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9JKR

human GM-CSF with Fabs from autoantibodies, F1 and C.

Summary for 9JKR
Entry DOI10.2210/pdb9jkr/pdb
EMDB information61569
DescriptorFab region of F1 antibody heavy chain, Fab region of F1 antibody light chain, Fab region of C antibody heavy chain, ... (5 entities in total)
Functional Keywordsautoimmune pulmonary alveolar proteinosis, autoantibody, immune system
Biological sourceHomo sapiens
More
Total number of polymer chains5
Total formula weight115294.02
Authors
Kishikawa, J.,Kato, T.,Kurosaki, T.,Inoue, T. (deposition date: 2024-09-17, release date: 2026-03-25)
Primary citationFutami, S.,Kawai, C.,Kishikawa, J.,Hirose, M.,Kida, H.,Wang, P.H.,Yamashita, K.,Ishikawa, F.,Kato, T.,Inoue, Y.,Kumanogoh, A.,Kurosaki, T.,Inoue, T.
Mechanism of GM-CSF autoantibody-induced pathogenicity in autoimmune pulmonary alveolar proteinosis
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.7 Å)
Structure validation

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PDB entries from 2026-03-25

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