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1HRN

HIGH RESOLUTION CRYSTAL STRUCTURES OF RECOMBINANT HUMAN RENIN IN COMPLEX WITH POLYHYDROXYMONOAMIDE INHIBITORS

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
RENINpolymer33736939.62UniProt (P00797)
Pfam (PF00026)
Homo sapiens (human)
2C, F
(A, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
3D, E
(A, B)
(2R,4S,5S)-N-[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]-2-(cyclopropylmethyl)-4,5-dihydroxy-6-phenylhexanamidenon-polymer503.72Chemie (03D)
4G, H
(A, B)
waterwater18.0366Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight73879.2
Non-Polymers*Number of molecules4
Total formula weight1449.8
All*Total formula weight75329.0
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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