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5IS0

Structure of TRPV1 in complex with capsazepine, determined in lipid nanodisc

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1C, B, D, ETransient receptor potential cation channel subfamily V member 1polymer63672959.34UniProt (O35433)
Pfam (PF00023)
Pfam (PF00520)
In PDB
Rattus norvegicus (Rat)TrpV1, Capsaicin receptor, Osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, Vanilloid receptor type 1-like
2C, B, D, Ecapsazepinenon-polymer376.94Chemie (6ET)
Sequence modifications
C, B, D, E: 110 - 603 (UniProt: O35433)
PDBExternal DatabaseDetails
Ala 106-expression tag
Met 107-expression tag
Gly 108-expression tag
Ser 109-expression tag
C, B, D, E: 627 - 764 (UniProt: O35433)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight291837.2
Non-Polymers*Number of molecules4
Total formula weight1507.6
All*Total formula weight293344.8
*Water molecules are not included.

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PDB entries from 2024-03-27

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