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9LWC

Cryo-EM structure of epinephrine bound dopamine receptor 1 D1R-M74-miniGs-Gbeta1gamma2-Nb35 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortpolymer24428222.11Homo sapiens
2B
(B)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer30333213.31UniProt (P62873)
Pfam (PF25391)
Homo sapiens (human)Transducin beta chain 1
3C
(G)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer252749.21UniProt (P59768)
Pfam (PF00631)
Homo sapiens (human)G gamma-I
4D
(N)
Nanobody 35polymer13414714.31Vicugna pacos
5E
(R)
D(1A) dopamine receptor D1R-M74polymer45450278.21Homo sapiens (human)
6F
(R)
L-EPINEPHRINEnon-polymer183.21Chemie (ALE)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight129177.1
Non-Polymers*Number of molecules1
Total formula weight183.2
All*Total formula weight129360.3
*Water molecules are not included.

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PDB entries from 2026-02-25

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