9ZB7

A DARPin fused to the 1TEL crystallization chaperone via a direct helical fusion

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Transcription factor ETV6,DARPin	polymer	243	27093.3	1	UniProt (P41212) Pfam (PF02198)	Homo sapiens (human)	ETS translocation variant 6,ETS-related protein Tel1,Tel
2	B (A)	2-OXOGLUTARIC ACID	non-polymer		146.1	1	Chemie (AKG)
3	C (A)	AMMONIUM ION	non-polymer		18.0	1	Chemie (NH4)
4	D, E (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	F, G (A)	ETHANOL	non-polymer		46.1	2	Chemie (EOH)
6	H, I, J, K, L (A)	POTASSIUM ION	non-polymer		39.1	5	Chemie (K)
7	M, N, O, P, Q (A)	CHLORIDE ION	non-polymer		35.5	5	Chemie (CL)
8	R, S, T, U (A)	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
9	V (A)	water	water		18.0	205	Chemie (HOH)

Sequence modifications

A: 13 - 87 (UniProt: P41212)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
Glu 78	Val 112	engineered mutation

A: 88 - 243 (PDB: 9ZB7)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	27093.3
Non-Polymers*	Number of molecules	20
	Total formula weight	1193.1
All*	Total formula weight	28286.4

*Water molecules are not included.