | Authors: | Jin, C, Hu, Y, Ding, J, Zhang, Y. | Deposit date: | 2016-06-07 | Release date: | 2017-02-22 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeast Schizosaccharomyces pombe J. Biol. Chem., 292, 2017
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7JVN
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7JVM
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5ENM
| Compound 10 | Descriptor: | (2~{R},4~{S},6~{S})-4-[2,4-bis(fluoranyl)-5-pyrimidin-5-yl-phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-1,3-thiazinan-2-amine, Beta-secretase 1, GLYCEROL, ... | Authors: | Lewis, H.A. | Deposit date: | 2015-11-09 | Release date: | 2016-10-05 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Targeting the BACE1 Active Site Flap Leads to a Potent Inhibitor That Elicits Robust Brain A beta Reduction in Rodents. Acs Med.Chem.Lett., 7, 2016
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5ENK
| Compound 18 | Descriptor: | (4~{S},6~{S})-4-[2,4-bis(fluoranyl)-5-pyrimidin-5-yl-phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine, Beta-secretase 1, GLYCEROL, ... | Authors: | Lewis, H.A. | Deposit date: | 2015-11-09 | Release date: | 2016-07-06 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Targeting the BACE1 Active Site Flap Leads to a Potent Inhibitor That Elicits Robust Brain A beta Reduction in Rodents. Acs Med.Chem.Lett., 7, 2016
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7FCV
| Cryo-EM structure of the Potassium channel AKT1 mutant from Arabidopsis thaliana | Descriptor: | PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, Potassium channel AKT1 | Authors: | Yang, G.H, Lu, Y.M, Jia, Y.T, Zhang, Y.M, Tang, R.F, Xu, X, Li, X.M, Lei, J.L. | Deposit date: | 2021-07-15 | Release date: | 2022-11-09 | Last modified: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis. Nat Commun, 13, 2022
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4EZ5
| CDK6 (monomeric) in complex with inhibitor | Descriptor: | Cyclin-dependent kinase 6, {5-[4-(dimethylamino)piperidin-1-yl]-1H-imidazo[4,5-b]pyridin-2-yl}[2-(isoquinolin-4-yl)pyridin-4-yl]methanone | Authors: | Chopra, R, Xu, M. | Deposit date: | 2012-05-02 | Release date: | 2013-02-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Fragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 Inhibitors. ACS Med Chem Lett, 3, 2012
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8JOU
| Fiber I and fiber-tail-adaptor of phage GP4 | Descriptor: | Virion-associated phage protein, rope protein of phage GP4 | Authors: | Liu, H, Chen, W. | Deposit date: | 2023-06-08 | Release date: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Asymmetric Structure of Podophage GP4 Reveals a Novel Architecture of Three Types of Tail Fibers. J.Mol.Biol., 435, 2023
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8JOV
| Portal-tail complex of phage GP4 | Descriptor: | Portal protein, Putative tail fiber protein, Virion associated protein, ... | Authors: | Liu, H, Chen, W. | Deposit date: | 2023-06-08 | Release date: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Asymmetric Structure of Podophage GP4 Reveals a Novel Architecture of Three Types of Tail Fibers. J.Mol.Biol., 435, 2023
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8JUL
| Cryo-EM structure of SIDT1 in complex with phosphatidic acid | Descriptor: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, SID1 transmembrane family member 1, ZINC ION | Authors: | Sun, C.R, Xu, D, Li, Q, Zhou, C.Z, Chen, Y. | Deposit date: | 2023-06-26 | Release date: | 2023-11-15 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Human SIDT1 mediates dsRNA uptake via its phospholipase activity. Cell Res., 34, 2024
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8JUN
| Cryo-EM structure of SIDT1 E555Q mutant | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SID1 transmembrane family member 1, ZINC ION | Authors: | Sun, C.R, Xu, D, Li, Q, Zhou, C.Z, Chen, Y. | Deposit date: | 2023-06-26 | Release date: | 2023-11-15 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (2.38 Å) | Cite: | Human SIDT1 mediates dsRNA uptake via its phospholipase activity. Cell Res., 34, 2024
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8KEE
| Cyanophage A-1(L) sheath-tube | Descriptor: | sheath, tube | Authors: | Yu, R.C, Li, Q, Zhou, C.Z. | Deposit date: | 2023-08-11 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structure of the intact tail machine of Anabaena myophage A-1(L). Nat Commun, 15, 2024
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8KEA
| Cyanophage A-1(L) baseplate-initiators | Descriptor: | baseplate gp16, central spike, hub, ... | Authors: | Yu, R.C, Li, Q, Zhou, C.Z. | Deposit date: | 2023-08-11 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Structure of the intact tail machine of Anabaena myophage A-1(L). Nat Commun, 15, 2024
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8KEC
| Cyanophage A-1(L) tail fiber | Descriptor: | Long tail fiber, short tail fiber | Authors: | Yu, R.C, Li, Q, Zhou, C.Z. | Deposit date: | 2023-08-11 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of the intact tail machine of Anabaena myophage A-1(L). Nat Commun, 15, 2024
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8KE9
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8K66
| Cryo-EM structure of Oryza sativa HKT2;1 at 2.5 angstrom | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Wang, X, Shen, X, Qu, Y, Wang, C, Shen, H. | Deposit date: | 2023-07-25 | Release date: | 2024-04-03 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | Structural insights into ion selectivity and transport mechanisms of Oryza sativa HKT2;1 and HKT2;2/1 transporters. Nat.Plants, 10, 2024
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8K69
| Cryo-EM structure of Oryza sativa HKT2;2/1 at 2.3 angstrom | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Wang, X, Shen, X, Qu, Y, Wang, C, Shen, H. | Deposit date: | 2023-07-25 | Release date: | 2024-04-03 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.33 Å) | Cite: | Structural insights into ion selectivity and transport mechanisms of Oryza sativa HKT2;1 and HKT2;2/1 transporters. Nat.Plants, 10, 2024
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8KEG
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8KEF
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