2X0B
Crystal structure of human angiotensinogen complexed with renin
Summary for 2X0B
Entry DOI | 10.2210/pdb2x0b/pdb |
Related | 2WXW 2WXX 2WXY 2WXZ 2WY0 2WY1 |
Descriptor | RENIN, ANGIOTENSINOGEN (2 entities in total) |
Functional Keywords | hydrolase-hormone complex, hydrolase hormone complex, vasoconstrictor, glycoprotein, hypertension, serpins, zymogen, hydrolase, vasoactive, hydrolase/hormone |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted: P00797 P01019 |
Total number of polymer chains | 8 |
Total formula weight | 368687.46 |
Authors | Zhou, A.,Wei, Z.,Yan, Y.,Carrell, R.W.,Read, R.J. (deposition date: 2009-12-08, release date: 2010-10-20, Last modification date: 2023-12-20) |
Primary citation | Zhou, A.,Carrell, R.W.,Murphy, M.P.,Wei, Z.,Yan, Y.,Stanley, P.L.,Stein, P.E.,Pipkin, F.B.,Read, R.J. A Redox Switch in Angiotensinogen Modulates Angiotensin Release. Nature, 468:108-, 2010 Cited by PubMed: 20927107DOI: 10.1038/NATURE09505 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.33 Å) |
Structure validation
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