9YXQ

Cryo-EM structure of the Xenopus laevis mitotic centromere-associated kinesin (MCAK) bound to the paclitaxel-stabilized microtubule

Summary for 9YXQ

• Entry DOI: 10.2210/pdb9yxq/pdb
• Related: 9N9E 9N9F 9N9G 9N9H 9N9I
• EMDB information: 49166 49167 49168 49169 49170 73614
• Descriptor: Tubulin alpha-1B chain, Tubulin beta chain, Kinesin-like protein KIF2C, ... (7 entities in total)
• Functional Keywords: microtubule, mcak, kinesin, mitosis, cell cycle
• Biological source: Xenopus laevis (African clawed frog); More
• Total number of polymer chains: 14
• Total formula weight: 779305.90

Authors

Funabiki, H.,Niu, Y. (deposition date: 2025-10-27, release date: 2026-02-04)

• Primary citation: Funabiki, H.,Niu, Y.; Cryo-EM structure of the human Hec1-Nuf2 dimer bound to the paclitaxel-stabilized microtubule; Sci Adv, 2026

Experimental method

ELECTRON MICROSCOPY (3.39 Å)