1HRN
HIGH RESOLUTION CRYSTAL STRUCTURES OF RECOMBINANT HUMAN RENIN IN COMPLEX WITH POLYHYDROXYMONOAMIDE INHIBITORS
Summary for 1HRN
| Entry DOI | 10.2210/pdb1hrn/pdb |
| Descriptor | RENIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, (2R,4S,5S)-N-[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]-2-(cyclopropylmethyl)-4,5-dihydroxy-6-phenylhexanamide, ... (4 entities in total) |
| Functional Keywords | aspartic proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 75329.03 |
| Authors | Tong, L.,Anderson, P.C. (deposition date: 1995-03-31, release date: 1995-06-03, Last modification date: 2020-07-29) |
| Primary citation | Tong, L.,Pav, S.,Lamarre, D.,Pilote, L.,LaPlante, S.,Anderson, P.C.,Jung, G. High resolution crystal structures of recombinant human renin in complex with polyhydroxymonoamide inhibitors. J.Mol.Biol., 250:211-222, 1995 Cited by PubMed: 7608971DOI: 10.1006/jmbi.1995.0372 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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