9MK3

Engineered AsCas12a (M537R, F870L)

Summary for 9MK3

• Entry DOI: 10.2210/pdb9mk3/pdb
• Descriptor: CRISPR-associated endonuclease Cas12a, gRNA (41-MER), TS DNA (31-MER), ... (8 entities in total)
• Functional Keywords: dna endonuclease, splicing, splicing-dna-rna complex, splicing/dna/rna
• Biological source: Acidaminococcus; More
• Total number of polymer chains: 8
• Total formula weight: 358623.53

Authors

Dementiev, A.,White, A.,Olland, A.M.,Suto, R.K. (deposition date: 2024-12-16, release date: 2025-12-24)

• Primary citation: Jansson-Fritzberg, L.,Chica, B.,Latrick, C.,Olland, A.,Dementiev, A.,White, A.,Lemercier, J.,Wolk, S.K.; Mechanistic basis for improved activity of Engineered AsCas12a; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.698 Å)