9LWC

Cryo-EM structure of epinephrine bound dopamine receptor 1 D1R-M74-miniGs-Gbeta1gamma2-Nb35 complex

Summary for 9LWC

• Entry DOI: 10.2210/pdb9lwc/pdb
• EMDB information: 63440
• Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: gpcr, complex, dopamine receptor 1, agonist, membrane protein/immune system, membrane protein-immune system complex
• Biological source: Homo sapiens; More
• Total number of polymer chains: 5
• Total formula weight: 129360.27

Authors

Zhang, X.,Gao, K.,Liu, X. (deposition date: 2025-02-14, release date: 2026-02-18)

• Primary citation: Zhang, X.,Gao, K.,Liu, X.; Cryo-EM structure of dopamine bound mut-beta2-Adrenergic Receptor-miniGs-Nb35-scFv16 complex; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.9 Å)