9Z0E

Structure of disulfide-crosslinked S. cerevisiae Hrd1 dimer bound to one copy of Hrd3 in MSP1D1 nanodisc

Summary for 9Z0E

• Entry DOI: 10.2210/pdb9z0e/pdb
• EMDB information: 73699
• Descriptor: ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3 (2 entities in total)
• Functional Keywords: membrane protein, hrd1 ubiquitin ligase, hrd3, msp1d1 nanodisc
• Biological source: Saccharomyces cerevisiae (brewer's yeast); More
• Total number of polymer chains: 3
• Total formula weight: 174045.47

Authors

Pisa, R.,Rapoport, T.A. (deposition date: 2025-10-31, release date: 2026-01-14)

• Primary citation: Pisa, R.,Rapoport, T.A.; Lipid bilayer thinning near a ubiquitin ligase selects ER membrane proteins for degradation; bioarchive, 2025; DOI: 10.1101/2025.10.31.685944

Experimental method

ELECTRON MICROSCOPY (3.7 Å)