9VEF

The cryo-EM structure of human Piezo2-MDFIC complex (composite map)

Summary for 9VEF

• Entry DOI: 10.2210/pdb9vef/pdb
• EMDB information: 65006
• Descriptor: Piezo-type mechanosensitive ion channel component 2,Green fluorescent protein, MyoD family inhibitor domain-containing protein (2 entities in total)
• Functional Keywords: piezo2, mechanosensitive channel, mdfic, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 1129848.69

Authors

Zhang, Y.,Dai, F. (deposition date: 2025-06-09, release date: 2026-04-08)

• Primary citation: Zhang, Y.,Dai, F.; MDFIC2 is a sensory neuron-specific PIEZO channel auxiliary subunit; Proc.Natl.Acad.Sci.USA, 2026

Experimental method

ELECTRON MICROSCOPY (3.75 Å)