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9R6S

Prefusion stabilized spike glycoprotein of human coronavirus OC43.

Summary for 9R6S
Entry DOI10.2210/pdb9r6s/pdb
EMDB information53686 53687
DescriptorSpike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywordsfusion glycoprotein, membrane protein, viral protein
Biological sourceHuman coronavirus OC43
Total number of polymer chains3
Total formula weight447729.92
Authors
Melchers, J.M.,Hulswit, R.J.G.,Hurdiss, D.L. (deposition date: 2025-05-13, release date: 2026-03-11)
Primary citationMelchers, J.M.,Juraszek, J.,Hulswit, R.J.G.,van Overveld, D.,Le, L.,van Kuppeveld, F.,Hurdiss, D.L.,Bosch, B.J.,Langedijk, J.P.M.,Bakkers, M.J.G.
AI-guided prefusion stabilization of the human coronavirus OC43 spike protein enables universal Embecovirus antigen design.
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.1 Å)
Structure validation

250359

PDB entries from 2026-03-11

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