9VEF
The cryo-EM structure of human Piezo2-MDFIC complex (composite map)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Piezo-type mechanosensitive ion channel component 2,Green fluorescent protein | polymer | 3020 | 348501.7 | 3 | UniProt (Q9H5I5) UniProt (P42212) | Homo sapiens (human) | Protein FAM38B |
| 2 | B, D, F (B, D, F) | MyoD family inhibitor domain-containing protein | polymer | 267 | 28114.6 | 3 | UniProt (Q9P1T7) | Homo sapiens (human) | I-mfa domain-containing protein,hIC |
Sequence modifications
A, C, E: 1 - 2752 (UniProt: Q9H5I5)
A, C, E: 2770 - 3006 (UniProt: P42212)
B, D, F: 1 - 246 (UniProt: Q9P1T7)
| PDB | External Database | Details |
|---|---|---|
| Ser 2753 | - | linker |
| Asn 2754 | - | linker |
| Ser 2755 | - | linker |
| Leu 2756 | - | linker |
| Glu 2757 | - | linker |
| Val 2758 | - | linker |
| Leu 2759 | - | linker |
| Phe 2760 | - | linker |
| Gln 2761 | - | linker |
| Gly 2762 | - | linker |
| Pro 2763 | - | linker |
| Thr 2764 | - | linker |
| Ala 2765 | - | linker |
| Ala 2766 | - | linker |
| Ala 2767 | - | linker |
| Ala 2768 | - | linker |
| Val 2769 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Leu 2832 | Phe 64 | conflict |
| Thr 2833 | Ser 65 | conflict |
| Lys 2974 | Ala 206 | conflict |
| Leu 2999 | His 231 | conflict |
| Ser 3007 | - | expression tag |
| Gly 3008 | - | expression tag |
| Gly 3009 | - | expression tag |
| Gly 3010 | - | expression tag |
| His 3011 | - | expression tag |
| His 3012 | - | expression tag |
| His 3013 | - | expression tag |
| His 3014 | - | expression tag |
| His 3015 | - | expression tag |
| His 3016 | - | expression tag |
| His 3017 | - | expression tag |
| His 3018 | - | expression tag |
| His 3019 | - | expression tag |
| His 3020 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -20 | - | initiating methionine |
| Asp -19 | - | expression tag |
| Tyr -18 | - | expression tag |
| Lys -17 | - | expression tag |
| Asp -16 | - | expression tag |
| Asp -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Lys -12 | - | expression tag |
| Gly -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Glu -9 | - | expression tag |
| Val -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Phe -6 | - | expression tag |
| Gln -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 1129848.7 | |
| All* | Total formula weight | 1129848.7 |
