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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9ZXC

Structure of AT118-R nanobody in complex with the angiotensin II type I receptor bound to losartan

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues22
DetailsRegion: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues13
DetailsCompositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues2
DetailsBinding site: {"description":"axial binding residue"}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues29
DetailsTransmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"25913193","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26420482","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30639100","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32079768","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YAY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS2","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues5
DetailsTopological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"25913193","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26420482","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30639100","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32079768","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YAY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS2","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues27
DetailsTransmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"25913193","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26420482","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30639100","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32079768","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YAY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS2","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues32
DetailsTopological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"25913193","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26420482","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30639100","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32079768","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YAY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS2","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues26
DetailsTransmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"25913193","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26420482","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30639100","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32079768","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YAY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS2","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues23
DetailsTransmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"25913193","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26420482","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30639100","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32079768","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YAY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS2","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues25
DetailsTransmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"25913193","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26420482","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30639100","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32079768","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YAY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS2","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues28
DetailsTransmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"25913193","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26420482","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YAY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUD","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues9
DetailsTopological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"25913193","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26420482","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YAY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUD","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI13
Number of Residues25
DetailsTransmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"25913193","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26420482","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YAY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUD","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI14
Number of Residues5
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"30639100","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"32079768","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6DO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS0","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI15
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"30639100","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32079768","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OS0","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI16
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

257179

PDB entries from 2026-07-29

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