9ZB7

A DARPin fused to the 1TEL crystallization chaperone via a direct helical fusion

Summary for 9ZB7

• Entry DOI: 10.2210/pdb9zb7/pdb
• Descriptor: Transcription factor ETV6,DARPin, 2-OXOGLUTARIC ACID, AMMONIUM ION, ... (9 entities in total)
• Functional Keywords: sterile alpha motif (sam) of human translocation ets leukemia (tel), protein crystallization chaperone, telsam, etv6, transcription, 1tel crystallization chaperone, oncoprotein, darpin, designed ankyrin repeat protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 1
• Total formula weight: 28286.36

Authors

Averett, J.C.,Bradford, M.J.,Wilson, E.W.,Averett, B.J.,Anderson, E.,Anderson, A.,Doukov, T.,Moody, J.D. (deposition date: 2025-11-20, release date: 2025-12-17)

• Primary citation: Averett, J.C.,Bradford, M.J.,Wilson, E.W.,Yseng, Y.J.,Averett, B.J.,Anderson, E.,Anderson, A.,Doukov, T.,Moody, J.D.; Polymer crystallization physics discovered through modulating the pH sensitivity of the TELSAM crystallization chaperone for increased solubility; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.24 Å)