9JKR
human GM-CSF with Fabs from autoantibodies, F1 and C.
Summary for 9JKR
| Entry DOI | 10.2210/pdb9jkr/pdb |
| EMDB information | 61569 |
| Descriptor | Fab region of F1 antibody heavy chain, Fab region of F1 antibody light chain, Fab region of C antibody heavy chain, ... (5 entities in total) |
| Functional Keywords | autoimmune pulmonary alveolar proteinosis, autoantibody, immune system |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 5 |
| Total formula weight | 115294.02 |
| Authors | Kishikawa, J.,Kato, T.,Kurosaki, T.,Inoue, T. (deposition date: 2024-09-17, release date: 2026-03-25) |
| Primary citation | Futami, S.,Kawai, C.,Kishikawa, J.,Hirose, M.,Kida, H.,Wang, P.H.,Yamashita, K.,Ishikawa, F.,Kato, T.,Inoue, Y.,Kumanogoh, A.,Kurosaki, T.,Inoue, T. Mechanism of GM-CSF autoantibody-induced pathogenicity in autoimmune pulmonary alveolar proteinosis To Be Published, |
| Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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