1UUY
| Structure of a molybdopterin-bound cnx1g domain links molybdenum and copper metabolism | Descriptor: | ADENOSINE MONOPHOSPHATE, COPPER (I) ION, FORMIC ACID, ... | Authors: | Kuper, J, Llamas, A, Hecht, H.J, Mendel, R.R, Schwarz, G. | Deposit date: | 2004-01-12 | Release date: | 2004-08-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of a Molybdopterin-Bound Cnx1G Domain Links Molybdenum and Copper Metabolism Nature, 430, 2004
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2IZ7
| structure of Moco Carrier Protein from Chlamydomonas reinhardtii | Descriptor: | MOCO CARRIER PROTEIN | Authors: | Fischer, K, Llamas, A, Tejada-Jimenez, M, Schrader, N, Kuper, J, Mendel, R.R, Fernandez, E, Schwarz, G. | Deposit date: | 2006-07-25 | Release date: | 2006-07-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Function and Structure of the Molybdenum Cofactor Carrier Protein from Chlamydomonas Reinhardtii. J.Biol.Chem., 281, 2006
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2IZ6
| Structure of the Chlamydomonas rheinhardtii Moco Carrier Protein | Descriptor: | MOLYBDENUM COFACTOR CARRIER PROTEIN | Authors: | Fischer, K, Llamas, A, Tejada-Jimenez, M, Schrader, N, Kuper, J, Mendel, R.R, Fernandez, E, Schwarz, G. | Deposit date: | 2006-07-25 | Release date: | 2006-07-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Function and Structure of the Molybdenum Cofactor Carrier Protein from Chlamydomonas Reinhardtii. J.Biol.Chem., 281, 2006
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8JZ0
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8JZ1
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2IZ5
| FUNCTION AND STRUCTURE OF THE MOLYBDENUM COFACTOR CARRIER PROTEIN MCP FROM CHLAMYDOMONAS REINHARDTII | Descriptor: | MOCO CARRIER PROTEIN | Authors: | Fischer, K, Llamas, A, Tejada-Jimenez, M, Schrader, N, Kuper, J, Mendel, R.R, Fernandez, E, Schwarz, G. | Deposit date: | 2006-07-25 | Release date: | 2006-07-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Function and Structure of the Molybdenum Cofactor Carrier Protein from Chlamydomonas Reinhardtii. J.Biol.Chem., 281, 2006
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4LHD
| Crystal structure of Synechocystis sp. PCC 6803 glycine decarboxylase (P-protein), holo form with pyridoxal-5'-phosphate and glycine, closed flexible loop | Descriptor: | 1,2-ETHANEDIOL, BICARBONATE ION, GLYCINE, ... | Authors: | Hasse, D, Andersson, E, Carlsson, G, Masloboy, A, Hagemann, M, Bauwe, H, Andersson, I. | Deposit date: | 2013-07-01 | Release date: | 2013-10-16 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.7959 Å) | Cite: | Structure of the Homodimeric Glycine Decarboxylase P-protein from Synechocystis sp. PCC 6803 Suggests a Mechanism for Redox Regulation. J.Biol.Chem., 288, 2013
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4LGL
| Crystal Structure of Glycine Decarboxylase P-protein from Synechocystis sp. PCC 6803, apo form | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Glycine dehydrogenase [decarboxylating] | Authors: | Hasse, D, Andersson, E, Carlsson, G, Masloboy, A, Hagemann, M, Bauwe, H, Andersson, I. | Deposit date: | 2013-06-28 | Release date: | 2013-10-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.0004 Å) | Cite: | Structure of the Homodimeric Glycine Decarboxylase P-protein from Synechocystis sp. PCC 6803 Suggests a Mechanism for Redox Regulation. J.Biol.Chem., 288, 2013
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4LHC
| Crystal structure of Synechocystis sp. PCC 6803 glycine decarboxylase (P-protein), holo form with pyridoxal-5'-phosphate and glycine | Descriptor: | 1,2-ETHANEDIOL, BICARBONATE ION, BICINE, ... | Authors: | Hasse, D, Andersson, E, Carlsson, G, Masloboy, A, Hagemann, M, Bauwe, H, Andersson, I. | Deposit date: | 2013-07-01 | Release date: | 2013-10-16 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.899 Å) | Cite: | Structure of the Homodimeric Glycine Decarboxylase P-protein from Synechocystis sp. PCC 6803 Suggests a Mechanism for Redox Regulation. J.Biol.Chem., 288, 2013
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1J1E
| Crystal structure of the 52kDa domain of human cardiac troponin in the Ca2+ saturated form | Descriptor: | CALCIUM ION, Troponin C, Troponin I, ... | Authors: | Takeda, S, Yamashita, A, Maeda, K, Maeda, Y. | Deposit date: | 2002-12-03 | Release date: | 2003-07-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of the core domain of human cardiac troponin in the Ca2+-saturated form Nature, 424, 2003
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4D4L
| human PFKFB3 in complex with a pyrrolopyrimidone compound | Descriptor: | 5-(4-chlorophenyl)-7-phenyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, 6-O-phosphono-beta-D-fructofuranose, 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 3, ... | Authors: | Stgallay, S.A, Bennett, N, Critchlow, S, Davies, G, Debreczeni, J.E, Evans, N, Holdgate, G, Jones, N.P, Leach, L, Maman, S, McLoughlin, S, Preston, M, Rigoreau, L, Thomas, A, Walker, G, Walsch, J, Ward, R.A, Wheatley, E, Winter, J. | Deposit date: | 2014-10-29 | Release date: | 2016-01-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.16 Å) | Cite: | Identifying a Novel Series of Pfkfb3 Inhibitors as a Metabolic Approach to Treating Cancer from Hts, Biophysical and Biochemical Methods To be Published
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4D4K
| human PFKFB3 in complex with a pyrrolopyrimidone compound | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 3, 7-(4-methoxyphenyl)-5-phenyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, ... | Authors: | Stgallay, S.A, Bennett, N, Critchlow, S, Davies, G, Debreczeni, J.E, Evans, N, Holdgate, G, Jones, N.P, Leach, L, Maman, S, McLoughlin, S, Preston, M, Rigoreau, L, Thomas, A, Walker, G, Walsch, J, Ward, R.A, Wheatley, E, Winter, J. | Deposit date: | 2014-10-29 | Release date: | 2016-01-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.24 Å) | Cite: | Identifying a Novel Series of Pfkfb3 Inhibitors as a Metabolic Approach to Treating Cancer from Hts, Biophysical and Biochemical Methods To be Published
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4D4M
| human PFKFB3 in complex with a pyrrolopyrimidone compound | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 3, 7-(4-bromophenyl)-5-phenyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, ... | Authors: | Stgallay, S.A, Bennett, N, Critchlow, S, Davies, G, Debreczeni, J.E, Evans, N, Holdgate, G, Jones, N.P, Leach, L, Maman, S, McLoughlin, S, Preston, M, Rigoreau, L, Thomas, A, Walker, G, Walsch, J, Ward, R.A, Wheatley, E, Winter, J. | Deposit date: | 2014-10-29 | Release date: | 2016-01-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Identifying a Novel Series of Pfkfb3 Inhibitors as a Metabolic Approach to Treating Cancer from Hts, Biophysical and Biochemical Methods To be Published
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4D4J
| human PFKFB3 in complex with a pyrrolopyrimidone compound | Descriptor: | 5-(4-bromophenyl)-7-phenyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, 6-O-phosphono-beta-D-fructofuranose, 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 3, ... | Authors: | Stgallay, S.A, Bennett, N, Critchlow, S, Davies, G, Debreczeni, J.E, Evans, N, Holdgate, G, Jones, N.P, Leach, L, Maman, S, McLoughlin, S, Preston, M, Rigoreau, L, Thomas, A, Walker, G, Walsch, J, Ward, R.A, Wheatley, E, Winter, J. | Deposit date: | 2014-10-29 | Release date: | 2016-01-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Identifying a Novel Series of Pfkfb3 Inhibitors as a Metabolic Approach to Treating Cancer from Hts, Biophysical and Biochemical Methods To be Published
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1KU9
| X-ray Structure of a Methanococcus jannaschii DNA-Binding Protein: Implications for Antibiotic Resistance in Staphylococcus aureus | Descriptor: | hypothetical protein MJ223 | Authors: | Ray, S.S, Bonanno, J.B, Chen, H, de Lencastre, H, Wu, S, Tomasz, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2002-01-21 | Release date: | 2002-12-25 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | X-ray structure of an M. jannaschii DNA-binding protein: implications for antibiotic resistance in S.
aureus Proteins, 50, 2002
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1J1D
| Crystal structure of the 46kDa domain of human cardiac troponin in the Ca2+ saturated form | Descriptor: | CALCIUM ION, Troponin C, Troponin I, ... | Authors: | Takeda, S, Yamashita, A, Maeda, K, Maeda, Y. | Deposit date: | 2002-12-03 | Release date: | 2003-07-15 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structure of the core domain of human cardiac troponin in the Ca2+-saturated form Nature, 424, 2003
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1GXW
| the 2.2 A resolution structure of thermolysin crystallized in presence of potassium thiocyanate | Descriptor: | CALCIUM ION, LYSINE, THERMOLYSIN, ... | Authors: | Gaucher, J.F, Selkti, M, Prange, T, Tomas, A. | Deposit date: | 2002-04-12 | Release date: | 2002-12-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | The 2.2 A Resolution Structure of Thermolysin (Tln) Crystallized in the Presence of Potassium Thiocyanate. Acta Crystallogr.,Sect.D, 58, 2002
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3B8Z
| High Resolution Crystal Structure of the Catalytic Domain of ADAMTS-5 (Aggrecanase-2) | Descriptor: | CALCIUM ION, N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide, ZINC ION, ... | Authors: | Shieh, H.-S, Williams, J.M, Mathis, K.J, Tortorella, M.D, Tomasselli, A. | Deposit date: | 2007-11-02 | Release date: | 2007-12-11 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | High resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2). J.Biol.Chem., 283, 2008
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3HVL
| Tethered PXR-LBD/SRC-1p complexed with SR-12813 | Descriptor: | Pregnane X receptor, Linker, Steroid receptor coactivator 1, ... | Authors: | Lesburg, C.A, Wang, W, Prosise, W.W, Chen, J, Taremi, S.S, Le, H.V, Madison, V, Cui, X, Thomas, A, Cheng, K.C. | Deposit date: | 2009-06-16 | Release date: | 2009-08-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Construction and characterization of a fully active PXR/SRC-1 tethered protein with increased stability Protein Eng.Des.Sel., 21, 2008
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1ZZA
| Solution NMR Structure of the Membrane Protein Stannin | Descriptor: | Stannin | Authors: | Buck-Koehntop, B.A, Mascioni, A, Buffy, J.J, Veglia, G. | Deposit date: | 2005-06-13 | Release date: | 2005-12-20 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure, dynamics, and membrane topology of stannin: a mediator of neuronal cell apoptosis induced by trimethyltin chloride. J.Mol.Biol., 354, 2005
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2AE1
| TROPINONE REDUCTASE-II | Descriptor: | TROPINONE REDUCTASE-II | Authors: | Nakajima, K, Yamashita, A, Akama, H, Nakatsu, T, Kato, H, Hashimoto, T, Oda, J, Yamada, Y. | Deposit date: | 1997-10-27 | Release date: | 1998-11-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of two tropinone reductases: different reaction stereospecificities in the same protein fold. Proc.Natl.Acad.Sci.USA, 95, 1998
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5JGE
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5JH9
| Crystal structure of prApe1 | Descriptor: | CACODYLATE ION, Vacuolar aminopeptidase 1, ZINC ION | Authors: | Noda, N.N, Adachi, W, Inagaki, F. | Deposit date: | 2016-04-20 | Release date: | 2016-06-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Basis for Receptor-Mediated Selective Autophagy of Aminopeptidase I Aggregates Cell Rep, 16, 2016
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5JGF
| Crystal structure of mApe1 | Descriptor: | Vacuolar aminopeptidase 1, ZINC ION | Authors: | Noda, N.N, Adachi, W, Inagaki, F. | Deposit date: | 2016-04-20 | Release date: | 2016-06-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural Basis for Receptor-Mediated Selective Autophagy of Aminopeptidase I Aggregates Cell Rep, 16, 2016
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7JKB
| 2xVH Fab | Descriptor: | Anti-Her2, Anti-lysozyme | Authors: | Lord, D.M, Zhou, Y.F. | Deposit date: | 2020-07-28 | Release date: | 2020-11-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Bringing the Heavy Chain to Light: Creating a Symmetric, Bivalent IgG-Like Bispecific. Antibodies, 9, 2020
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