9RX4

VPS34-CI bound to NRBF2 and RAB1A

Summary for 9RX4

• Entry DOI: 10.2210/pdb9rx4/pdb
• EMDB information: 54311 54357
• Descriptor: Phosphatidylinositol 3-kinase catalytic subunit type 3, ZINC ION, GUANOSINE-5'-TRIPHOSPHATE, ... (11 entities in total)
• Functional Keywords: lipid kinase, gtpase, kinase, autophagy, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 474768.28

Authors

Spokaite, S.,Ohashi, Y.,Dessus, A.N.,Bourguet, M.,Williams, R.L. (deposition date: 2025-07-10, release date: 2026-07-22)

• Primary citation: Spokaite, S.,Ohashi, Y.,Dessus, A.N.,Bourguet, M.,Williams, R.L.; When VPS34 complexes double down: Two RAB5s for VPS34-CII, two RAB1s for NRBF2-dimerized VPS34-CI; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.67 Å)