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9ZXC

Structure of AT118-R nanobody in complex with the angiotensin II type I receptor bound to losartan

Summary for 9ZXC
Entry DOI10.2210/pdb9zxc/pdb
EMDB information74919
DescriptorNanobody AT118-R,Type-1 angiotensin II receptor with Soluble cytochrome b562 insertion, BAG2 Anti-BRIL Fab Heavy Chain, BAG2 Anti-BRIL Fab Light Chain, ... (5 entities in total)
Functional Keywordsgpcr, nanobody, membrane protein
Biological sourcesynthetic construct
More
Total number of polymer chains3
Total formula weight114866.66
Authors
Skiba, M.A.,Gilman, M.S.A.,Kruse, A.C. (deposition date: 2026-01-03, release date: 2026-07-29)
Primary citationSkiba, M.A.,Liu, J.,Shen, P.,Kim, J.,Wren, E.,Gilman, M.S.A.,Staus, D.,McMahon, C.,Smith, J.S.,Lefkowitz, R.J.,Kahne, D.,Wingler, L.M.,Kruse, A.C.
Activation of the angiotensin II type I receptor by a non-peptide agonist
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.4 Å)
Structure validation

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PDB entries from 2026-07-29

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