9L1S
Structure of the HER2 (S310F) - pertuzumab (T30S/D31A) complex
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| C | TYR194-HIS200 | |
| B | TYR192-HIS198 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"20696930","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2A91","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MZW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PDB","id":"1N8Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1S78","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2A91","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N85","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15093539","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19299620","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20696930","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1N8Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1S78","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2A91","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MZW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N85","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15093539","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19299620","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1S78","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"20696930","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3MZW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
