9L1S

Structure of the HER2 (S310F) - pertuzumab (T30S/D31A) complex

Summary for 9L1S

• Entry DOI: 10.2210/pdb9l1s/pdb
• EMDB information: 62753
• Descriptor: Receptor tyrosine-protein kinase erbB-2, Pertuzumab Fab light chain, Pertuzumab Fab heavy chain (3 entities in total)
• Functional Keywords: antigen, antibody, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 118045.01

Authors

Xu, L.,Guo, J. (deposition date: 2024-12-15, release date: 2025-01-01)

• Primary citation: Bai, X.,Xu, L.,Wang, Z.,Zhuang, X.,Ning, J.,Sun, Y.,Wang, H.,Guo, Y.,Xu, Y.,Guo, J.,Chen, S.,Pan, L.; Computational-Aided Rational Mutation Design of Pertuzumab to Overcome Active HER2 Mutation S310F through Antibody-Drug Conjugates; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3 Å)