9RWZ
ZSWIM8-CUL3 complex bound to AGO2-miR-7-CYRANO
Summary for 9RWZ
| Entry DOI | 10.2210/pdb9rwz/pdb |
| EMDB information | 54352 |
| Descriptor | Protein argonaute-2, Elongin-B, Elongin-C, ... (8 entities in total) |
| Functional Keywords | mirna, e3 ligase, ligase |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 11 |
| Total formula weight | 689955.60 |
| Authors | Farnung, J.,Slobodyanyuk, E.,Bartel, D.P.,Schulman, B.A. (deposition date: 2025-07-10, release date: 2026-03-18) |
| Primary citation | Farnung, J.,Slobodyanyuk, E.,Wang, P.Y.,Lin, D.H.,Blodgett, L.A.,Schulman, B.A.,Bartel, D.P. E3 ligase mechanism of target-directed microRNA degradation To Be Published, |
| Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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