5IS0
Structure of TRPV1 in complex with capsazepine, determined in lipid nanodisc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (C, B, D, E) | Transient receptor potential cation channel subfamily V member 1 | polymer | 636 | 72959.3 | 4 | UniProt (O35433) Pfam (PF00023) Pfam (PF00520) | Rattus norvegicus (Rat) | TrpV1, Capsaicin receptor, Osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, Vanilloid receptor type 1-like |
| 2 | E, F, G, H (C, B, D, E) | capsazepine | non-polymer | 376.9 | 4 | Chemie (6ET) |
Sequence modifications
C, B, D, E: 110 - 603 (UniProt: O35433)
C, B, D, E: 627 - 764 (UniProt: O35433)
| PDB | External Database | Details |
|---|---|---|
| Ala 106 | - | expression tag |
| Met 107 | - | expression tag |
| Gly 108 | - | expression tag |
| Ser 109 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 291837.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1507.6 | |
| All* | Total formula weight | 293344.8 |
