5IS0
Structure of TRPV1 in complex with capsazepine, determined in lipid nanodisc
Summary for 5IS0
| Entry DOI | 10.2210/pdb5is0/pdb |
| Related | 5IRX 5IRZ |
| EMDB information | 8117 8118 8119 8120 |
| Descriptor | Transient receptor potential cation channel subfamily V member 1, capsazepine (2 entities in total) |
| Functional Keywords | trp, ion channel, nanodisc, vanilloid, lipid, interaction, transport protein |
| Biological source | Rattus norvegicus (Rat) More |
| Total number of polymer chains | 4 |
| Total formula weight | 293344.79 |
| Authors | Gao, Y.,Cao, E.,Julius, D.,Cheng, Y. (deposition date: 2016-03-15, release date: 2016-05-25, Last modification date: 2024-03-06) |
| Primary citation | Gao, Y.,Cao, E.,Julius, D.,Cheng, Y. TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action. Nature, 534:347-351, 2016 Cited by PubMed: 27281200DOI: 10.1038/nature17964 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.43 Å) |
Structure validation
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