9O6B

X-Ray structure of F240L mutant HOXB13 in complex with DNA (CAA)

Summary for 9O6B

• Entry DOI: 10.2210/pdb9o6b/pdb
• Descriptor: Homeobox protein Hox-B13, DNA-TTGTGTTTTATTGGGTCC, DNA-GGACCCAATAAAACACAA, ... (4 entities in total)
• Functional Keywords: hoxb13, prostate cancer, germline, mutation, homeobox, dna-binding, transcription factor, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 45293.46

Authors

Dikbas, U.M.,Wong, J.T.,Chen, Y.S.,Lallous, N.,Van Petegem, F.,Lack, N.A. (deposition date: 2025-04-11, release date: 2026-04-15)

• Primary citation: Dikbas, U.M.,Wong, J.T.,Chen, Y.S.,Lallous, N.,Van Petegem, F.,Lack, N.A.; Structural and Biochemical Characterization of HOXB13 Homeobox Domain Germline Mutations Driving Prostate Cancer; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)